TGF-beta/Smad

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  1. SIS 3 Hydrochloride
    CAS: 521984-48-5 PubChem CID: 16079005 Fórmula: C28H27N3O3•HCl Peso molecular: 489.99
    ● Em estoque — EUA Item #: S276442
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    Nome IUPAC
    (E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;hydrochloride
    SMILES
    CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl
    InChIKey
    CDKIEBFIMCSCBB-CALJPSDSSA-N
    InChI
    1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,show more
    Sinónimos
    (E)-1-[6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-...
  2. Pirfenidona
    CAS: 53179-13-8 Número CE: 621-260-7 Fórmula: C12H11NO Peso molecular: 185.22
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(GC)
    ● Em estoque — EUA Item #: P129335
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    Nome IUPAC
    5-methyl-1-phenylpyridin-2-one
    SMILES
    CC1=CN(C(=O)C=C1)C2=CC=CC=C2
    InChIKey
    ISWRGOKTTBVCFA-UHFFFAOYSA-N
    InChI
    1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
    Sinónimos
    MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone ...
  3. Trimethylamine N-Oxide(TMANO)
    CAS: 1184-78-7 Número CE: 214-675-6 PubChem CID: 1145 Fórmula: C3H9NO Peso molecular: 75.11
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(T)
    ● Em estoque — EUA Item #: T162064
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    Nome IUPAC
    N,N-dimethylmethanamine oxide
    SMILES
    C[N+](C)(C)[O-]
    InChIKey
    UYPYRKYUKCHHIB-UHFFFAOYSA-N
    InChI
    1S/C3H9NO/c1-4(2,3)5/h1-3H3
    Sinónimos
    Trimethylamine oxide | NSC 408426 | MFCD00002048 | Trimethlamine-N-oxide | Triox | CHEBI:15724 | EN300-396337 | Trime...
  4. Neohesperidin
    CAS: 13241-33-3 Número CE: 236-216-9 Fórmula: C28H34O15 Peso molecular: 610.56
    Sólido Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● Em estoque — EUA Item #: N101968
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    Nome IUPAC
    (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more
    SMILES
    CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O
    InChIKey
    ARGKVCXINMKCAZ-UZRWAPQLSA-N
    InChI
    1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more
    Sinónimos
    (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
  5. Trimethylamine-d9 N-Oxide
    CAS: 1161070-49-0 PubChem CID: 71752814 Fórmula: C3D9NO Peso molecular: 84.17
    ● Em estoque — EUA Item #: T336882
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    Nome IUPAC
    1,1,1-trideuterio-N,N-bis(trideuteriomethyl)methanamine oxide
    SMILES
    C[N+](C)(C)[O-]
    InChIKey
    UYPYRKYUKCHHIB-GQALSZNTSA-N
    InChI
    1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3
    Sinónimos
    Trimethylamine N-oxide-d9 | Trimethylamine-d9 N-Oxide, 98 atom % D, 98% (CP) | 1,1,1-trideuterio-N,N-bis(trideuteriom...
  6. Asiaticoside
    CAS: 16830-15-2 Número CE: 240-851-7 Fórmula: C48H78O19 Peso molecular: 959.12
    Sólido Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: A111276
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    Nome IUPAC
    [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-show more
    SMILES
    CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O
    InChIKey
    WYQVAPGDARQUBT-FGWHUCSPSA-N
    InChI
    1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(show more
    Sinónimos
    (-)-SENECIONINE | NSC-36002 | (2alpha,3beta,4alpha)-2,3,23-TRIHYDROXYURS-12-EN-28-OIC ACID O-6-DEOXY-alpha-L-MANNOPYR...
  7. Ammothamnine
    CAS: 16837-52-8 Número CE: 605-514-4 Fórmula: C15H24N2O2 Peso molecular: 264.36
    ● Em estoque — EUA Item #: A111286
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    Nome IUPAC
    (1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
    SMILES
    C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
    InChIKey
    XVPBINOPNYFXID-LHDUFFHYSA-N
    InChI
    1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
    Sinónimos
    Pachycarpidine | BDBM50597716 | Oxymatrine | BBL030371 | MLS001215101 | rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodi...
  8. Alantolactone
    CAS: 546-43-0 Fórmula: C15H20O2 Peso molecular: 232.32
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥97%(HPLC)
    ● Em estoque — EUA Item #: A114070
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    Nome IUPAC
    (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one
    SMILES
    CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C
    InChIKey
    PXOYOCNNSUAQNS-AGNJHWRGSA-N
    InChI
    1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
    Sinónimos
    (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | Q21099633 | DT...
  9. Halofuginone hydrobromide
    CAS: 64924-67-0 Número CE: 694-602-6 Fórmula: C16H17BrClN3O3•HBr Peso molecular: 495.59
    Sólido ≥98%(HPLC)
    ● Em estoque — EUA Item #: H288889
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    Nome IUPAC
    7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrobromide
    SMILES
    C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br
    InChIKey
    SJUWEPZBTXEUMU-LDXVYITESA-N
    InChI
    1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1
    Sinónimos
    MFCD00017259 | RU-19110 (hydrobromide) | Halofuginone hydrobromide, (-)- | AMY26820 | HY-N1584A | AKOS015920268 | Hal...
  10. Kartogenin
    CAS: 4727-31-5 Fórmula: C20H15NO3 Peso molecular: 317.34
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Em estoque — EUA Item #: K134657
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    Nome IUPAC
    2-[(4-phenylphenyl)carbamoyl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O
    InChIKey
    SLUINPGXGFUMLL-UHFFFAOYSA-N
    InChI
    1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
    Sinónimos
    KGN | 2-[[1,1'-Biphenyl]-4-ylcarbamoyl]benzoic Acid | 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid | 4'-Phenyl-phthalanil...
  11. R 268712
    CAS: 879487-87-3 PubChem CID: 11703284 Fórmula: C20H18FN5O Peso molecular: 363.39
    ● Em estoque — EUA Item #: R286557
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    Identificadores técnicos
    Nome IUPAC
    2-[4-[2-fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol
    SMILES
    CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO
    InChIKey
    JQGOCCALXFSRHZ-UHFFFAOYSA-N
    InChI
    1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)
    Sinónimos
    SCHEMBL5198271 | C20H18FN5O | NCGC00387472-01 | 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-py...
  12. Neohesperidin
    CAS: 13241-33-3 Número CE: 236-216-9 Fórmula: C28H34O15 Peso molecular: 610.56
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● Em estoque — EUA Item #: N140716
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    Identificadores técnicos
    Nome IUPAC
    (2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more
    SMILES
    CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O
    InChIKey
    ARGKVCXINMKCAZ-UZRWAPQLSA-N
    InChI
    1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more
    Sinónimos
    (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
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Perguntas frequentes

Which compounds are listed for TGF-beta/Smad?
Compounds associated with TGF-beta/Smad are grouped here under the TGF-beta/Smad classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does TGF-beta/Smad sit within TGF-beta/Smad?
TGF-beta/Smad is one target listing within the TGF-beta/Smad classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from TGF-beta/Smad?
For compounds listed under TGF-beta/Smad, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for TGF-beta/Smad?
Browse the parent TGF-beta/Smad listing to reach targets neighbouring TGF-beta/Smad, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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