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  1. AZD 5582 dihydrochloride
    CAS: 1883545-51-4 PubChem CID: 90489014 Fórmula: C58H78N8O8.2HCl Peso molecular: 1088.21
    ◐ .Sob encomenda · 8–12 semanas Item #: A288309
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    Nome IUPAC
    (2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more
    SMILES
    CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC.Cl.Cl
    InChIKey
    DAILKFFMJFAUCE-GXSVUDMFSA-N
    InChI
    1S/C58H78N8O8.2ClH/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-4show more
    Sinónimos
    3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylg...
  2. UC 112
    CAS: 383392-66-3 PubChem CID: 3426979 Fórmula: C22H24N2O2 Peso molecular: 348.44
    ● Em estoque — EUA Item #: U288560
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    Identificadores técnicos
    Nome IUPAC
    5-(phenylmethoxymethyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol
    SMILES
    C1CCN(C1)CC2=CC(=C3C=CC=NC3=C2O)COCC4=CC=CC=C4
    InChIKey
    LTGLGIQQZXSLLF-UHFFFAOYSA-N
    InChI
    1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3,6-10,13,25H,4-5,11-12,14-16H2
    Sinónimos
    5-((benzyloxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol | 5-[(Phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-q...
  3. LCL161, Inhibitor of baculoviral IAP repeat containing 2;Inhibitor of X-linked inhibitor of apoptosis
    CAS: 1005342-46-0 Fórmula: C26H33FN4O3S Peso molecular: 500.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Em estoque — EUA Item #: L127178
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    Nome IUPAC
    (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide
    SMILES
    CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC
    InChIKey
    UFPFGVNKHCLJJO-SSKFGXFMSA-N
    InChI
    1S/C26H33FN4O3S/c1-16(28-2)24(33)30-22(17-7-4-3-5-8-17)26(34)31-14-6-9-21(31)25-29-20(15-35-25)23(32)18-10-12-19(27)13-11-18/h10-13,15-17,21-22,28H,3-show more
    Sinónimos
    LCL 161 [WHO-DD] | (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoet...
  4. A 410099.1
    CAS: 762274-58-8 PubChem CID: 131858992 Fórmula: C27H40N4O3·HCl Peso molecular: 505.09
    ◐ .Sob encomenda · 8–12 semanas Item #: A287066
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    SMILES
    CN[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H]2CCCC3=CC=CC=C23)=O)=O)C4CCCCC4)=O)C.Cl
    InChIKey
    OPCYOBWCDDJCFT-VOSOYEAFSA-N
    Sinónimos
    Cloridrato de N-metil-L-alanil-(2S)-2-ciclohexilglicil-N-[(1R)-1,2,3,4-tetrahidro-1-naftalenil]-L-prolinamida
  5. GDC-0152, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of baculoviral IAP repeat containing 7;Antagonist of X-linked inhibitor of apoptosis
    CAS: 873652-48-3 Fórmula: C25H34N6O3S Peso molecular: 498.64
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: G129293
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    Nome IUPAC
    (2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide
    SMILES
    CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC
    InChIKey
    WZRFLSDVFPIXOV-LRQRDZAKSA-N
    InChI
    1S/C25H34N6O3S/c1-16(26-2)22(32)27-21(18-12-7-4-8-13-18)25(34)31-15-9-14-19(31)23(33)28-24-20(29-30-35-24)17-10-5-3-6-11-17/h3,5-6,10-11,16,18-19,21,2show more
    Sinónimos
    AC-32972 | Z2235802113 | A14135 | L-PROLINAMIDE, N-METHYL-L-ALANYL-(2S)-2-CYCLOHEXYLGLYCYL-N-(4-PHENYL-1,2,3-THIADIAZ...
  6. AT406 (SM-406), Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
    CAS: 1071992-99-8 Fórmula: C32H43N5O4 Peso molecular: 561.71
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: A126412
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    Nome IUPAC
    (5S,8S,10aR)-N-benzhydryl-5-[[(2S)-2-(methylamino)propanoyl]amino]-3-(3-methylbutanoyl)-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocineshow more
    SMILES
    CC(C)CC(=O)N1CCC2CCC(N2C(=O)C(C1)NC(=O)C(C)NC)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4
    InChIKey
    LSXUTRRVVSPWDZ-MKKUMYSQSA-N
    InChI
    1S/C32H43N5O4/c1-21(2)19-28(38)36-18-17-25-15-16-27(37(25)32(41)26(20-36)34-30(39)22(3)33-4)31(40)35-29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-14,21-show more
    Sinónimos
    Iap inhibitor AT-406 | Debio 1143 | D 1143 | SM 406 | 1071992-99-8 | EX-A104 | GTPL7729 | NSC764757 | NSC-764757 | (5...
