Dihydroethidium - ≥95% , CAS No.104821-25-2

CAS: 104821-25-2 Cat. No.: D113494 分子式: C₂₁H₂₁N₃ 分子量: 315.41 Beilstein Registry Number: 5107482

グレード＆純度 ≥95%

Synonyms

Hydroethidine | J-100119 | AKOS015915966 | FT-0624954 | PH011085 | Hydroethidine;PD-MY 003 | Enoxacinum (Latin) | NSC-408120 | 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine | Q3027884 | BCP15712 | SCHEMBL79004

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

概要

Hydroethidine operates effectively as a probe for measurement of reactive oxygen species. The dye enters cells freely and is dehydrogenated to ethidium bromide. The probe has been used extensively with NK cell and as a vital dye for identification of proliferation and hypoxic cells in tumors. Studies have been performed using neutrophils and endothelial cells as well as HL60 cells and macrophages. A major advantage of this probe is its ability to distinguish between superoxide and H2O2. Fluorescence emission occurs at around 600 nm.
Redox indicator. Blue fluorescence until oxidized to ethidium

仕様

同義語

Hydroethidine | J-100119 | AKOS015915966 | FT-0624954 | PH011085 | Hydroethidine;PD-MY 003 | Enoxacinum (Latin) | NSC-408120 | 5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine | Q3027884 | BCP15712 | SCHEMBL79004

仕様と純度

≥95%

保管条件

Protected from light,Store at -20°C,Argon charged

入荷

Ice chest + Ice pads

この製品は冷冷この冷このこの製品の運送が必要です。地上およびその他の経済サービスは利用できません。

注

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

純度

≥95%

名前と識別子

パブケム・シド

504756991

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/504756991

カノニカル・スマイル

CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4

IUPAC Name

5-ethyl-6-phenyl-6H-phenanthridine-3,8-diamine

InChIKey

XYJODUBPWNZLML-UHFFFAOYSA-N

INCHI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3

異性体SMILES

CCN1C(C2=C(C=CC(=C2)N)C3=C1C=C(C=C3)N)C4=CC=CC=C4

WGKドイツ

3

分子量

315.41

Beilstein

5107482

Reaxy-Rn

5107482

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5107482&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Quinolines and derivatives
      • Subclass Phenylquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Quinolines and derivatives
• Subclass: Phenylquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylquinolines
• Alternative Parents: Phenanthridines and derivatives Aminoquinolines and derivatives Dialkylarylamines Aralkylamines Benzene and substituted derivatives Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phenylquinoline - Benzoquinoline - Phenanthridine - Aminoquinoline - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aralkylamine - Benzenoid - Monocyclic benzene moiety - Tertiary amine - Azacycle - Amine - Primary amine - Hydrocarbon derivative - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• 説明: This compound belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 感度: Air sensitive.Light sensitive.
• 分子量: 315.400 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 315.174 Da
• Monoisotopic Mass: 315.174 Da
• Topological Polar Surface Area: 55.300 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 419.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1