2′-Chloroacetophenone - 10mM in DMSO , CAS No.2142-68-9

CAS: 2142-68-9 Cat. No.: C660751 Molecular Weight: 154.59 Beilstein Registry Number: 1858916 EC Number: 218-397-6

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

2′-Chloroacetophenone undergoes stereoselective reduction to (R)-2′-chloro-1-phenyl-ethanol by Saccharomyces cerevisiae B5. It is commonly used as lacrimator.
2′-Chloroacetophenone was employed as model substrate to investigate the enzymatic performance of Aspergillus terreus and Rhizopus oryzae in enantioselective bioreductions using glycerol as a co-solvent.

Specifications

Specifications & Purity

10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CC(=O)C1=CC=CC=C1Cl
• WGK Germany: 3
• RTECS: AM6310000
• UN Number: 3416
• Molecular Weight: 154.59
• Beilstein: 1858916
• Reaxy-Rn: 1858916
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1858916&ln=

Chemical and Physical Properties

• Sensitivity: Lachrymatory
• Refractive Index: 1.5438
• Flash Point(°F): 197.6 °F
• Flash Point(°C): 92 °C
• Boil Point(°C): 229°C

References

1. Guo-Chao Xu, Yue Wang, Ming-Hui Tang, Jie-Yu Zhou, Jing Zhao, Rui-Zhi Han, Ye Ni.  (2018)  Hydroclassified Combinatorial Saturation Mutagenesis: Reshaping Substrate Binding Pockets of KpADH for Enantioselective Reduction of Bulky–Bulky Ketones.  ACS Catalysis,      [PMID:] [10.1021/acscatal.8b02286]