TOPK

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18 produits

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  1. Ilaprazole, Potassium-transporting ATPase inhibitor
    CAS: 172152-36-2 Formule: C19H18N4O2S Poids moléculaire: 366.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — États-Unis Article #: I332490
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    Nom IUPAC
    2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
    SMILES
    CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC
    InChIKey
    HRRXCXABAPSOCP-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)
    Synonymes
    s3666 | ILAPRAZOLE [WHO-DD] | DTXSID10870115 | 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1h-b...
  2. Cephradine, Bacterial penicillin-binding protein inhibitor
    CAS: 38821-53-3 Numéro CE: 254-137-8 Formule: C16H19N3O4S Poids moléculaire: 349.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    ◐ .Sur commande · 8–12 semaines Article #: C423795
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    Nom IUPAC
    (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O
    InChIKey
    RDLPVSKMFDYCOR-UEKVPHQBSA-N
    InChI
    1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/show more
    Synonymes
    9YA6SX5S4D | AC-1409 | DTXSID4022785 | C74975 | Cefradina [INN-Spanish] | Cephradine [USAN:BAN] | Tox21_113488 | Velo...
  3. Cephradine monohydrate
    CAS: 75975-70-1 PubChem CID: 21124775 Formule: C16H19N3O4S.H2O Poids moléculaire: 367.42
    ● En stock — États-Unis Article #: C413264
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    Nom IUPAC
    (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
    SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O.O
    InChIKey
    VHNPSPMQGXQSET-CYJZLJNKSA-N
    InChI
    1S/C16H19N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-show more
    Synonymes
    CCG-268254 | CEFRADINE MONOHYDRATE [WHO-DD] | s5296 | SCHEMBL956675 | AKOS025310716 | Cephradinemonohydrate | cefradi...
  4. Cephradine, Bacterial penicillin-binding protein inhibitor
    CAS: 38821-53-3 Numéro CE: 254-137-8 Formule: C16H19N3O4S Poids moléculaire: 349.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — États-Unis Article #: C103344
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    Identificateurs techniques
    Nom IUPAC
    (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O
    InChIKey
    RDLPVSKMFDYCOR-UEKVPHQBSA-N
    InChI
    1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/show more
    Synonymes
    9YA6SX5S4D | AC-1409 | DTXSID4022785 | C74975 | Cefradina [INN-Spanish] | Cephradine [USAN:BAN] | Tox21_113488 | Velo...
  5. Cephradine
    CAS: 38821-53-3 Numéro CE: 254-137-8 Formule: C16H19N3O4S Poids moléculaire: 349.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● En stock — États-Unis Article #: C141296
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    Tarifs et tailles des emballages
    Identificateurs techniques
    Nom IUPAC
    (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
    SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O
    InChIKey
    RDLPVSKMFDYCOR-UEKVPHQBSA-N
    InChI
    1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/show more
    Synonymes
    9YA6SX5S4D | AC-1409 | DTXSID4022785 | C74975 | Cefradina [INN-Spanish] | Cephradine [USAN:BAN] | Tox21_113488 | Velo...
  6. Cephradine monohydrate
    CAS: 75975-70-1 PubChem CID: 21124775 Formule: C16H19N3O4S.H2O Poids moléculaire: 367.42
    10mM in Water
    ● En stock — États-Unis Article #: C425862
    Voir le produit
    Tarifs et tailles des emballages
    Identificateurs techniques
    Nom IUPAC
    (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
    SMILES
    CC1=C(N2C(C(C2=O)NC(=O)C(C3=CCC=CC3)N)SC1)C(=O)O.O
    InChIKey
    VHNPSPMQGXQSET-CYJZLJNKSA-N
    InChI
    1S/C16H19N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-show more
    Synonymes
    CCG-268254 | CEFRADINE MONOHYDRATE [WHO-DD] | s5296 | SCHEMBL956675 | AKOS025310716 | Cephradinemonohydrate | cefradi...
  7. HI TOPK 032
    CAS: 487020-03-1 Formule: C20H11N5OS Poids moléculaire: 369.4
    ● En stock — États-Unis Article #: H288486
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    Nom IUPAC
    N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)thiophene-2-carboxamide
    SMILES
    C1=CC=C2C(=C1)N=C3C(=C4C=C(C=CN4C3=N2)NC(=O)C5=CC=CS5)C#N
    InChIKey
