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  1. Griseofulvin, Tubulin inhibitor
    CAS: 126-07-8 EC番号: 204-767-4 分子式: C17H17ClO6 分子量: 352.77
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● 在庫あり — 米国 商品 #: G101269
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    技術識別子
    IUPAC名
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    同義語
    CCRIS 320 | Grifulin | (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-...
  2. MK-1775, Serine/threonine-protein kinase WEE1 inhibitor
    CAS: 955365-80-7 EC番号: 680-342-0 分子式: C27H32N8O2 分子量: 500.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: M127160
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    技術識別子
    IUPAC名
    1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
    SMILES
    CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
    InChIKey
    BKWJAKQVGHWELA-UHFFFAOYSA-N
    InChI
    1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-show more
    同義語
    MK-1775(AZD-1775,Adavosertib) | 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenyla...
  3. Griseofulvin
    CAS: 126-07-8 EC番号: 204-767-4 分子式: C17H17ClO6 分子量: 352.77
    固体 ≥97%
    ● 在庫あり — 米国 商品 #: G101270
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    技術識別子
    IUPAC名
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    同義語
    Grisovin | Curling factor | Fulcin | Likuden | Grizeofulvin | Griseofulvina | Grifulvin | Grysio | Delmofulvina | Gri...
  4. PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
    CAS: 185039-89-8 PubChem CID: 5311382 分子式: C26H27Cl2N5O2 分子量: 512.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● 在庫あり — 米国 商品 #: P276244
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    技術識別子
    IUPAC名
    6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one
    SMILES
    CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
    InChIKey
    IFPPYSWJNWHOLQ-UHFFFAOYSA-N
    InChI
    1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more
    同義語
    AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
  5. Bosutinib Isomer 1, Free Base
    CAS: 1391063-17-4 PubChem CID: 5328940 分子式: C26H29Cl2N5O3 分子量: 530.45
    ◐ .受注生産 · 8~12週間 商品 #: B330520
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    同義語
    Bosutinib,SKI-606 | BSPBio_001023 | NCGC00241107-03 | NSC799367 | NSC-799367 | 4-(2,4-Dichloro-5-methoxy-phenylamino)...
  6. Griseofulvin, Tubulin inhibitor
    CAS: 126-07-8 EC番号: 204-767-4 分子式: C17H17ClO6 分子量: 352.77
    液体 10mM in DMSO
    ● 在庫あり — 米国 商品 #: G421095
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    技術識別子
    IUPAC名
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    同義語
    griseofulvin|126-07-8|Amudane|(+)-Griseofulvin|Griseofulvinum|Grisactin|Grifulvin|Grisefuline|Griseofulvina|Grisofulv...
  7. PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
    CAS: 185039-89-8 PubChem CID: 5311382 分子式: C26H27Cl2N5O2 分子量: 512.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● 在庫あり — 米国 商品 #: P422267
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    技術識別子
    IUPAC名
    6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one
    SMILES
    CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
    InChIKey
    IFPPYSWJNWHOLQ-UHFFFAOYSA-N
    InChI
    1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more
    同義語
    AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
  8. Wee1 inhibitor
    CAS: 622855-37-2 PubChem CID: 10384072 分子式: C20H11ClN2O3 分子量: 362.77
    ◐ .受注生産 · 8~12週間 商品 #: W342954
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    技術識別子
    IUPAC名
    4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
    SMILES
    C1=CC=C(C(=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O)Cl
    InChIKey
    DPEXRCOBPACFOO-UHFFFAOYSA-N
    InChI
    1S/C20H11ClN2O3/c21-13-4-2-1-3-10(13)11-8-15-16(18-17(11)19(25)23-20(18)26)12-7-9(24)5-6-14(12)22-15/h1-8,22,24H,(H,23,25,26)
    同義語
    BDBM50192371 | Wee1 Inhibitor I | Wee1-Inhibitor-I | MS-25768 | HY-108343 | Wee1 Inhibitor-I | SCHEMBL5828030 | Wee1 ...
  9. Azenosertib (Zn-C3), Inhibitor of WEE1 G2 checkpoint kinase
    CAS: 2376146-48-2 EC番号: 189-014-7 PubChem CID: 139467635 分子式: C29H34N8O2 分子量: 526.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: A607901
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    技術識別子
    IUPAC名
    1-[(7R)-7-ethyl-7-hydroxy-5,6-dihydrocyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
    SMILES
    O=c1n(CC=C)n(c2ccc3CC[C@@](CC)(O)c3n2)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc12
    InChIKey
    OXTSYWDBUVRXFF-GDLZYMKVSA-N
    InChI
    1S/C29H34N8O2/c1-4-14-36-27(38)23-19-30-28(31-21-7-9-22(10-8-21)35-17-15-34(3)16-18-35)33-26(23)37(36)24-11-6-20-12-13-29(39,5-2)25(20)32-24/h4,6-11,1show more
    同義語
    compound 16 [PMID: 34423975] | azenosertib | Azenosertib [INN] | EX-A6113 | 9J13XU96Z1 | (R)-2-allyl-1-(7-ethyl-7-hyd...
  10. WEE1-IN-3
    CAS: 2272976-28-8 PubChem CID: 137471996 分子式: C28H31N7O2 分子量: 497.59
    ◐ .受注生産 · 8~12週間 商品 #: W648627
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    技術識別子
    IUPAC名
    1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[(2-methylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidishow more
    SMILES
    CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC5=C(C=C4)C6(CC6)CN(C5)C)O
    InChIKey
    JSZFIXAMFNNRKS-UHFFFAOYSA-N
    InChI
    1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37Hshow more
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よくある質問

How is the Wee1 listing put together?
It draws on reported Wee1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Wee1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Wee1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Wee1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Wee1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Wee1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Wee1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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