MAPKAPK2(MK2)

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  1. RMM 46
    CAS: 1307896-46-3 PubChem CID: 67206797 分子式: C24H26N4O5 分子量: 450.5
    ◐ .受注生産 · 8~12週間 商品 #: R288282
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    技術識別子
    IUPAC名
    (E)-2-cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enamide
    SMILES
    CC(C)(CO)NC(=O)C(=CC1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)C#N
    InChIKey
    FCCMYBKAZCDQGX-LZYBPNLTSA-N
    InChI
    1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,show more
    同義語
    2-Cyano-N-(2-hydroxy-1,1-dimethylethyl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]-2-propenamide
  2. TC-S 7006, Inhibitor of mitogen-activated protein kinase kinase kinase 8
    CAS: 871307-18-5 EC番号: 111-094-9 PubChem CID: 9549300 分子式: C21H14ClFN6 分子量: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .受注生産 · 8~12週間 商品 #: T287927
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    技術識別子
    IUPAC名
    4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile
    SMILES
    C1=CC(=CN=C1)CNC2=NC=C3C(=C2)C(=C(C=N3)C#N)NC4=CC(=C(C=C4)F)Cl
    InChIKey
    NMEUKWOOQOHUNA-UHFFFAOYSA-N
    InChI
    1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)
    同義語
    DTXSID20946032 | 4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile | 4-(3...
  3. MK2-IN-3, Inhibitor of MAPK activated protein kinase 2;Inhibitor of MAPK activated protein kinase 3;Inhibitor of MAPK activated protein kinase 5
    CAS: 724711-21-1 分子式: C21H16N4O 分子量: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: M333061
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    技術識別子
    IUPAC名
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
    InChIKey
    OWFLADWRSCINST-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
    同義語
    1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one | MK2 Inhibitor III
  4. Quazinone (Ro 13-6438)
    CAS: 70018-51-8 PubChem CID: 135418296 分子式: C11H10ClN3 分子量: 235.67
    ◐ .受注生産 · 8~12週間 商品 #: Q336048
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    技術識別子
    IUPAC名
    (3R)-6-chloro-3-methyl-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one
    SMILES
    CC1C(=O)NC2=NC3=C(CN12)C(=CC=C3)Cl
    InChIKey
    BHZFZYLBVSWUMT-ZCFIWIBFSA-N
    InChI
    1S/C11H10ClN3O/c1-6-10(16)14-11-13-9-4-2-3-8(12)7(9)5-15(6)11/h2-4,6H,5H2,1H3,(H,13,14,16)/t6-/m1/s1
    同義語
    Quazinona | Ro 13-6438; Ro 13-6438/006 | (3R)-6-chloro-3-methyl-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one | QUAZ...
  5. CMPD-1, Inhibitor of MAPK activated protein kinase 2
    CAS: 41179-33-3 分子式: C22H20FNO2 分子量: 349.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● 在庫あり — 米国 商品 #: C286549
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    技術識別子
    IUPAC名
    4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide
    SMILES
    C1=CC=C(C(=C1)C2=CC=C(C=C2)CCCC(=O)NC3=CC=C(C=C3)O)F
    InChIKey
    ODYAQBDIXCVKAE-UHFFFAOYSA-N
    InChI
    1S/C22H20FNO2/c23-21-6-2-1-5-20(21)17-10-8-16(9-11-17)4-3-7-22(26)24-18-12-14-19(25)15-13-18/h1-2,5-6,8-15,25H,3-4,7H2,(H,24,26)
    同義語
    4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide | EX-A7609 | AKOS024456977 | GTPL6009 | MAPKAPK2a Inhibito...