    BCSBXWKRZUPFHW-UHFFFAOYSA-N
    InChI
    1S/C20H11N5OS/c21-11-13-16-10-12(22-20(26)17-6-3-9-27-17)7-8-25(16)19-18(13)23-14-4-1-2-5-15(14)24-19/h1-10H,(H,22,26)
    Synonymes
    SCHEMBL15270774 | NCGC00379159-05 | 2-Thiophenecarboxamide, N-(12-cyanoindolizino(2,3-b)quinoxalin-2-yl)- | N-(12-Cya...
  8. HI TOPK 032
    CAS: 487020-03-1 Numéro CE: 806-165-2 Formule: C20H11N5OS Poids moléculaire: 369.4
    10mM in DMSO
    ● En stock — États-Unis Article #: H424220
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    Identificateurs techniques
    Nom IUPAC
    N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)thiophene-2-carboxamide
    SMILES
    C1=CC=C2C(=C1)N=C3C(=C4C=C(C=CN4C3=N2)NC(=O)C5=CC=CS5)C#N
    InChIKey
    BCSBXWKRZUPFHW-UHFFFAOYSA-N
    InChI
    1S/C20H11N5OS/c21-11-13-16-10-12(22-20(26)17-6-3-9-27-17)7-8-25(16)19-18(13)23-14-4-1-2-5-15(14)24-19/h1-10H,(H,22,26)
    Synonymes
    SCHEMBL15270774 | NCGC00379159-05 | 2-Thiophenecarboxamide, N-(12-cyanoindolizino(2,3-b)quinoxalin-2-yl)- | N-(12-Cya...
  9. Ilaprazole sodium
    CAS: 172152-50-0 Formule: C19H17N4NaO2S Poids moléculaire: 388.42
    ● En stock — États-Unis Article #: I413292
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    Identificateurs techniques
    Nom IUPAC
    sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide
    SMILES
    CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]
    InChIKey
    ZQGDDMFDBZPGCD-UHFFFAOYSA-N
    InChI
    1S/C19H17N4O2S.Na/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23;/h3-11H,12H2,1-2H3;/q-1;+1
    Synonymes
    AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-...
  10. Ilaprazole, Potassium-transporting ATPase inhibitor
    CAS: 172152-36-2 Formule: C19H18N4O2S Poids moléculaire: 366.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● En stock — États-Unis Article #: I422116
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    Tarifs et tailles des emballages
    Identificateurs techniques
    Nom IUPAC
    2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
    SMILES
    CC1=C(C=CN=C1CS(=O)C2=NC3=C(N2)C=C(C=C3)N4C=CC=C4)OC
    InChIKey
    HRRXCXABAPSOCP-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)
    Synonymes
    s3666 | ILAPRAZOLE [WHO-DD] | DTXSID10870115 | 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1h-b...
  11. Ilaprazole sodium
    CAS: 172152-50-0 Formule: C19H17N4NaO2S Poids moléculaire: 388.42
    10mM in DMSO
    ● En stock — États-Unis Article #: I422117
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    Tarifs et tailles des emballages
    Identificateurs techniques
    Nom IUPAC
    sodium;2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-5-pyrrol-1-ylbenzimidazol-3-ide
    SMILES
    CC1=C(C=CN=C1CS(=O)C2=NC3=C([N-]2)C=C(C=C3)N4C=CC=C4)OC.[Na+]
    InChIKey
    ZQGDDMFDBZPGCD-UHFFFAOYSA-N
    InChI
    1S/C19H17N4O2S.Na/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23;/h3-11H,12H2,1-2H3;/q-1;+1
    Synonymes
    AKOS037515492 | HY-B2145 | 1H-Benzimidazole, 2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-...
  12. OTS964
    CAS: 1338545-07-5 Formule: C23H24N2O2S.HCl Poids moléculaire: 428.97
    10mM in DMSO
    ● En stock — États-Unis Article #: O421282
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    Identificateurs techniques
    Nom IUPAC
    9-[4-[(2R)-1-(dimethylamino)propan-2-yl]phenyl]-8-hydroxy-6-methyl-5H-thieno[2,3-c]quinolin-4-one;hydrochloride
    SMILES
    CC1=CC(=C(C2=C1NC(=O)C3=C2C=CS3)C4=CC=C(C=C4)C(C)CN(C)C)O.Cl
    InChIKey
    YHPWOYBWUWSJDW-UQKRIMTDSA-N
    InChI
    1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17-9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-;show more
    Synonymes
    SCHEMBL15092325 | OTS964 hydrochloride | AKOS030526420 | C72349 | 9-[4-[(2R)-1-(dimethylamino)propan-2-yl]phenyl]-8-h...
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Foire aux questions

Which compounds are listed for TOPK?
Compounds associated with TOPK are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does TOPK sit within Cell Cycle/DNA Damage?
TOPK is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from TOPK?
For compounds listed under TOPK, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for TOPK?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring TOPK, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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