Carbazole - ≥96% , CAS No.86-74-8

CAS: 86-74-8 Cat. No.: C104875 Fórmula: C₁₂H₉N Peso molecular: 167.21 Beilstein Registry Number: 3956 Número CE: 201-696-0

GRAU & PUREZA ≥96%

Synonyms

9-H-carbazole | 9H-Carbazole | C3722 | Dibenzo(b,d)pyrrole | CAS-86-74-8 | HSDB 2164 | DTXSID4020248 | para-carbazole | NCGC00256533-01 | 9-Azafluorene | Chlorophenesin carbamate | NSC3498 | NSC-3498 | Carbazole, >=95% (GC) | CCRIS 121 | CARBAZOLE | Carba

Storage

Room temperature

Shipped In

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Visão geral

Carbazole is an aromatic heterocyclic organic molecule. It mainly interacts with DNA and damages it. These events suppress the synthesis of new DNA or RNA. Carbazole derivatives are involved in antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidant, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective and pancreatic lipase suppression activities.
Carbazole has been used in the uronic acid assay

Especificações

Sinónimos

9-H-carbazole | 9H-Carbazole | C3722 | Dibenzo(b,d)pyrrole | CAS-86-74-8 | HSDB 2164 | DTXSID4020248 | para-carbazole | NCGC00256533-01 | 9-Azafluorene | Chlorophenesin carbamate | NSC3498 | NSC-3498 | Carbazole, >=95% (GC) | CCRIS 121 | CARBAZOLE | Carba

Especificações e pureza

≥96%

Condições de armazenamento de armazenamento

Room temperature

Enviado em

FedEx DG Service

Pureza

≥96%

Nomes e identificadores

Pubchem Sid

488180177

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180177

Sorrisos canónicos

C1=CC=C2C(=C1)C3=CC=CC=C3N2

IUPAC Name

9H-carbazole

InChIKey

UJOBWOGCFQCDNV-UHFFFAOYSA-N

INCHI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

SMILES isoméricas

C1=CC=C2C(=C1)C3=CC=CC=C3N2

WGK Alemanha

2

RTECS

FE3150000

Número UN

3077

Grupo de embalagem

III

Peso molecular

167.21

Beilstein

3956

Reaxy-Rn

3956

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3956&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Indoles and derivatives
      • Subclass Carbazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Indoles and derivatives
• Subclass: Carbazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Carbazoles
• Alternative Parents: Indoles Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Carbazole - Indole - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
• External Descriptors: a carbazole

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

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TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

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PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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U-937 (7138 Activities)

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KIF11 Tchem Kinesin-like protein 1 (1720 Activities)

Discover Target: KIF11

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HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

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Alvos associados (não humanos)

Staphylococcus aureus (210822 Activities)

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Bovine viral diarrhea virus 1 (1277 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

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clpP ATP-dependent Clp protease proteolytic subunit (245 Activities)

Discover Target: clpP

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Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: It is insoluble in water;Solubility in hot EtOH:almost transparency
• Ponto de inflamação (°F): 428℉
• Ponto de inflamação (°C): 220°C
• Ponto de ebulição (°C): 355°C
• Ponto de fusão (°C): 245°C
• Peso molecular: 167.210 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 167.073 Da
• Monoisotopic Mass: 167.073 Da
• Topological Polar Surface Area: 15.800 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 170.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1