Keliximab (anti-CD4) - 一次抗体, specific to CD4

CAS: 174722-30-6 Cat. No.: Ab191955
注文可能
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
人間
Reactive species
人間
Isotype
Human IgG1
Conjugation
Unconjugated
Size
USA
ドイツ (EU)*
Price
Qty
100μg
Ab191955-100μg
3 在庫あり
$115.90
1mg
Ab191955-1mg
2 在庫あり
$571.90
5mg
Ab191955-5mg
1 在庫あり
$1,425.90
10mg
Ab191955-10mg
US製・受注生産 · 2~4週間 ·
$2,279.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

概要

Keliximab (anti-CD4) with a Ki value of 1.0 nM for soluble CD4. Keliximab (anti-CD4) blocks T cell proliferation and inhibits IL-2 production. Keliximab (anti-CD4) can be used for cancer research.

Specifications

Product Name
Keliximab (anti-CD4) - 一次抗体, specific to CD4
同義語
CD 4 antibody | CD4 (L3T4) antibody | CD4 antibody | CD4 antigen (p55) antibody | CD4 antigen antibody | CD4 molecule antibody | CD4 receptor antibody | CD4+ Lymphocyte deficiency, included antibody | CD4_HUMAN antibody | CD4mut antibody | L3T4 antibody |
仕様と純度
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
生化学的・生理学的メカニズム
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. Post-translational: Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts
宿主種
人間
特異性
CD4
活用
Unconjugated
等級
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
ライトチェーン・タイプ
lambda
SDS-PAGE
144.12 kDa
精製方法
Protein A purified
集中
See COA
CAS
174722-30-6
保管と配送
保管条件
Store at -80°C,Avoid repeated freezing and thawing
入荷
Dry ice packs + Cold packs
安定性と保管
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
画像

Keliximab (anti-CD4) (Ab191955) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling CD4 (red) with Keliximab (anti-CD4) (Ab191955) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Keliximab (anti-CD4) (Ab191955) - ELISA
Immobilized Recombinant Human CD4/TNFRSF5 protein (rp183577) at 1.0 μg/mL can bind Keliximab (anti-CD4) (Ab191955) with the EC₅₀ of 25.94 ng/mL.

Keliximab (anti-CD4) (Ab191955) - SEC
The purity of Keliximab (anti-CD4) (Ab191955) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

関連ターゲット(人間)
CD4 Tclin T-cell surface glycoprotein CD4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
作用メカニズム
証明書(CoA、COO、BSE/TSEと分析図)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
ソリューション計算機
レビュー

顧客レビュー

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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