ROCK

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  1. GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    CAS: 850664-21-0 Fórmula: C29H30N8O5 Peso molecular: 570.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: G287476
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    Nome IUPAC
    N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
    SMILES
    CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
    InChIKey
    YOVNFNXUCOWYSG-UHFFFAOYSA-N
    InChI
    1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/show more
    Sinónimos
    GTPL8037 | NSC-767348 | SCHEMBL1838346 | UNII-F89KMM7TE2 | N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo...
  2. Narciclasine
    CAS: 29477-83-6 Fórmula: C14H13NO7 Peso molecular: 307.26
    ● Em estoque — EUA Item #: N125921
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    Nome IUPAC
    (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one
    SMILES
    C1OC2=C(O1)C(=C3C(=C2)C4=CC(C(C(C4NC3=O)O)O)O)O
    InChIKey
    LZAZURSABQIKGB-AEKGRLRDSA-N
    InChI
    1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1
    Sinónimos
    Lycoricidin-A | MFCD01729949 | [1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-,...
  3. GSK429286A, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of ribosomal protein S6 kinase A1
    CAS: 864082-47-3 Número CE: 689-442-9 Fórmula: C21H16F4N4O2 Peso molecular: 432.37
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: G127028
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    Nome IUPAC
    N-(6-fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide
    SMILES
    CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F
    InChIKey
    OLIIUAHHAZEXEX-UHFFFAOYSA-N
    InChI
    1S/C21H16F4N4O2/c1-10-19(20(31)28-17-6-12-9-26-29-16(12)8-15(17)22)14(7-18(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-6,8-9,14H,7H2,1H3,(H,26,29)(H,27,3show more
    Sinónimos
    HMS3244C08 | HMS3654N12 | N6-ethanimidoyl-L-lysine dihydrochloride | dihydropyridone indazole amide 15 | HY-11000 | N...
  4. OXA 06 dihydrochloride
    CAS: 1825455-91-1 PubChem CID: 91691120 Fórmula: C21H18FN3.2HCl Peso molecular: 404.31
    ● Em estoque — EUA Item #: O288636
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    Nome IUPAC
    N-[(2-fluorophenyl)methyl]-1-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methanamine;dihydrochloride
    SMILES
    C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl
    InChIKey
    ZRBCUSMZOWMVJS-UHFFFAOYSA-N
    InChI
    1S/C21H18FN3.2ClH/c22-20-4-2-1-3-17(20)14-23-13-15-5-7-16(8-6-15)18-9-11-24-21-19(18)10-12-25-21;;/h1-12,23H,13-14H2,(H,24,25);2*1H
    Sinónimos
    2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride
  5. 5-(Piperazina-1-ilsulfonil)isoquinolina
    CAS: 84468-24-6 Número CE: 635-920-7 Fórmula: C13H15N3O2S Peso molecular: 277.34
    ● Em estoque — EUA Item #: H275141
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    Nome IUPAC
    5-piperazin-1-ylsulfonylisoquinoline
    SMILES
    C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
    InChIKey
    UPTYCYWTFGTCCG-UHFFFAOYSA-N
    InChI
    1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2
    Sinónimos
    1-(5-Isoquinolinesulfonyl)piperazine | Piperazine, 1-(5-isoquinolinylsulfonyl)- | BDBM15203 | MFCD00209852 | NCGC0002...
