Uridine - pour la culture cellulaire, ≥99% , CAS No.58-96-8

CAS: 58-96-8 Cat. No.: U108811 Formule: C₉H₁₂N₂O₆ Poids moléculaire: 244.20 Beilstein Registry Number: 754902 Numéro CE: 200-407-5

QUALITÉ & PURETÉ for Cell culture, ≥99%

Synonyms

1-beta-D-Ribofuranosyluracil|Urd|ADENOSINE IMPURITY F (EP IMPURITY)|1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione|URIDINE (MART.)|URIDINE [USP IMPURITY]|1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione|Uracil riboside|1-b-D-Ribofuranosyluracil|.beta.-D-Ribofuranoside, 2,4(1H,3H)-pyrimidinedione-1|URIDINE (USP IMPURITY)|Uridine,(S)|1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione|1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione|Uracil-1-.beta.-d-ribofuranoside|beta-D-ribofuranosyl-uridine|1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione|Uracil, 1-beta-D-ribofuranosyl-|uridine|URIDINE [INCI]|URIDINE [MI]|URIDINE [USP-RS]|1-((2R,3R,4S,5R)-tetrahydro-3,4-dihydroxy-5-(hydroxymethyl)furan-2-yl)pyrimidine-2,4(1H,3H)-dione|ADENOSINE IMPURITY F [EP IMPURITY]|1-beta-D-Ribofuranosyluracil, Uracil-1-beta-D-ribofuranoside|.beta.-Uridine|1-.BETA.-D-RIBOFURANOSYLPYRIMIDINE-2,4(1H,3H)-DIONE|Opera_ID_118|Uridin|URIDINE (USP-RS)|URIDINE [WHO-DD]|1-beta-delta-Ribofuranosyluracil|b-D-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1|1-.beta.-D-Ribofuranosyluracil|1-beta-delta-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione|1-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione (Uridine)|d-Ribosyl uracil|URIDINE [MART.]|1-A-D-Ribofuranosyluracil|beta-Uridine|1-.beta.-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione|1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione|Uracil-1-A-D-ribofuranoside|b-Uridine

Storage

A conserver entre 2 et 8°C

Shipped In

Glace humide

Vue d’ensemble

Présentation du produit

L'uridine est un nucléoside de l'uracile, spécifique de la séquence de l'ARN. L'uridine est présente dans le sang, le liquide séminal et le liquide céphalo-rachidien. L'uridine est un substrat pour la synthèse des nucléotides dans les organismes vivants par les voies de novo et de récupération.

Application

L'uridine a été utilisée

comme inhibiteur de la prolifération des cellules de Schwann dans la culture des neurones des ganglions de la racine dorsale du rat (DRG)

comme supplément de milieu pour la culture d'épiblastes

comme composant de la solution mère de 5-fluoro-2′-désoxyuridine utilisée pour la culture de neurones

Spécifications

Synonymes

1-beta-D-Ribofuranosyluracil | Urd | ADENOSINE IMPURITY F (EP IMPURITY) | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione | URIDINE (MART.) | URIDINE [USP IMPURITY] | 1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione | Uracil riboside | 1-b-D-Ribofuranosyluracil | .beta.-D-Ribofuranoside, 2 Afficher plus

Spécifications et pureté

pour la culture cellulaire, ≥99%

Conditions de stockage de stockage

A conserver entre 2 et 8°C

Expédié en

Glace humide

Grade

for Cell culture

Pureté

≥99%

Noms et identifiants

Pubchem Sid

488179988

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488179988

Sourires canoniques

C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChIKey

DRTQHJPVMGBUCF-XVFCMESISA-N

INCHI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

Isomères SMILES

C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

WGK Allemagne

3

Poids moléculaire

244.20

Beilstein

754902

Reaxy-Rn

4699706

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4699706&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Classe Pyrimidine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Classe: Pyrimidine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrimidine nucleosides
• Alternative Parents: Glycosylamines Pentoses Pyrimidones Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Vinylogous amides Ureas Lactams Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Pyrimidone - Hydropyrimidine - Monosaccharide - Pyrimidine - Vinylogous amide - Tetrahydrofuran - Heteroaromatic compound - Urea - Secondary alcohol - Lactam - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Primary alcohol - Alcohol - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: Ribonucleosides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Uck1 Uridine-cytidine kinase 1 (5 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in water (50 mg/ml), DMSO, and methanol.
• Rotation spécifique [α]: 9 ° (C=2, H2O)
• Point de fusion (°C): 163-167°C
• Poids moléculaire: 244.200 g/mol
• XLogP3: -2.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 244.07 Da
• Monoisotopic Mass: 244.07 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 370.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1