6-Propyl-2-thiouracil - Moligand™, ≥98% , CAS No.51-52-5
Non-competitive type I iodothyronine deiodinase inhibitor. Thyroperoxidase inhibitor.
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Non-competitive type I iodothyronine deiodinase inhibitor. Thyroperoxidase inhibitor.
6-PTU is a thiolated uracil derivativewhich has been shown to acts as an antihyperthyroid agent. 6-Propyl-2-thiouracil is known to inhibit the deiodination of thyroxine to triiodothyronine via deiodinase, iodothyronine, type I (DIO1).
It is a thyreostatic (thyroid hormone) agent that may be used as a reference material in thyreostatic drug separation and detection technologies such as capillary electrophoresis, HPLC, or gas chromatography.
| CAS | 51-52-5 |
|---|---|
| 동의어 | 6-PTU | BSPBio_000387 | PROPYLTHIOURACIL [IARC] | PROPYLTHIOURACIL [EP MONOGRAPH] | Propylthiouracil; 2,3-dihydro-6-propyl-2-thioxopyrimidin-4(1H)-one | Propylthiouracilum [INN-Latin] | 6-propyl-2-thioxo-1H-pyrimidin-4-one | AI3-25477 | Propylthiorit | Pr |
| 사양 및 순도 | Moligand™, ≥98% |
| 보관 조건 | Room temperature |
| 배송 | Normal |
| Product Description | 6-PTU is a thiolated uracil derivativewhich has been shown to acts as an antihyperthyroid agent. 6-Propyl-2-thiouracil is known to inhibit the deiodination of thyroxine to triiodothyronine via deiodinase, iodothyronine, type I (DIO1). |
| Pubchem Sid | 488191003 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191003 |
| 용해성 | Soluble in 10% ammonia, water (1.1 mg/ml) at 20 °C, DMSO, methanol, 1 N NaOH (50 mg/ml), aclcohol (16 mg/ml), and water (10 mg/ml,boiling). Insoluble in ether, chloroform, and benzene. |
| 감도 | light sensitive |
| Mdl 번호 | MFCD00006041 |
| EC 번호 | 200-103-2 |
| PubChem CID | 657298 |
| 분자 공식 | C7H10N2OS |