  6. Valeric acid
    CAS: 109-52-4 Número CE: 203-677-2 PubChem CID: 7991 Fórmula: C5H10O2 Peso molecular: 102.13
    Líquido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(GC)
    ● Em estoque — EUA Item #: V108272
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    Identificadores técnicos
    Nome IUPAC
    pentanoic acid
    SMILES
    CCCCC(=O)O
    InChIKey
    NQPDZGIKBAWPEJ-UHFFFAOYSA-N
    InChI
    1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
    Sinónimos
    n-Valeric acid | Pentanoic Acid
  7. Valeric acid
    CAS: 109-52-4 Número CE: 203-677-2 PubChem CID: 7991 Fórmula: C5H10O2 Peso molecular: 102.13
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. CP ? Chemically Pure grade — moderate purity above technical grade but below analytical. Use for general lab reactions where ultra-low impurities aren't critical. ≥98%
    ● Em estoque — EUA Item #: V108270
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    Preços e tamanhos do pacote
    Identificadores técnicos
    Nome IUPAC
    pentanoic acid
    SMILES
    CCCCC(=O)O
    InChIKey
    NQPDZGIKBAWPEJ-UHFFFAOYSA-N
    InChI
    1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
    Sinónimos
    Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
  8. AS 1892802
    CAS: 928320-12-1 Fórmula: C20H19N3O2 Peso molecular: 333.38
    ● Em estoque — EUA Item #: A288609
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    Nome IUPAC
    1-[(1S)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
    SMILES
    C1=CC=C(C=C1)C(CO)NC(=O)NC2=CC=C(C=C2)C3=CC=NC=C3
    InChIKey
    WDTFYYZHMRBVHK-LJQANCHMSA-N
    InChI
    1S/C20H19N3O2/c24-14-19(17-4-2-1-3-5-17)23-20(25)22-18-8-6-15(7-9-18)16-10-12-21-13-11-16/h1-13,19,24H,14H2,(H2,22,23,25)/t19-/m1/s1
    Sinónimos
    N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea | (S,Z)-N'-(2-hydroxy-1-phenylethyl)-N-(4-(pyridin-4...
  9. RKI 1447 dihydrochloride
    CAS: 1782109-09-4 PubChem CID: 90489001 Fórmula: C16H14N4O2S.2HCl Peso molecular: 399.29
    Sólido ≥99%(HPLC)
    ● Em estoque — EUA Item #: R287461
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    Nome IUPAC
    1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea;dihydrochloride
    SMILES
    C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3.Cl.Cl
    InChIKey
    GBXLRAPHQIRDNS-UHFFFAOYSA-N
    InChI
    1S/C16H14N4O2S.2ClH/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12;;/h1-8,10,21H,9H2,(H2,18,19,20,22);2*1H
    Sinónimos
    N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride | 7-Chloro-5-(1H-pyrrol-2-yl)-1H-ben...
  10. Fasudil Hydrochloride
    CAS: 105628-07-7 Número CE: 805-833-0 Fórmula: C14H17N3O2S·HCl Peso molecular: 327.83
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: F122336
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    Nome IUPAC
    5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
    SMILES
    C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
    InChIKey
    LFVPBERIVUNMGV-UHFFFAOYSA-N
    InChI
    1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H
    Sinónimos
    5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline hydrochloride | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline hydrochloride |...
  11. SR 3677
    CAS: 1072959-67-1 Número CE: 802-637-7 PubChem CID: 25093235 Fórmula: C22H24N4O4 Peso molecular: 408.45
    ● Em estoque — EUA Item #: S288304
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    Nome IUPAC
    N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
    SMILES
    CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3
    InChIKey
    OQWZIAVXCYIZNN-UHFFFAOYSA-N
    InChI
    1S/C22H24N4O4/c1-26(2)9-10-28-20-11-15(16-12-23-24-13-16)7-8-17(20)25-22(27)21-14-29-18-5-3-4-6-19(18)30-21/h3-8,11-13,21H,9-10,14H2,1-2H3,(H,23,24)(Hshow more
    Sinónimos
    N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamide dihydrochloride
  12. Valeric acid
    CAS: 109-52-4 Número CE: 203-677-2 PubChem CID: 7991 Fórmula: C5H10O2 Peso molecular: 102.13
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● Em estoque — EUA Item #: V108271
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    Preços e tamanhos do pacote
    Identificadores técnicos
    Nome IUPAC
    pentanoic acid
    SMILES
    CCCCC(=O)O
    InChIKey
    NQPDZGIKBAWPEJ-UHFFFAOYSA-N
    InChI
    1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
    Sinónimos
    Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
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Perguntas frequentes

Which compounds are listed for ROCK?
Compounds associated with ROCK are grouped here under the Cytoskeleton classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does ROCK sit within Cytoskeleton?
ROCK is one target listing within the Cytoskeleton classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from ROCK?
For compounds listed under ROCK, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for ROCK?
Browse the parent Cytoskeleton listing to reach targets neighbouring ROCK, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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