3-Picoline - ≥99.5%(GC) , CAS No.108-99-6

CAS: 108-99-6 Cat. No.: P109210 Molecular Weight: 93.13 Beilstein Registry Number: 1366 EC Number: 203-636-9
AVAILABLE TO ORDER
GRADE & PURITY ≥99.5%(GC)
Synonyms
BCP22897 | meta-Methylpyridine | F0001-0187 | DTXSID9021897 | SMR000568465 | 3-methyl pyridin | 3-Methyl pyridine | B083J4KF7F | EN300-19742 | HSDB 4254 | .BETA.-PICOLINE [MI] | 5HS | AI3-24110 | m-Picoline | InChI=1/C6H7N/c1-6-3-2-4-7-5-6/h2-5H,1H | NSC1
Storage
Room temperature
Shipped In
FedEx DG Service
Size
Status
Price
Qty
100ml
P109210-100ml
3
$125.90
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Why this grade

≥99.5%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 27 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
BCP22897 | meta-Methylpyridine | F0001-0187 | DTXSID9021897 | SMR000568465 | 3-methyl pyridin | 3-Methyl pyridine | B083J4KF7F | EN300-19742 | HSDB 4254 | .BETA.-PICOLINE [MI] | 5HS | AI3-24110 | m-Picoline | InChI=1/C6H7N/c1-6-3-2-4-7-5-6/h2-5H, 1H | NSC1
Specifications & Purity
≥99.5%(GC)
Storage
Room temperature
Shipped In
FedEx DG Service
Purity
≥99.5%(GC)
Names and Identifiers
Pubchem Sid488180630
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180630
Canonical SmilesCC1=CN=CC=C1
IUPAC Name3-methylpyridine
InChIKeyITQTTZVARXURQS-UHFFFAOYSA-N
INCHI1S/C6H7N/c1-6-3-2-4-7-5-6/h2-5H,1H3
Isomeric SMILES CC1=CN=CC=C1
WGK Germany 1
RTECS TJ5000000
UN Number 2313
Packing Group III
Molecular Weight 93.13
Beilstein 1366
Reaxy-Rn 1366
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1366&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPyridines and derivatives
SubclassMethylpyridines
Intermediate Tree Nodes Not available
Direct ParentMethylpyridines
Alternative Parents Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Methylpyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as methylpyridines. These are organic compounds containing a pyridine ring substituted at one or more positions by a methyl group.
External Descriptors methylpyridine
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXAS1 Tchem Thromboxane-A synthase (3355 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
G2617437Certificate of AnalysisJul 13, 2026 P109210
D2624304Certificate of AnalysisApr 20, 2026 P109210
D2609346Certificate of AnalysisApr 03, 2026 P109210
F2525479Certificate of AnalysisJun 17, 2025 P109210
K2413337Certificate of AnalysisOct 23, 2024 P109210
G2305758Certificate of AnalysisJun 13, 2023 P109210
G2305802Certificate of AnalysisJun 13, 2023 P109210
L2214274Certificate of AnalysisDec 05, 2022 P109210
Chemical and Physical Properties
SolubilitySoluble in water, alcohol, ether and most organic solvents.
Refractive Index 1.505-1.507
Flash Point(°F)98.6 °F
Flash Point(°C)38℃
Boil Point(°C)143-144°C
Melt Point(°C)-19°C
Molecular Weight93.130 g/mol
XLogP31.200
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass93.0578 Da
Monoisotopic Mass93.0578 Da
Topological Polar Surface Area12.900 Ų
Heavy Atom Count7
Formal Charge0
Complexity52.100
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Guolong Huo, Zhiyong Guo, Zhiguang Zhang, Xiaowei Zhou, Junhao Xin, Yuchen Zhang, Shuanyan Kang, Yanqin Yang, Nanwen Li.  (2023)  Effect of uniaxial stretching on gas separation performance of polyimide membranes.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2023.122046]
2. Huijie Zhao, Kaiyue Han, Yang Li.  (2023)  Strip-type flexible capacitive humidity sensor based on composite of polyimide and poly(glycidyl methacrylate): Fabrication, humidity sensitive performance and potential for detecting water content in liquids.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2023.132092]
3. Yani Zheng, Yin Dai, Junqiang Hong, Huizhu Fan, Qing Zhang, Wei Jiang, Wei Xu, Jianwen Fei, Junli Hong.  (2023)  Magnetic dummy template molecularly imprinted particles functionalized with dendritic nanoclusters for selective enrichment and determination of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in tobacco products.  RSC Advances,  13  (20): (13824-13833).  [PMID:37152563] [10.1039/D3RA00610G]
4. Tongxin Liu, Ruili Zhang, Guangcan Huang, Yabo Xie, Lin-Hua Xie, Jian-Rong Li.  (2023)  Mixed matrix membranes based on soluble perfluorinated metal-organic cage and polyimide for CO2/CH4 separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.124006]
5. Guozhen Liu, Renhao Li, Xi Chen, Long Cheng, Yu Liu, Gongping Liu, Wanqin Jin.  (2023)  Pyrolysis temperature-regulated gas transport and aging properties in 6FDA-DAM polyimide-derived carbon molecular sieve membranes.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.123459]
6. Maosheng Chen, Chenyu Ye, Chengqin Dai, Ruixiang Li, Ruijuan Qi, Chunhua Luo, Hui Peng, Hechun Lin.  (2023)  Self-assembly formation of CuI hybrid micron phosphors with tunable emission for multifunctional applications.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:36791481] [10.1016/j.jcis.2023.01.083]
