Reagents for Peptide Synthesis

Source reagents for peptide synthesis, coupling, protection, and sequence assembly. Use this page to compare building and workflow-support reagents for solid-phase and solution-phase peptide chemistry.

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

946 products

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  1. (S)-(+)-α-Aminocyclohexanepropionic acid hydrate
    CAS: 307310-72-1 Formula: C9H17NO2·xH2O Molecular Weight: 171.24
    In Stock Item #: I169446
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-cyclohexylpropanoic acid;hydrate
    SMILES
    C1CCC(CC1)CC(C(=O)O)N.O
    InChIKey
    HDJQIWAIDCEDEF-QRPNPIFTSA-N
    InChI
    1S/C9H17NO2.H2O/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h7-8H,1-6,10H2,(H,11,12);1H2/t8-;/m0./s1
    Synonyms
    (S)-(+)-alpha-Aminocyclohexanepropionic acid hydrate, technical grade | 3-Cyclohexyl-L-alanine hydrate | (S)-(+)-alph...
  2. (S)-(-)-1-Boc-2-tert-butyl-3-methyl-4-imidazolidinone
    CAS: 119838-38-9 Formula: C13H24N2O3 Molecular Weight: 256.34
    In Stock Item #: I166384
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    IUPAC Name
    tert-butyl (2S)-2-tert-butyl-3-methyl-4-oxoimidazolidine-1-carboxylate
    SMILES
    CC(C)(C)C1N(C(=O)CN1C(=O)OC(C)(C)C)C
    InChIKey
    HJJLVATZPPJBNG-JTQLQIEISA-N
    InChI
    1S/C13H24N2O3/c1-12(2,3)10-14(7)9(16)8-15(10)11(17)18-13(4,5)6/h10H,8H2,1-7H3/t10-/m0/s1
    Synonyms
    J-004208 | (2S)-2-(1,1-Dimethylethyl)-3-methyl-4-oxo-1-imidazolidinecarboxylic Acid 1,1-Dimethylethyl Ester | HJJLVAT...
  3. Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium hexafluorophosphate
    CAS: 164298-25-3 PubChem CID: 10935980 Formula: C9H16F7N2P Molecular Weight: 316.2
    Out of Stock Item #: F293014
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    IUPAC Name
    1-[fluoro(pyrrolidin-1-ium-1-ylidene)methyl]pyrrolidine;hexafluorophosphate
    SMILES
    C1CCN(C1)C(=[N+]2CCCC2)F.F[P-](F)(F)(F)(F)F
    InChIKey
    MNJUGQKOHJQOCK-UHFFFAOYSA-N
    InChI
    1S/C9H16FN2.F6P/c10-9(11-5-1-2-6-11)12-7-3-4-8-12;1-7(2,3,4,5)6/h1-8H2;/q+1;-1
    Synonyms
    1-[Fluoro(1-pyrrolidinyl)methylene]-1-pyrrolidinium Hexafluorophosphate(V) | 1-(Fluoro(pyrrolidin-1-yl)methylene)pyrr...
  4. Z-Gly-NH2
    CAS: 949-90-6 EC Number: 213-445-2 PubChem CID: 70366 Formula: C10H12N2O3 Molecular Weight: 208.21
    In Stock Item #: Z113949
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    IUPAC Name
    benzyl N-(2-amino-2-oxoethyl)carbamate
    SMILES
    C1=CC=C(C=C1)COC(=O)NCC(=O)N
    InChIKey
    HQYMUNCIMNFLDT-UHFFFAOYSA-N
    InChI
    1S/C10H12N2O3/c11-9(13)6-12-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H2,11,13)(H,12,14)
    Synonyms
    Benzyl carbamoylmethylcarbamate | NSC88477 | NSC-88477 | HQYMUNCIMNFLDT-UHFFFAOYSA-N | FT-0622827 | 6NLL3GNH3P | CARB...
  5. Z-Dehydro-Ala-OMe
    CAS: 21149-17-7 PubChem CID: 3525700 Formula: C12H13NO4 Molecular Weight: 235.24
    In Stock Item #: Z168546
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    IUPAC Name
    methyl 2-(phenylmethoxycarbonylamino)prop-2-enoate
    SMILES