  6. MK-2 Inhibitor III
    CAS: 1186648-22-5 PubChem CID: 25163932 分子式: C21H16N4O・H2O 分子量: 358.39
    ◐ .受注生産 · 8~12週間 商品 #: M334622
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    技術識別子
    IUPAC名
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;hydrate
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4.O
    InChIKey
    NIKCVKMHGQQSRN-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O.H2O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15;/h1-5,7,9-12,25H,6,8H2,(H,23,26);1H2
    同義語
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
  7. MK2 Inhibitor III, Inhibitor of MAPK activated protein kinase 2;Inhibitor of MAPK activated protein kinase 3;Inhibitor of MAPK activated protein kinase 5
    CAS: 724711-21-1 分子式: C21H16N4O 分子量: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● 在庫あり — 米国 商品 #: M425672
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    技術識別子
    IUPAC名
    2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
    SMILES
    C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
    InChIKey
    OWFLADWRSCINST-UHFFFAOYSA-N
    InChI
    1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
    同義語
    1,5,6,7-Tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one
  8. PF 3644022, Inhibitor of MAPK activated protein kinase 2
    CAS: 1276121-88-0 PubChem CID: 44631903 分子式: C21H18N4OS 分子量: 374.46
    固体 Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● 在庫あり — 米国 商品 #: P288030
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    技術識別子
    IUPAC名
    (15R)-15-methyl-5-(6-methylpyridin-3-yl)-11-thia-6,14,17-triazatetracyclo[8.8.0.02,7.012,18]octadeca-1(10),2(7),3,5,8,12(18)-hexaen-13-one
    SMILES
    CC1CNC2=C(C(=O)N1)SC3=C2C4=C(C=C3)N=C(C=C4)C5=CN=C(C=C5)C
    InChIKey
    CMWRPDHVGMHLSZ-GFCCVEGCSA-N
    InChI
    1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1
    同義語
    (10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-on...
  9. Zunsemetinib
    CAS: 1640282-42-3 分子式: C25H22ClF2N5O3 分子量: 513.92
    固体 Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● 在庫あり — 米国 商品 #: Z614989
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    技術識別子
    IUPAC名
    3-chloro-4-[(3,5-difluoropyridin-2-yl)methoxy]-1-[2-[2-(2-hydroxypropan-2-yl)pyrimidin-4-yl]-5-methylpyridin-4-yl]-6-methylpyridin-2-one
    SMILES
    Cc1cc(OCc2ncc(F)cc2F)c(Cl)c(=O)n1c1cc(ncc1C)c1nc(ncc1)C(C)(C)O
    InChIKey
    FQPQMJULRZINPV-UHFFFAOYSA-N
    InChI
    1S/C25H22ClF2N5O3/c1-13-10-30-18(17-5-6-29-24(32-17)25(3,4)35)9-20(13)33-14(2)7-21(22(26)23(33)34)36-12-19-16(28)8-15(27)11-31-19/h5-11,35H,12H2,1-4H3
    同義語
    (1(2H),4'-Bipyridin)-2-one, 3-chloro-4-((3,5-difluoro-2-pyridinyl)methoxy)-2'-(2-(1-hydroxy-1-methylethyl)-4-pyrimidi...
  10. MK2-IN-1 hydrochloride
    CAS: 1314118-94-9 PubChem CID: 70681199 分子式: C27H26Cl2N4O2 分子量: 509.4
    ◐ .受注生産 · 8~12週間 商品 #: M651058
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    技術識別子
    IUPAC名
    5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide;hydrochloride
    SMILES
    C1CN(CCN1)C2=CC=C(C=C2)N(CC3=CC=CC=N3)C(=O)C4=CC=C(O4)C5=CC=C(C=C5)Cl.Cl
    InChIKey
    AZDOSXSDARWKGX-UHFFFAOYSA-N
    InChI
    1S/C27H25ClN4O2.ClH/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31;/h1-14,29H,15-19H2;1H
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よくある質問

Which compounds are listed for MAPKAPK2 (MK2)?
Compounds associated with MAPKAPK2 (MK2) are grouped here under the MAPK/ERK Pathway classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does MAPKAPK2 (MK2) sit within MAPK/ERK Pathway?
MAPKAPK2 (MK2) is one target listing within the MAPK/ERK Pathway classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from MAPKAPK2 (MK2)?
For compounds listed under MAPKAPK2 (MK2), check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for MAPKAPK2 (MK2)?
Browse the parent MAPK/ERK Pathway listing to reach targets neighbouring MAPKAPK2 (MK2), and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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