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Cholesterol - BioReagent, for cell culture, ≥99%, Powder , CAS No.57-88-5

CAS: 57-88-5 Cat. No.: C476640 分子式: C27H46O 分子量: 386.65 Beilstein Registry Number: 1915888 EC番号: 200-353-2
581 Citations COA
Cholesterol - BioReagent, for cell culture, ≥99%, Powder , CAS No.57-88-5
注文可能
グレード＆純度 BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. ≥99% Powder
Synonyms
3-beta-Hydroxycholest-5-ene | 3beta-Hydroxycholest-5-ene | Dusoran | epicholesterin | Nimco cholesterol base H | Cholesterol,(S) | 20-epi-cholesterol | AI3-03112 | 3beta-cholest-5-en-3-ol | 5-Cholesten-3ss--ol | 5:6-Cholesten-3-ol | Lidinit | 3.beta.-Hydr
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
サイズ
USA
ドイツ (EU)*
価格
個数
5g
C476640-5g
2 在庫あり
—
$164.90
25g
C476640-25g
3 在庫あり
—
$659.90
100g
C476640-100g
1 在庫あり
—
$2,109.90
Enter a quantity for the sizes you want to add.
バルク / カスタム
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SDS
Safety data
COA
Certificate
DS
データシート
SP
仕様書
概要 仕様 名前と識別子 ドキュメント 詳細データ Taxonomic Classification 3 D構造 関連ターゲット（人間） 関連ターゲット（非人間） 作用メカニズム 証明書（CoA、COO、BSE/TSEと分析図） 化学的性質と物理的性質 よくある質問と記事 Citations of This Product ソリューション計算機 レビュー
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このグレードを選ぶ理由

BioReagent, for cell culture, ≥99%, Powder BioReagent,細胞培養用 ベースライン干渉を最小限に抑える必要がある、感度の高いクロマトグラフィーおよび分析ワークフロー向け。

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保管・配送

Store at -20°C Ice chest + Ice pads に出荷。正確な仕様については、ロット固有の COA をご確認ください。

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品質書類

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文献的裏付け

クロマトグラフィー、有機合成、クロスカップリング反応に関する 581 件の査読済み論文で引用されています。

概要

Cholesterol, a major sterol is the precursor for steroid hormones, bile acid and vitamin in mammals and coordinates endocytosis. It complexes with protein to form lipoproteins for transport in blood. It exists either as high-density lipoprotein (HDL) or low-density lipoprotein (LDL). HDL also called good cholesterol has less lipid content. LDL or bad cholesterol has high lipid content. Statin inhibition of HMG-CoA reductase enzyme in the cholesterol biosynthesis pathway controls elevated cholesterol levels in atherosclerosis and hypercholesterolemia. Low levels of cholesterol results in hypothyroidism, familial hypobetalipoproteinemia and liver disease. Imbalance of cholesterol homeostasis and intracellular cholesterol levels play a key role in cancer development. High cholesterol levels favor breast cancer progression.Cholesterol has been used:as a medium supplement in chorionic villous tissue culture form placentaas a component of hormone pellet for implantation in mice ovaryfor inducing expression of immunity-related GTPase M (IRGM) in human monocytic cell line, THP-1

仕様

同義語
3-beta-Hydroxycholest-5-ene | 3beta-Hydroxycholest-5-ene | Dusoran | epicholesterin | Nimco cholesterol base H | Cholesterol,(S) | 20-epi-cholesterol | AI3-03112 | 3beta-cholest-5-en-3-ol | 5-Cholesten-3ss--ol | 5:6-Cholesten-3-ol | Lidinit | 3.beta.-Hydr
仕様と純度
BioReagent, for cell culture, ≥99%, Powder
生化学的・生理学的メカニズム
Major component of all biological membranes; ~25% of total brain lipid is cholesterol.
保管条件
Store at -20°C
入荷
Ice chest + Ice pads
この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。
等級
BioReagent, 細胞培養用
純度
≥99%
名前と識別子
パブケム・シド
504750982
パブケム・シド・ウル
https://pubchem.ncbi.nlm.nih.gov/substance/504750982
カノニカル・スマイル
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
IUPAC Name
(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey
HVYWMOMLDIMFJA-DPAQBDIFSA-N
INCHI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
異性体SMILES
C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
WGKドイツ
1
RTECS
FZ8400000
分子量
386.65
Beilstein
1915888
Reaxy-Rn
2060565
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2060565&ln=