    COC(=O)C(=C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    STFUIEDYPRMRNN-UHFFFAOYSA-N
    InChI
    1S/C12H13NO4/c1-9(11(14)16-2)13-12(15)17-8-10-6-4-3-5-7-10/h3-7H,1,8H2,2H3,(H,13,15)
    Synonyms
    A1-02629 | Z-Dehydroalanine methyl ester | N-carbobenzyloxydehydroalanine methyl ester | Z-Dehydro-Ala-OMe | A815167 ...
  6. Z-Dap(Fmoc)-OH
    CAS: 142855-80-9 PubChem CID: 2756241 Formula: C26H24N2O6 Molecular Weight: 460.48
    In Stock Item #: Z137464
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    IUPAC Name
    (2S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-2-(phenylmethoxycarbonylamino)propanoic acid
    SMILES
    C1=CC=C(C=C1)COC(=O)NC(CNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
    InChIKey
    MVKNXKRRMCSKJJ-QHCPKHFHSA-N
    InChI
    1S/C26H24N2O6/c29-24(30)23(28-26(32)33-15-17-8-2-1-3-9-17)14-27-25(31)34-16-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,27,31)show more
    Synonyms
    3-[5-(4-fluoro-phenyl)-furan-2-yl]-propionicacid | D-Alanine, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-N-[(phenylm...
  7. Fmoc-Nin-Boc-L-tryptophan pentafluorophenyl ester
    CAS: 181311-44-4 PubChem CID: 56777291 Formula: C37H29F5N2O6 Molecular Weight: 692.65
    Out of Stock Item #: F338864
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    IUPAC Name
    tert-butyl 3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propyl]indole-1-carboxylate
    SMILES
    CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CC(C(=O)OC3=C(C(=C(C(=C3F)F)F)F)F)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
    InChIKey
    IDYZGIYCOLJXRE-SANMLTNESA-N
    InChI
    1S/C37H29F5N2O6/c1-37(2,3)50-36(47)44-17-19(20-10-8-9-15-27(20)44)16-26(34(45)49-33-31(41)29(39)28(38)30(40)32(33)42)43-35(46)48-18-25-23-13-6-4-11-21show more
    Synonyms
    L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,3,4,5,6-pentafluorophenyl est...
  8. Z-Asp(OMe)-OH
    CAS: 3160-47-2 PubChem CID: 7014888 Formula: C13H15NO6 Molecular Weight: 281.26
    In Stock Item #: Z116867
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    IUPAC Name
    (2S)-4-methoxy-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
    SMILES
    COC(=O)CC(C(=O)O)NC(=O)OCC1=CC=CC=C1
    InChIKey
    PHMBNDDHIBIDRQ-JTQLQIEISA-N
    InChI
    1S/C13H15NO6/c1-19-11(15)7-10(12(16)17)14-13(18)20-8-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3,(H,14,18)(H,16,17)/t10-/m0/s1
    Synonyms
    N-Cbz-L-aspartic acid β-methyl ester Z-L-Aspartic acid 4-methyl ester
  9. Boc-Cys-OH
    CAS: 20887-95-0 Formula: C8H15NO4S Molecular Weight: 221.27
    In Stock Item #: B140877
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    IUPAC Name
    (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoic acid
    SMILES
    CC(C)(C)OC(=O)NC(CS)C(=O)O
    InChIKey
    ATVFTGTXIUDKIZ-YFKPBYRVSA-N
    InChI
    1S/C8H15NO4S/c1-8(2,3)13-7(12)9-5(4-14)6(10)11/h5,14H,4H2,1-3H3,(H,9,12)(H,10,11)/t5-/m0/s1
    Synonyms
    Boc-L-cysteine|20887-95-0|Boc-Cys-OH|N-Boc-L-Cysteine|(R)-2-((TERT-BUTOXYCARBONYL)AMINO)-3-MERCAPTOPROPANOIC ACID|N-t...
  10. Boc-Phe(3-CF3)-OH
    CAS: 142995-31-1 Formula: C15H18F3NO4 Molecular Weight: 333.3
    In Stock Item #: B131975