7. Yonghong Wang, Lecheng Sheng, Xinru Zhang, Jinping Li, Rong Wang.  (2022)  Hybrid carbon molecular sieve membranes having ordered Fe3O4@ZIF-8-derived microporous structure for gas separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2022.121127]
8. Xi Yuchun, Yin Chuanqiang, Xu Lexiang, Xiong Wei, Xu Hang, Luo Jinpeng, Huang Shirong, Ma Lei, Zhou Lang, Li Xiaomin.  (2022)  Hexagonal boron nitride as the foaming agent to improve the flexibility of polyimide-derived graphite films with high thermal conductivity.  APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING,  128  (10): (1-11).  [PMID:] [10.1007/s00339-022-06044-4]
9. Ziqi Sun, Meiling Qi.  (2022)  High separation performance of carbon dioxide-based poly(ether-carbonate) copolymer for gas chromatographic analyses.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36166885] [10.1016/j.chroma.2022.463493]
10. Bingbing Luo, Kai Wu, Jiajun Yu, Siyu Wang, Yihan Wang, Chenyang Chu, Huiyan Zhang.  (2022)  Enhancement of renewable N-heterocycles production via catalytic co-pyrolysis of glycerol and cellulose over HZSM-5 under ammonia atmosphere.  JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS,      [PMID:] [10.1016/j.jaap.2022.105649]
11. Dong Fu, Xiaoru Gao, Jue Wang, Haijian Jiang, Mingming Zheng, Peng Li, Bo Huang, Kan Kan, Xiaochen Zhang.  (2022)  Micellization and thermodynamics study of ester functionalized picoline-based ionic liquid surfactants in water.  RSC Advances,  12  (23): (14477-14484).  [PMID:35702243] [10.1039/D2RA01706G]
12. Shan Xu, Xiaolong Ren, Ning Zhao, Lei Wu, Zhiguang Zhang, Yanfang Fan, Nanwen Li.  (2021)  Self-crosslinking of bromomethylated 6FDA-DAM polyimide for gas separations.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2021.119534]
13. Hao Ling, Qiufeng Mao, Sen Liu, Hongxia Gao, Juan Lv, Yu Mao, Zhiwu Liang.  (2021)  Simple and Shortcut Method for Evaluating and Guiding the Removal of Degradation Products, Improving Solvent Performance, and Reducing Regeneration Energy.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.0c05762]
14. Yuan Li, Yuyang Wei, Wenbin Zhang.  (2020)  Oxidation behavior of N-hydroxyphthalimide (NHPI) and its electrocatalytic ability toward benzyl alcohol: Proton acceptor effect.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.jelechem.2020.114251]
15. Min Fan, Dechan Lu, Ruiyun You, Cairou Chen, Yudong Lu, Yang Wu, Huiying Shen, Shangyuan Feng.  (2020)  Highly sensitive detection of tryptophan (Trp) in serum based on diazo-reaction coupling with Surface-Enhanced Raman Scattering and colorimetric assay.  ANALYTICA CHIMICA ACTA,      [PMID:32439054] [10.1016/j.aca.2020.04.039]
16. Xin Zhang, Ziguo Yuan, Qian Yao, Ying Zhang, Yao Fu.  (2019)  Catalytic fast pyrolysis of corn cob in ammonia with Ga/HZSM-5 catalyst for selective production of acetonitrile.  BIORESOURCE TECHNOLOGY,      [PMID:31319216] [10.1016/j.biortech.2019.121800]
17. Ziguo Yuan, Xin Zhang, Qian Yao, Ying Zhang, Yao Fu.  (2019)  Production of acetonitrile via catalytic fast pyrolysis of biomass derived polylactic acid under ammonia atmosphere.  JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS,      [PMID:] [10.1016/j.jaap.2019.04.017]
18. Min Hua, Min Qi, Xuhai Pan, Wendi Yu, Lu Zhang, Juncheng Jiang.  (2017)  Inherently safer design for synthesis of 3-methylpyridine-N-oxide.  PROCESS SAFETY PROGRESS,  37  (3): (355-361).  [PMID:] [10.1002/prs.11952]
19. Lujiang Xu, Qian Yao, Ying Zhang, Yao Fu.  (2016)  Producing pyridines via thermo-catalytic conversion and ammonization of glycerol over nano-sized HZSM-5.  RSC Advances,  (89): (86034-86042).  [PMID:] [10.1039/C6RA18603C]
20. L. Zhang, W.D. Yu, X.H. Pan, J.J. Fang, M. Hua, F.M. Chen, J.C. Jiang.  (2015)  Thermal hazard assessment for synthesis of 3-methylpyridine-N-oxide.  JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES,      [PMID:] [10.1016/j.jlp.2015.03.022]
21. Erkang Li, Yujie Zhen, Lu Chen, Xuqiang Li, Lei Li, Wenxue Lu, Tao Li, Qingsong Li, Yingmin Yu.  (2024)  Thermodynamic and quantum chemical investigation of MIBK as a liquid phase extraction solvent for separating pyridine compounds from water.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2024.124876]
22. Weilin Feng, Fupeng Li, Jiaqi Li, Zhiyi Li, Lu Xu, Hukang Guo, Nanwen Li, Xinzhong Cao, Chuanjie Fang, Baoku Zhu, Liping Zhu.  (2025)  Asymmetrical polyimide membranes with programmable polymer chain architectures for liquid hydrocarbon fractionation.  Science Advances,  11  (37):   [PMID:40939002] [10.1126/sciadv.ady3674]
23. Haifei Jiang, Yu Chen, Shuqing Song, Zheyuan Guo, Zhengqing Zhang, Chenyang Zheng, Guangwei He, Hongjian Wang, Hong Wu, Tong Huang, Yanxiong Ren, Xin Liu, Junfeng Zhang, Yan Yin, Zhongyi Jiang, Michael D. Guiver.  (2022)  Confined facilitated transport within covalent organic frameworks for propylene/propane membrane separation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.135657]
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