IXA4 - Moligand™, ≥98% , CAS No.1185329-96-7

CAS: 1185329-96-7 Cat. No.: I651766 Fórmula: C₂₄H₂₈N₄O₄ Peso molecular: 436.50 Número CE: 840-577-3 PubChem CID: 26357859

GRAU & PUREZA Moligand™, ≥98%

Synonyms

N-(1-(2-(Methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation.

Especificações

Sinónimos

N-(1-(2-(Methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide

Especificações e pureza

Moligand™, ≥98%

Mecanismos bioquímicos e fisiológicos

IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stre

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

INHIBITOR

Pureza

≥98%

Nomes e identificadores

SMILES isoméricas

CC1=CC=C(C=C1)OCCN(C)C(=O)CN2C=C(C=N2)NC(=O)CCOC3=CC=CC=C3

PubChem CID

26357859

Peso molecular

436.50

Propriedades químicas e físicas

• Solubilidade: DMSO : 100 mg/mL (229.10 mM; Need ultrasonic)
• Peso molecular: 436.500 g/mol
• XLogP3: 2.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 436.211 Da
• Monoisotopic Mass: 436.211 Da
• Topological Polar Surface Area: 85.700 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 576.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1