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CDK9-IN-19 is a highly potent and selective CDK9 inhibitor with an IC 50 value of 2.0 nM. CDK9-IN-19 has excellent cellular antiproliferative activity, moderate pharmacokinetic property and low hERG inhibition. CDK9-IN-19 significantly induces tumour growth inhibition in an MV4-11 xenograft mice model. CDK9-IN-19 can be used for researching acute myeloid leukaemia (AML).
| CAS | 2479306-60-8 |
|---|---|
| 보관 조건 | Store at -20°C |
| 배송 | Ice chest + Ice pads |
| Product Description | CDK9-IN-19 is a highly potent and selective CDK9 inhibitor with an IC 50 value of 2.0 nM. CDK9-IN-19 has excellent cellular antiproliferative activity, moderate pharmacokinetic property and low hERG inhibition. CDK9-IN-19 significantly induces tumour growth inhibition in an MV4-11 xenograft mice model. CDK9-IN-19 can be used for researching acute myeloid leukaemia (AML). |