G Protein-Coupled Receptors

G protein–coupled receptors (GPCRs) are a large class of cell-surface receptors with a seven-transmembrane architecture and constitute one of the largest membrane receptor families known to date. In the human genome, genes encoding GPCRs account for roughly 4% of all protein-coding genes; ...

Somatostatin is an important regulatory peptide, widely distributed in the central nervous system, endocrine glands, and gastrointestinal tract.

The term "IDG families" likely refers to the Illuminating the Druggable Genome (IDG) project, which is a part of the broader NIH Common Fund's effort to explore and better understand the human genome, specifically focusing on the "druggable" portion of the genome.