(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.
In Vitro
Treatment of IDH1-WT HeLa cells with (2R)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells. It has been used to examine the contribution of D-2-Hydroxyglutarate to the oxidative mitochondrial processes of IDH1-mutated cancer cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES
CCCCCCCCOC(=O)[C@@H](CCC(=O)O)O
PubChem CID
71749054
Molecular Weight
260.33
Advanced Data
Certificates (CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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