ドキュメント

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✅ 分析証明書（COA）

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📊 データシート

製品仕様と用途のクイックリファレンス概要。

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🔬 仕様書

このグレードの完全な品質特性と合格基準。

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詳細データ

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
分類Steroids and steroid derivatives
SubclassCholestane steroids
Intermediate Tree Nodes Not available
Direct ParentCholesterols and derivatives
Alternative Parents 3-beta-hydroxysteroids  3-beta-hydroxy delta-5-steroids  Delta-5-steroids  Secondary alcohols  Cyclic alcohols and derivatives  Hydrocarbon derivatives  
Molecular FrameworkAliphatic homopolycyclic compounds
Substituents Cholesterol-skeleton - Cholesterol - 3-beta-hydroxysteroid - 3-beta-hydroxy-delta-5-steroid - Hydroxysteroid - 3-hydroxysteroid - 3-hydroxy-delta-5-steroid - Delta-5-steroid - Cyclic alcohol - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homopolycyclic compound
説明This compound belongs to the class of organic compounds known as cholesterols and derivatives. These are compounds containing a 3-hydroxylated cholestane core.
External Descriptors Cholesterol and derivatives
3 D構造
インタラクティブ化学構造モデル





関連ターゲット（人間）
CYP46A1 Tchem Cholesterol 24-hydroxylase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RORC Tchem Nuclear receptor ROR-gamma (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP11A1 Tclin Cytochrome P450 11A1 (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLA1 Tclin DNA polymerase alpha subunit (225 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NPC1L1 Tclin Niemann-Pick C1-like protein 1 (346 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR1H3 Tchem LXR-alpha (2891 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCRF-CEM (65223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SH-SY5Y (11521 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U-937 (7138 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BJ (6930 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
T47D (39041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H69 (709 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMMC-7721 (5516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCG2 Tchem ATP-binding cassette sub-family G member 2 (4927 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SULT2B1 Tbio Sulfotransferase family cytosolic 2B member 1 (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP46A1 Tchem Cholesterol 24-hydroxylase (289 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
関連ターゲット（非人間）
ERG11 Cytochrome P450 51 (617 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Top2 DNA topoisomerase II (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pyogenes (16140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus sp. (164 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cutibacterium acnes (887 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P19 (309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vero (26788 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
C2C12 (756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
cyp125 Putative cytochrome P450 125 (56 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
env Envelope glycoprotein (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phytophthora cactorum (113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brucella pseudogrignonensis (43 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Scn2a Sodium channel alpha subunits; brain (Types I, II, III) (344 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
作用メカニズム
証明書（CoA、COO、BSE/TSEと分析図）
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate Type日付商品
F2629013F2629013Certificate of AnalysisJul 06, 2026 C476640
G2327143G2327143Certificate of AnalysisMay 19, 2026 C476640
G2327147G2327147Certificate of AnalysisMay 19, 2026 C476640
G2327150G2327150Certificate of AnalysisMay 19, 2026 C476640
G2327153G2327153Certificate of AnalysisMay 19, 2026 C476640
G2327157G2327157Certificate of AnalysisMay 19, 2026 C476640
C2514147C2514147Certificate of AnalysisJul 15, 2023 C476640
G2327163G2327163Certificate of AnalysisJul 15, 2023 C476640
G2425015G2425015Certificate of AnalysisJul 15, 2023 C476640
L2509035L2509035Certificate of AnalysisJul 15, 2023 C476640
化学的性質と物理的性質
溶解度 H2O: 0.002mg/mLTween: soluble; ethanol: soluble; serum: soluble
比旋光度［α］-37 ° (C=2, Dioxane)
沸点（°C）360°C
融点（°C）148.5°C
分子量386.700 g/mol
XLogP38.700
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count5
Exact Mass386.355 Da
Monoisotopic Mass386.355 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count28
Formal Charge0
Complexity591.000
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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How Palmitoyl Pentapeptide-4 Acts on the Skin: From the KTTKS Sequence and Skin Delivery to Collagen Matrix Responses
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Synthetic lipopeptides
