NF-κB - Keap1-Nrf2 Supplier | High Purity

Produtos populares

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Sericic acid
CAS: 55306-03-1 PubChem CID: 124214 Fórmula: C₃₀H₄₈O₆ Peso molecular: 504.7

≥95%

◐ .Sob encomenda · 8–12 semanas Item #: S329534
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Nome IUPAC

(1S,4aR,6aR,6aS,6bR,8aR,9S,10R,11R,12aR,14bS)-1,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetrshow more

SMILES

CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1O)C)C(=O)O)C

InChIKey
IFIQVSCCFRXSJV-GOVAGAJPSA-N

InChI

1S/C30H48O6/c1-25(2)11-13-30(24(35)36)14-12-28(5)17(21(30)23(25)34)7-8-20-26(3)15-18(32)22(33)27(4,16-31)19(26)9-10-29(20,28)6/h7,18-23,31-34H,8-16H2,show more

Sinónimos
Olean-12-en-28-oic acid, 2,3,19,23-tetrahydroxy-, (2alpha,3beta,4beta,19alpha)- | SCHEMBL5799851 | AKOS040763084 | Se...
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Swertiamarine
CAS: 17388-39-5 PubChem CID: 442435 Fórmula: C₁₆H₂₂O₁₀ Peso molecular: 374.34

Sólido Analytical standard ? Moligand™ ? ≥98%

● Em estoque — EUA Item #: S110090
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Nome IUPAC

(3S,4R,4aR)-4-ethenyl-4a-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one

SMILES

C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O

InChIKey
HEYZWPRKKUGDCR-QBXMEVCASA-N

InChI

1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,1show more

Sinónimos
A811580 | Swertiamarin, >=95% (LC/MS-ELSD) | 1H,3H-Pyrano(3,4-c)pyran-1-one, 5-ethenyl-6-(beta-D-glucopyranosyloxy)-4...
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Cryptochlorogenic acid
CAS: 905-99-7 Fórmula: C₁₆H₁₈O₉ Peso molecular: 354.31

Sólido Analytical standard ? Moligand™ ?

● Em estoque — EUA Item #: C117944
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Nome IUPAC

(3R,5R)-4-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,3,5-trihydroxycyclohexane-1-carboxylic acid

SMILES

C1C(C(C(CC1(C(=O)O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O

InChIKey
GYFFKZTYYAFCTR-AVXJPILUSA-N

InChI

1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(21)25-14-11(19)6-16(24,15(22)23)7-12(14)20/h1-5,11-12,14,17-20,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14?,16?/m1/show more

Sinónimos
Cinnamic acid, 3,4-dihydroxy-, 4-carboxy-2,4,6-trihydroxycyclohexyl ester | Cyclohexanecarboxylic acid, 4-((3-(3,4-di...
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Gingerenone A
CAS: 128700-97-0 Fórmula: C₂₁H₂₄O₅ Peso molecular: 356.41

≥98%

● Em estoque — EUA Item #: G355262
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(E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one

SMILES

COC1=C(C=CC(=C1)CCC=CC(=O)CCC2=CC(=C(C=C2)O)OC)O

InChIKey
FWDXZNKYDTXGOT-GQCTYLIASA-N

InChI

1S/C21H24O5/c1-25-20-13-15(8-11-18(20)23)5-3-4-6-17(22)10-7-16-9-12-19(24)21(14-16)26-2/h4,6,8-9,11-14,23-24H,3,5,7,10H2,1-2H3/b6-4+

Sinónimos
FWDXZNKYDTXGOT-GQCTYLIASA-N | (E)-Gingerenone A | DTXSID50873741 | HY-120912 | (4E)-1,7-bis(4-hydroxy-3-methoxyphenyl...
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Eriodictyol 7-O-β-D-glucopyranoside
CAS: 38965-51-4 Fórmula: C₂₁H₂₂O₁₁ Peso molecular: 450.39

≥99%(HPLC)

◐ .Sob encomenda · 8–12 semanas Item #: E170077
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Nome IUPAC

(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one

SMILES

C1C(OC2=CC(=CC(=C2C1=O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC(=C(C=C4)O)O

InChIKey
RAFHNDRXYHOLSH-SFTVRKLSSA-N

InChI

1S/C21H22O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-5,14,16,18-25,27-29H,6-7H2/t14-,16+,show more

Sinónimos
(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydr...
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Resveratrol, Inhibitor of COX-2;Agonist of TAS2R14;Antagonist of Peroxisome proliferator-activated receptor-γ
CAS: 501-36-0 Número CE: 610-504-8 Fórmula: C₁₄H₁₂O₃ Peso molecular: 228.24

Sólido Analytical standard ? Moligand™ ?

