4,4'-Dithiodimorpholine - ≥98%(HPLC) , CAS No.103-34-4

CAS: 103-34-4 Cat. No.: D155981 Molecular Weight: 236.35 EC Number: 203-103-0

GRADE & PURITY ≥98%(HPLC)

Synonyms

NSC 65239 | Sulfasan R | 1,2-dimorpholinodisulfane | 4-(4-Morpholinyldisulfanyl)morpholine # | 4,4'-Dithiobismorpholine | Bis(4-morpholinyl)disulfide | N,N'-DimorpholineDisulfide | Usaf ek-t-6645 | 4,4/'-Dithiodimorpholine | 4,4'-disulfanediyldimorpholine

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

NSC 65239 | Sulfasan R | 1, 2-dimorpholinodisulfane | 4-(4-Morpholinyldisulfanyl)morpholine # | 4, 4'-Dithiobismorpholine | Bis(4-morpholinyl)disulfide | N, N'-DimorpholineDisulfide | Usaf ek-t-6645 | 4, 4/'-Dithiodimorpholine | 4, 4'-disulfanediyldimorpholine

Specifications & Purity

≥98%(HPLC)

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504751420
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504751420
• Canonical Smiles: C1COCCN1SSN2CCOCC2
• IUPAC Name: 4-(morpholin-4-yldisulfanyl)morpholine
• InChIKey: HLBZWYXLQJQBKU-UHFFFAOYSA-N
• INCHI: 1S/C8H16N2O2S2/c1-5-11-6-2-9(1)13-14-10-3-7-12-8-4-10/h1-8H2
• Isomeric SMILES: C1COCCN1SSN2CCOCC2
• RTECS: QE3325000
• Molecular Weight: 236.35
• Reaxy-Rn: 126214
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=126214&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Oxazinanes
      • Subclass Morpholines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Oxazinanes
• Subclass: Morpholines
• Intermediate Tree Nodes: Not available
• Direct Parent: Morpholines
• Alternative Parents: Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Morpholine - Oxacycle - Azacycle - Ether - Dialkyl ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

MCF7 (126967 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

T47D (39041 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDA-MB-231 (73002 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Heat Sensitive
• Melt Point(°C): 125°C
• Molecular Weight: 236.400 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 236.065 Da
• Monoisotopic Mass: 236.065 Da
• Topological Polar Surface Area: 75.500 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 143.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Haotian Zhang, Rihui Liang, Qianshu Wang, Wenbo Luan, Jun Ye, Teng Qiu, Xinlin Tuo.  (2023)  The Post-Curing of Waterborne Polyurethane–Acrylate Composite Latex with the Dynamic Disulfide-Bearing Crosslinking Agent.  MOLECULES,  28  (24): (8122).  [PMID:38138610] [10.3390/molecules28248122]

2. Yan Zhixiang, Liu Chenyao, Zheng Shuo, Tan Zhiyong.  (2025)  A nonpolar group disulfide bonds driven polyurethane with enhanced dielectric properties.  JOURNAL OF POLYMER RESEARCH,  32  (2): (1-11).  [PMID:] [10.1007/s10965-025-04258-7]

3. Ming Chen, Mengqing Ren, Jiaming Chen, Yajun Lu, Qingsong Shi, Lili Wu.  (2024)  Self-healing waterborne polyurethane elastomers based on synergistic hydrogen, disulfide and borate bonding for composite conductors.  JOURNAL OF POLYMER SCIENCE,  62  (15): (3381-3398).  [PMID:] [10.1002/pol.20240095]