How Cyclization Changes Peptide Behavior: Conformational Preorganization, Skin Delivery, and Integrin Binding, Using Cyclopeptide-5 as an Example
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Polypeptide Skincare
The Logic of Biomimetic Peptide Action in Skin: Sequence and Conformation, Skin Delivery, Stability, and Target Matching
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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liposomes Cell-Penetrating Peptides biomimetic peptides sequence mimicry signaling peptides stratum corneum delivery lipidation proteolytic stability cellular target matching extracellular matrix regulation
How Does Collagen Tripeptide Act on the Skin: Stratum Corneum Delivery, Matrix Protection, and Regulation of Collagen Homeostasis
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Extracellular matrix Fibroblasts stratum corneum delivery collagen tripeptide (CTP) Gly–X–Y sequence stratum corneum hydration matrix protection collagen homeostasis
Potential Mechanisms of p-Cymene in Problem-Prone Skin: Membrane Perturbation, Inflammatory Signaling Modulation, and Localized Delivery
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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p-cymene 1-isopropyl-4-methylbenzene
How Coenzyme Q10 Acts on the Skin: Mitochondrial Electron Transfer, Antioxidant Protection of Membrane Lipids, and Lipid-Carrier Delivery
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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liposomes photoaging lipid peroxidation coenzyme Q10 ubiquinone ubiquinol mitochondrial electron transfer oxidative phosphorylation nanostructured lipid carriers nanoemulsions
The Combination Logic of Palmitoyl Tripeptide-1 and Palmitoyl Pentapeptide-4: Skin Delivery, Matrix Signaling, and Regulation of Collagen Homeostasis
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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peptide palmitoyl chain
How Arbutin Regulates Melanin Production: α/β Anomeric Configuration and Tyrosinase Action
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Melanin Arbutin
Mechanistic Basis of Acetyl Hexapeptide-8 in the Management of Expression Lines: SNARE Complex Interference, Constraints on Percutaneous Delivery, and Combination Strategies
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Retinol Acetyl Hexapeptide-8 Argireline SNAP-25 SNARE complex expression lines transdermal delivery anti-wrinkle combinations
Niacinamide Brightening Mechanisms and Formulation Design: Melanosome Transfer, pH Regulation, and Combination Strategies
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Niacinamide
How Ectoine Regulates Skin Hydration: Zwitterionic Structure, Preferential Hydration, and Barrier-Support Mechanisms
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Skincare Ectoin Amino acid derivatives
Inflammasomes: Core Signaling Platforms and Targeted Research in Immunoinflammation
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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innate immunity AIM2 inflammasome NLRP3 pyroptosis IL-1β Caspase-1 GSDMD
Are Lipids Fats? Understanding the Multiple Functions of Lipids from Cellular Metabolism to mRNA Delivery
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Lipid metabolism Lipids Fatty acids Sphingolipids lipid peroxidation cellular senescence mRNA delivery Lipid Nanoparticles
Bakuchiol Is Not “Plant Retinol”: Chemical Structure, Anti-Aging Mechanisms, and Functional Similarities and Differences Compared with Retinol
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Retinol Bakuchiol
Structure, Emollient and Moisturizing Effects, and Source Identification of Squalane: From Complete Hydrogenation of Squalene to Stable Isotope Analysis
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Squalane
Why Do Skincare Oligopeptides Have Different Effects? — Molecular Structure, Skin Delivery, and Mechanisms of Action
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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IUPAC Oligopeptides
Stratum Corneum Penetration and Skin Mechanisms of Panthenol: Moisturization, Barrier Repair, and Soothing Effects
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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Panthenol pantothenic acid Vitamin B5 D-panthenol
From Tumor Sequencing to “One Patient, One Drug”: Machine-Learning-Assisted Design of V940 Individualized Neoantigen mRNA and the Phase III Breakthrough in Melanoma
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
Tags:
Tumors Tumor sequencing
Basis of Bisabolol’s Effects on Skin: Structure and Lipid Affinity, Inflammation Modulation, Antimicrobial Activity, and Percutaneous Penetration Enhancement
Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides
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cosmetics Bisabolol
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