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W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid , and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU. W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation , including the IL6-JAK-STAT3 pathway and the ferroptosis pathway.
| CAS | W1424691 |
|---|---|
| 사양 및 순도 | ≥99% |
| 보관 조건 | Store at 2-8°C |
| 배송 | Wet ice |
| Product Description | W1131 TFA is a potent STAT3 inhibitor that induces ferroptosis. W1131 inhibits cancer progression in subcutaneous xenograft, organoid , and PDX models of gastric cancer. W1131 effectively alleviates cancer cell chemoresistance to 5-FU. W1131 regulates the cell cycle, DNA damage response, and oxidative phosphorylation , including the IL6-JAK-STAT3 pathway and the ferroptosis pathway. |