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    Technical Identifiers
    IUPAC Name
    (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[3-(trifluoromethyl)phenyl]propanoic acid
    SMILES
    CC(C)(C)OC(=O)NC(CC1=CC(=CC=C1)C(F)(F)F)C(=O)O
    InChIKey
    SHMWDGGGZHFFRC-NSHDSACASA-N
    InChI
    1S/C15H18F3NO4/c1-14(2,3)23-13(22)19-11(12(20)21)8-9-5-4-6-10(7-9)15(16,17)18/h4-7,11H,8H2,1-3H3,(H,19,22)(H,20,21)/t11-/m0/s1
    Synonyms
    DTXSID70931711 | Boc-Phe(3-CF3)-OH, >=98.0% (TLC) | MFCD00672525 | (S)-2-((tert-Butoxycarbonyl)amino)-3-(3-(trifluoro...
  11. Z-D-Prolinol
    CAS: 72597-18-3 Formula: C13H17NO3 Molecular Weight: 235.28
    In Stock Item #: Z139224
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    Technical Identifiers
    IUPAC Name
    benzyl (2R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
    SMILES
    C1CC(N(C1)C(=O)OCC2=CC=CC=C2)CO
    InChIKey
    BJTNHGVCFWDNDP-GFCCVEGCSA-N
    InChI
    1S/C13H17NO3/c15-9-12-7-4-8-14(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12,15H,4,7-10H2/t12-/m1/s1
    Synonyms
    ghl.PD_Mitscher_leg0.192 | BJTNHGVCFWDNDP-GFCCVEGCSA-N | AB22120 | Benzyl (R)-2-hydroxymethylpyrrolidine-1-carboxylat...
  12. 4,4',4''-Tris(benzoyloxy)trityl Bromide [Hydroxyl Protecting Agent]
    CAS: 86610-66-4 PubChem CID: 3933738 Formula: C40H27BrO6 Molecular Weight: 683.55
    In Stock Item #: T162634
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    Technical Identifiers
    IUPAC Name
    [4-[bis(4-benzoyloxyphenyl)-bromomethyl]phenyl] benzoate
    SMILES
    C1=CC=C(C=C1)C(=O)OC2=CC=C(C=C2)C(C3=CC=C(C=C3)OC(=O)C4=CC=CC=C4)(C5=CC=C(C=C5)OC(=O)C6=CC=CC=C6)Br
    InChIKey
    PKXTVZCJOBWKIG-UHFFFAOYSA-N
    InChI
    1S/C40H27BrO6/c41-40(31-16-22-34(23-17-31)45-37(42)28-10-4-1-5-11-28,32-18-24-35(25-19-32)46-38(43)29-12-6-2-7-13-29)33-20-26-36(27-21-33)47-39(44)30-show more
    Synonyms
    Tris[4-(phenylcarbonyloxy)phenyl]methyl Bromide
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Frequently Asked Questions

How do I choose between Reagents for Peptide Synthesis variants?
Match reagent to substrate compatibility, required selectivity, scalability, and downstream purification needs. Different reagents for peptide synthesis have distinct reactivity profiles — review reaction conditions and reported yields for each variant.
What specifications matter for Reagents for Peptide Synthesis?
Purity, titer (for solution reagents), water content for moisture-sensitive reagents, stabilizer presence, and pack size. Always check certificate of analysis for batch-specific quality data.
How should Reagents for Peptide Synthesis be stored and handled?
Many synthesis reagents are moisture- or air-sensitive. Store in sealed containers under inert atmosphere when specified. Solution reagents may degrade after multiple openings — aliquot for long-term storage.
Are research and process scales both available?
Yes. Reagents for Peptide Synthesis are available in gram-scale research quantities through kilogram-scale process supplies. Bulk packaging and custom synthesis options are available on request.

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