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  1. CGP 57380, Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 522629-08-9 EC番号: 637-056-6 分子式: C11H9FN6 分子量: 244.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: C274776
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    IUPAC名
    3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
    SMILES
    C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
    InChIKey
    UQPMANVRZYYQMD-UHFFFAOYSA-N
    InChI
    1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)
    同義語
    NSC 741567 | SR-02000000869 | A902707 | BISBENTIAMINE [MI] | NCIOpen2_009023 | SCHEMBL16714452 | NCGC00162380-01 | HM...
  2. CGP 57380, Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 522629-08-9 EC番号: 637-056-6 分子式: C11H9FN6 分子量: 244.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● 在庫あり — 米国 商品 #: C424479
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    IUPAC名
    3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
    SMILES
    C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
    InChIKey
    UQPMANVRZYYQMD-UHFFFAOYSA-N
    InChI
    1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)
    同義語
    CGP 57380|522629-08-9|CGP-57380|MNK1 Inhibitor|N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine|3-N-(4-fl...
  3. Cercosporamide
    CAS: 131436-22-1 EC番号: 803-029-4 分子式: C16H13NO7 分子量: 331.28
    ◐ .受注生産 · 8~12週間 商品 #: C287456
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    IUPAC名
    (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
    SMILES
    CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
    InChIKey
    GEWLYFZWVLXQME-MRXNPFEDSA-N
    InChI
    1S/C16H13NO7/c1-5(18)10-7(20)4-9-16(2,14(10)22)12-8(21)3-6(19)11(15(17)23)13(12)24-9/h3-4,19-21H,1-2H3,(H2,17,23)/t16-/m1/s1
    同義語
    (R)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9abeta-methyl-9-oxodibenzofuran-4-carboxamide | SCHEMBL12658718 | 4-Dibenz...
  4. ETC-206 (AUM 001), Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 1464151-33-4 分子式: C25H20N4O2 分子量: 408.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: E413572
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    技術識別子
    IUPAC名
    4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile
    SMILES
    C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
    InChIKey
    FWRFPHJSGLYXTD-UHFFFAOYSA-N
    InChI
    1S/C25H20N4O2/c26-15-18-1-3-20(4-2-18)23-16-27-24-10-9-22(17-29(23)24)19-5-7-21(8-6-19)25(30)28-11-13-31-14-12-28/h1-10,16-17H,11-14H2
    同義語
    HY-112424 | F88611 | AUM001 | AUM-001 | s6658 | MND3WX2R7I | MS-27017 | 4-{6-[4-(morpholine-4-carbonyl)phenyl]imidazo...
  5. ETC-206 (AUM 001), Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 1464151-33-4 分子式: C25H20N4O2 分子量: 408.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● 在庫あり — 米国 商品 #: E421695
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    IUPAC名
    4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile
    SMILES
    C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
    InChIKey
    FWRFPHJSGLYXTD-UHFFFAOYSA-N
    InChI
    1S/C25H20N4O2/c26-15-18-1-3-20(4-2-18)23-16-27-24-10-9-22(17-29(23)24)19-5-7-21(8-6-19)25(30)28-11-13-31-14-12-28/h1-10,16-17H,11-14H2
    同義語
    HY-112424 | F88611 | AUM001 | AUM-001 | s6658 | MND3WX2R7I | MS-27017 | 4-{6-[4-(morpholine-4-carbonyl)phenyl]imidazo...
  6. SEL201
    CAS: 2095704-43-9 PubChem CID: 129052025 分子式: C19H15ClN4O 分子量: 350.8
    ● 在庫あり — 米国 商品 #: S413668
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    技術識別子
    IUPAC名
    5-(3-amino-1H-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one
    SMILES
    C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N
    InChIKey
    YQVUADHJKWJHAF-UHFFFAOYSA-N
    InChI
    1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)
    同義語
    SLV-2436 | SEL201-882(1H)​-​Pyridinone,5-​(3-​amino-​1H-​indazol-​6-​yl)​-​1-​[(3-​chlorophenyl)​methyl]​-
  7. SEL201
    CAS: 2095704-43-9 PubChem CID: 129052025 分子式: C19H15ClN4O 分子量: 350.8
    10mM in DMSO
    ◐ .受注生産 · 8~12週間 商品 #: S422541
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    技術識別子
    IUPAC名
    5-(3-amino-1H-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one
    SMILES
    C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N
    InChIKey
    YQVUADHJKWJHAF-UHFFFAOYSA-N
    InChI
    1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)
    同義語
    SLV-2436 | SEL201-882(1H)​-​Pyridinone,5-​(3-​amino-​1H-​indazol-​6-​yl)​-​1-​[(3-​chlorophenyl)​methyl]​-
  8. Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17a
    CAS: 1849590-01-7 PubChem CID: 118598754 分子式: C17H20N6O2 分子量: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● 在庫あり — 米国 商品 #: T413958
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    IUPAC名
    6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione
    SMILES
    CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3
    InChIKey
    HKTBYUWLRDZAJK-UHFFFAOYSA-N
    InChI
    1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)
    同義語
    (R)-Pulegone - 90% | 1849590-01-7 | UNII-U2H19X4WBV | 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexa...
  9. Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17a
    CAS: 1849590-01-7 PubChem CID: 118598754 分子式: C17H20N6O2 分子量: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ◐ .受注生産 · 8~12週間 商品 #: T422265
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    技術識別子
    IUPAC名
    6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione
    SMILES
    CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3
    InChIKey
    HKTBYUWLRDZAJK-UHFFFAOYSA-N
    InChI
    1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)
    同義語
    (R)-Pulegone - 90% | 1849590-01-7 | UNII-U2H19X4WBV | 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexa...
  10. HG-10-102-01, Inhibitor of Janus kinase 2;Inhibitor of leucine rich repeat kinase 2
    CAS: 1351758-81-0 分子式: C17H20ClN5O3 分子量: 377.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: C358747
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    技術識別子
    IUPAC名
    [4-[[5-chloro-4-(methylamino)pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone
    SMILES
    CNC1=NC(=NC=C1Cl)NC2=C(C=C(C=C2)C(=O)N3CCOCC3)OC
    InChIKey
    YEVOZZZLKJKCCD-UHFFFAOYSA-N
    InChI
    1S/C17H20ClN5O3/c1-19-15-12(18)10-20-17(22-15)21-13-4-3-11(9-14(13)25-2)16(24)23-5-7-26-8-6-23/h3-4,9-10H,5-8H2,1-2H3,(H2,19,20,21,22)
    同義語
    [4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone | (E)-(4-((5-chloro-6-(met...
  11. HG-10-102-01
    CAS: 1351758-81-0 分子式: C17H20ClN5O3 分子量: 377.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .受注生産 · 8~12週間 商品 #: H1496348
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よくある質問

Which compounds are listed for MNK?
Compounds associated with MNK are grouped here under the MAPK/ERK Pathway classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does MNK sit within MAPK/ERK Pathway?
MNK is one target listing within the MAPK/ERK Pathway classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from MNK?
For compounds listed under MNK, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for MNK?
Browse the parent MAPK/ERK Pathway listing to reach targets neighbouring MNK, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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