  7. Birinapant, cIAP1/cIAP2 inhibitor
    CAS: 1260251-31-7 Fórmula: C42H56F2N8O6 Peso molecular: 806.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: B129259
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    Nome IUPAC
    (2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methylshow more
    SMILES
    CCC(C(=O)N1CC(CC1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)O)NC(=O)C(C)NC
    InChIKey
    PKWRMUKBEYJEIX-DXXQBUJASA-N
    InChI
    1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-show more
    Sinónimos
    2,2-dimethyl-3-hydroxypropyl 2,2-dimethyl-3-hydroxypropionate | NSC767128 | NSC-767128 | D10417 | HY-16591 | (2S)-N-[...
  8. 4-Methylsalicylic acid
    CAS: 50-85-1 Número CE: 200-068-3 Fórmula: C8H8O3 Peso molecular: 152.15
    ● Em estoque — EUA Item #: M111847
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    Identificadores técnicos
    Nome IUPAC
    2-hydroxy-4-methylbenzoic acid
    SMILES
    CC1=CC(=C(C=C1)C(=O)O)O
    InChIKey
    NJESAXZANHETJV-UHFFFAOYSA-N
    InChI
    1S/C8H8O3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)
    Sinónimos
    2-Hydroxy-4-methylbenzoicacid | gamma-Cresotic acid | HY-78144 | 4-Methyl-2-hydroxybenzoic acid | 4-Methylsalicylate ...
  9. 4-Methylsalicylic acid
    CAS: 50-85-1 Número CE: 200-068-3 Fórmula: C8H8O3 Peso molecular: 152.15
    10mM in DMSO
    ◐ .Sob encomenda · 8–12 semanas Item #: M424376
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    Nome IUPAC
    2-hydroxy-4-methylbenzoic acid
    SMILES
    CC1=CC(=C(C=C1)C(=O)O)O
    InChIKey
    NJESAXZANHETJV-UHFFFAOYSA-N
    InChI
    1S/C8H8O3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)
    Sinónimos
    2-Hydroxy-4-methylbenzoicacid | gamma-Cresotic acid | HY-78144 | 4-Methyl-2-hydroxybenzoic acid | 4-Methylsalicylate ...
  10. AZD5582, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
    CAS: 1258392-53-8 Fórmula: C58H78N8O8 Peso molecular: 1015.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    ◐ .Sob encomenda · 8–12 semanas Item #: A421087
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    Nome IUPAC
    (2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more
    SMILES
    CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC
    InChIKey
    WLMCRYCCYXHPQF-ZVMUOSSASA-N
    InChI
    1S/C58H78N8O8/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-48-36-show more
    Sinónimos
    L-​Prolinamide,3,​3'-​[2,​4-​hexadiyne-​1,​6-​diylbis[oxy[(1S,​2R)​-​2,​3-​dihydro-​1H-​indene-​2,​1-​diyl]​]​]​bis[N-�...
  11. AZD5582, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
    CAS: 1258392-53-8 Fórmula: C58H78N8O8 Peso molecular: 1015.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: A413749
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    Identificadores técnicos
    Nome IUPAC
    (2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more
    SMILES
    CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC
    InChIKey
    WLMCRYCCYXHPQF-ZVMUOSSASA-N
    InChI
    1S/C58H78N8O8/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-48-36-show more
    Sinónimos
    3,3′-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylg...
  12. Birinapant, cIAP1/cIAP2 inhibitor
    CAS: 1260251-31-7 Fórmula: C42H56F2N8O6 Peso molecular: 806.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● Em estoque — EUA Item #: B421093
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    Preços e tamanhos do pacote
    Identificadores técnicos
    Nome IUPAC
    (2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methylshow more
    SMILES
    CCC(C(=O)N1CC(CC1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)O)NC(=O)C(C)NC
    InChIKey
    PKWRMUKBEYJEIX-DXXQBUJASA-N
    InChI
    1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-show more
    Sinónimos
    2,2-dimethyl-3-hydroxypropyl 2,2-dimethyl-3-hydroxypropionate | NSC767128 | NSC-767128 | D10417 | HY-16591 | (2S)-N-[...
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Perguntas frequentes

How is the IAP listing put together?
It draws on reported IAP annotations within Apoptosis and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IAP modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IAP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IAP compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IAP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IAP compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IAP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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