4-Hydroxy Propofol 4-O-β-D-Glucuronide - ≥98% , CAS No.115005-78-2

CAS: 115005-78-2 Cat. No.: H352665 Formula: C₁₈H₂₆O₈ Molecular Weight: 370.39 PubChem CID: 92131911

GRADE & PURITY ≥98%

Synonyms

4-Hydroxy-3,5-bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

4-Hydroxy Propofol 1-O-β-D-Glucuronide is a metabolite of Propofol modified at position 4 with an O-linked β-glycosidic bond. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.

Specifications

Synonyms

4-Hydroxy-3,5-bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid

Specifications & Purity

≥98%

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

Pubchem Sid

504772731

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504772731

Canonical Smiles

CC(C)C1=CC(=CC(=C1O)C(C)C)OC2C(C(C(C(O2)C(=O)O)O)O)O

IUPAC Name

(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-hydroxy-3,5-di(propan-2-yl)phenoxy]oxane-2-carboxylic acid

InChIKey

UXCRGVWMLWGVRH-RNGZQALNSA-N

INCHI

1S/C18H26O8/c1-7(2)10-5-9(6-11(8(3)4)12(10)19)25-18-15(22)13(20)14(21)16(26-18)17(23)24/h5-8,13-16,18-22H,1-4H3,(H,23,24)/t13-,14-,15+,16-,18+/m0/s1

Isomeric SMILES

CC(C)C1=CC(=CC(=C1O)C(C)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O

PubChem CID

92131911

Molecular Weight

370.39

Chemical and Physical Properties

• Solubility: Soluble in Methanol
• Sensitivity: Hygroscopic
• Melt Point(°C): 116-118° C