2-Hydroxyethyl methacrylate（HEMA） - anhydrous, ≥99%, Containing molecular sieves,with molecular sieves, stabilized with 200ppm MEHQ,Water≤50 ppm , CAS No.868-77-9

CAS: 868-77-9 Cat. No.: H140644 Formula: C₆H₁₀O₃ Molecular Weight: 130.14 Beilstein Registry Number: 1071580 EC Number: 212-782-2

GRADE & PURITY Anhydrous Grade, ≥99%, Containing molecular sieves,with molecular sieves, stabilized with 200ppm MEHQ,Water≤50 ppm

Synonyms

2-Hydroxyethyl 2-methylacrylate # | EN300-98188 | InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H | beta-Hydroxyethyl methacrylate | Methacrylic acid, 2-hydroxyethyl ester | 1,2-Ethanediol mono(2-methylpropenoate) | 2-Hydroxyethyl methacrylate (HEMA) |

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery.
HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers.It is also used to prepare light responsive membranes of PHEMA,HEMA/ acrylamide based specific drug release hydrogel,and water soluble HEMA/methacrylic acid hydrogel for drug delivery.Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.

Specifications

Synonyms

2-Hydroxyethyl 2-methylacrylate # | EN300-98188 | InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H | beta-Hydroxyethyl methacrylate | Methacrylic acid, 2-hydroxyethyl ester | 1,2-Ethanediol mono(2-methylpropenoate) | 2-Hydroxyethyl methacrylate (HEMA) |

Specifications & Purity

anhydrous, ≥99%, Containing molecular sieves,with molecular sieves, stabilized with 200ppm MEHQ,Water≤50 ppm

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Anhydrous Grade

Purity

≥99%

Names and Identifiers

Pubchem Sid

508814865

Canonical Smiles

CC(=C)C(=O)OCCO

IUPAC Name

2-hydroxyethyl 2-methylprop-2-enoate

InChIKey

WOBHKFSMXKNTIM-UHFFFAOYSA-N

INCHI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

Isomeric SMILES

CC(=C)C(=O)OCCO

WGK Germany

NWG

RTECS

OZ4725000

Molecular Weight

130.14

Beilstein

1071580

Reaxy-Rn

1071583

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071583&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Carboxylic acid derivatives
        • Level5 Carboxylic acid esters
          • Level6 Alpha,beta-unsaturated carboxylic esters
            • Level7 Enoate esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Carboxylic acid derivatives
• Intermediate Tree Nodes: Carboxylic acid esters - Alpha,beta-unsaturated carboxylic esters
• Direct Parent: Enoate esters
• Alternative Parents: Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Enoate ester - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as enoate esters. These are an alpha,beta-unsaturated carboxylic ester of general formula R1C(R2)=C(R3)C(=O)OR4 (R4= organyl compound) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position.
• External Descriptors: enoate ester

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light&Air Sensitive
• Refractive Index: 1.451-1.453
• Flash Point(°F): 222.8 °F
• Flash Point(°C): 101℃
• Boil Point(°C): 85°C/5mmHg
• Melt Point(°C): -12℃
• Molecular Weight: 130.139 g/mol
• XLogP3: 0.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 130.063 Da
• Monoisotopic Mass: 130.063 Da
• Topological Polar Surface Area: 46.500 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 117.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1