4-Nitroguaiacol - ≥98% , CAS No.3251-56-7

CAS: 3251-56-7 Cat. No.: N159820 Formula: C7H7NO4 Molecular Weight: 169.14 EC Number: 221-839-0
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
3-Nitro-6-hydroxyanisole | AM808244 | NSC-11688 | Guaiacol, 4-nitro- | 2-Methoxy-4-nitrophenol | 2-methoxy-4-nitro-phenol | 4-nitro-2-methoxyphenol | 2-(Methyloxy)-4-nitrophenol | Bis Amide | 41ITO2N6UT | o-Methoxy-p-nitrophenol | SY004543 | BCP17330 | FT
Storage
Room temperature
Shipped In
Normal
★
Size
Germany (EU)
USA*
Price
Qty
5g
N159820-5g
—
6 In stock
€8.59
10g
N159820-10g
—
4 In stock
€15.53
25g
N159820-25g
—
4 In stock
€32.02
100g
N159820-100g
—
In stock ≥10
€115.32
500g
N159820-500g
Made to order · 8–12 wks
€570.89
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
3-Nitro-6-hydroxyanisole | AM808244 | NSC-11688 | Guaiacol, 4-nitro- | 2-Methoxy-4-nitrophenol | 2-methoxy-4-nitro-phenol | 4-nitro-2-methoxyphenol | 2-(Methyloxy)-4-nitrophenol | Bis Amide | 41ITO2N6UT | o-Methoxy-p-nitrophenol | SY004543 | BCP17330 | FT
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/488185321
Canonical Smiles
COC1=C(C=CC(=C1)[N+](=O)[O-])O
IUPAC Name
2-methoxy-4-nitrophenol
InChIKey
IZLVFLOBTPURLP-UHFFFAOYSA-N
INCHI
1S/C7H7NO4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3
Isomeric SMILES
COC1=C(C=CC(=C1)[N+](=O)[O-])O
RTECS
SL7800000
Molecular Weight
169.14
Reaxy-Rn
1868796
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1868796&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassNitrobenzenes
Intermediate Tree Nodes Not available
Direct ParentNitrophenyl ethers
Alternative Parents Methoxyphenols  Nitrophenols  Methoxyanilines  Phenoxy compounds  Nitroaromatic compounds  Methoxybenzenes  Anisoles  1-hydroxy-2-unsubstituted benzenoids  Alkyl aryl ethers  Organic oxoazanium compounds  Propargyl-type 1,3-dipolar organic compounds  Organonitrogen compounds  Organic zwitterions  Organic oxides  Hydrocarbon derivatives  Organopnictogen compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Nitrophenyl ether - Methoxyphenol - Nitrophenol - Methoxyaniline - Phenoxy compound - Nitroaromatic compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - Phenol - C-nitro compound - Organic nitro compound - Ether - Organic oxoazanium - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organonitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organic nitrogen compound - Organic zwitterion - Organopnictogen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as nitrophenyl ethers. These are aromatic compounds containing a nitrobenzene moiety that carries an ether group on the benzene ring.
External Descriptors C-nitro compound - phenols
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot NumberCertificate TypeDateItem
D1903103Certificate of AnalysisOct 09, 2026 N159820
L2209916Certificate of AnalysisSep 01, 2026 N159820
L2209917Certificate of AnalysisSep 01, 2026 N159820
L2209922Certificate of AnalysisSep 01, 2026 N159820
L2209947Certificate of AnalysisSep 01, 2026 N159820
L2209965Certificate of AnalysisSep 01, 2026 N159820
L2209978Certificate of AnalysisSep 01, 2026 N159820
C2209210Certificate of AnalysisDec 10, 2025 N159820
H2525655Certificate of AnalysisAug 26, 2025 N159820
D2323498Certificate of AnalysisNov 25, 2022 N159820
L2209976Certificate of AnalysisNov 25, 2022 N159820
L2209979Certificate of AnalysisNov 25, 2022 N159820
Chemical and Physical Properties
SolubilitySoluble in Methanol
Melt Point(°C)102-104°C
Molecular Weight169.130 g/mol
XLogP30.700
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass169.038 Da
Monoisotopic Mass169.038 Da
Topological Polar Surface Area75.300 Ų
Heavy Atom Count12
Formal Charge0
Complexity167.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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