● Em estoque — EUA Item #: R107314
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Nome IUPAC

5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

SMILES

C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O

InChIKey
LUKBXSAWLPMMSZ-OWOJBTEDSA-N

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

Sinónimos
Q369O8926L | CHEBI:27881 | CU-01000001503-3 | HMS1792H15 | NSC133100 | BPBio1_000479 | NCGC00344093-09 | RESVERATROL ...
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(R)-Sulforaphane
CAS: 142825-10-3 Fórmula: C₆H₁₁NOS₂ Peso molecular: 177.29

Líquido Moligand™ ? ≥98%

● Em estoque — EUA Item #: R131741
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Nome IUPAC

1-isothiocyanato-4-[(R)-methylsulfinyl]butane

SMILES

CS(=O)CCCCN=C=S

InChIKey
SUVMJBTUFCVSAD-SNVBAGLBSA-N

InChI

1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3/t10-/m1/s1

Sinónimos
HY-13755A | 1-isothiocyanato-4-[(R)-methanesulfinyl]butane | 1-Propanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:...
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NK 252
CAS: 1414963-82-8 Fórmula: C₁₃H₁₁N₅O₃ Peso molecular: 285.26

≥98%(HPLC)

◐ .Sob encomenda · 8–12 semanas Item #: N287824
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Identificadores técnicos

Nome IUPAC

1-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]-3-(pyridin-2-ylmethyl)urea

SMILES

C1=CC=NC(=C1)CNC(=O)NC2=NN=C(O2)C3=CC=CO3

InChIKey
FNSCFQXZZNCDAI-UHFFFAOYSA-N

InChI

1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19)

Sinónimos
DTXSID301020703 | NCGC00387474-01 | 1-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]-3-(pyridin-2-ylmethyl)urea | N-[5-(2-Fura...
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Brusatol
CAS: 14907-98-3 Fórmula: C₂₆H₃₂O₁₁ Peso molecular: 520.53

≥95%(HPLC)

● Em estoque — EUA Item #: B167412
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Nome IUPAC

methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-10,15,16-trihydroxy-9,13-dimethyl-3-(3-methylbut-2-enoyloxy)-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.0show more

SMILES

CC1=C(C(=O)CC2(C1CC3C45C2C(C(C(C4C(C(=O)O3)OC(=O)C=C(C)C)(OC5)C(=O)OC)O)O)C)O

InChIKey
ZZZYHIMVKOHVIH-VILODJCFSA-N

InChI

1S/C26H32O11/c1-10(2)6-15(28)37-18-20-25-9-35-26(20,23(33)34-5)21(31)17(30)19(25)24(4)8-13(27)16(29)11(3)12(24)7-14(25)36-22(18)32/h6,12,14,17-21,29-3show more

Sinónimos
NSC 172924 | methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-10,15,16-trihydroxy-9,13-dimethyl-3-(3-methylbut-2-enoyloxy)...
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ML385, Inhibitor of nuclear factor; erythroid 2 like 2
CAS: 846557-71-9 Fórmula: C₂₉H₂₅N₃O₄S Peso molecular: 511.59

Moligand™ ? ≥99%

● Em estoque — EUA Item #: M304758
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Identificadores técnicos

Nome IUPAC

2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide

SMILES

CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C

InChIKey
LINHYWKZVCNAMQ-UHFFFAOYSA-N

InChI

1S/C29H25N3O4S/c1-17-5-3-4-6-22(17)28(34)32-12-11-20-15-21(8-9-23(20)32)27-18(2)37-29(31-27)30-26(33)14-19-7-10-24-25(13-19)36-16-35-24/h3-10,13,15H,1show more

Sinónimos
N-[4-[2,3-Dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide | 2-(Benzo[d]...
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Dimethyl fumarate, Kelch-like ECH-associated protein 1 inhibitor
CAS: 624-49-7 Número CE: 210-849-0 Fórmula: C₆H₈O₄ Peso molecular: 144.13

Moligand™ ? ≥97%

● Em estoque — EUA Item #: D106459
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Nome IUPAC

dimethyl (E)-but-2-enedioate

SMILES

COC(=O)C=CC(=O)OC

InChIKey
LDCRTTXIJACKKU-ONEGZZNKSA-N

InChI

1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+

Sinónimos
(E/Z)-Dimethyl fumarate | Allomaleic acid dimethyl ester | CCG-213618 | Dimethylfumarate | dimethyl-fumarate | 2-bute...
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Carnosol
CAS: 5957-80-2 Fórmula: C₂₀H₂₆O₄ Peso molecular: 330.42

≥98%

● Em estoque — EUA Item #: C122021
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Identificadores técnicos

Nome IUPAC

(1R,8S,10S)-3,4-dihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[6.6.2.01,10.02,7]hexadeca-2,4,6-trien-15-one

SMILES

CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O

InChIKey
XUSYGBPHQBWGAD-PJSUUKDQSA-N

InChI

1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1

Sinónimos
.alpha.-Farnesene isomer | DTXSID80904451 | TRANS-.BETA.-FARNESENE | 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,...

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Perguntas frequentes

How is the Keap1-Nrf2 listing put together?

It draws on reported Keap1-Nrf2 annotations within NF-κB and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a Keap1-Nrf2 modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Keap1-Nrf2 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for Keap1-Nrf2 compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Keap1-Nrf2 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the Keap1-Nrf2 compound I need is not listed?

Search by CAS number or SMILES first, since analogs of Keap1-Nrf2 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.