Advantame - ≥98% , CAS No.714229-20-6

CAS: 714229-20-6 Cat. No.: A352729 Molecular Weight: 476.52 PubChem CID: 56843846
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
ADVANTAME [USP-RS] | N-(N-(3-(3-HYDROXY-4-METHOXYPHENYL) PROPYL)-L-.ALPHA.-ASPARTYL)-L-PHENYLALANINE-1-METHYL ESTER, MONOHYDRATE | SCHEMBL2156362 | L-Phenylalanine, N-(3-(3-hydroxy-4-methoxyphenyl)propyl)-l-alpha-aspartyl-, 2-methyl ester, monohydrate | 3
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25mg
A352729-25mg
1
$25.90
100mg
A352729-100mg
1
$69.90
250mg
A352729-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
1g
A352729-1g
3
$347.90
5g
A352729-5g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,119.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Advantame is a non-caloric artificial sweetener, analogue of aspartame, commonly used as a food additive.

Specifications

Synonyms
ADVANTAME [USP-RS] | N-(N-(3-(3-HYDROXY-4-METHOXYPHENYL) PROPYL)-L-.ALPHA.-ASPARTYL)-L-PHENYLALANINE-1-METHYL ESTER, MONOHYDRATE | SCHEMBL2156362 | L-Phenylalanine, N-(3-(3-hydroxy-4-methoxyphenyl)propyl)-l-alpha-aspartyl-, 2-methyl ester, monohydrate | 3
Specifications & Purity
≥98%
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Canonical SmilesCOC1=C(C=C(C=C1)CCCNC(CC(=O)O)C(=O)NC(CC2=CC=CC=C2)C(=O)OC)O.O
IUPAC Name(3S)-3-[3-(3-hydroxy-4-methoxyphenyl)propylamino]-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid;hydrate
InChIKeyNQQIEOGMDRFTDZ-HLRBRJAUSA-N
INCHI1S/C24H30N2O7.H2O/c1-32-21-11-10-17(14-20(21)27)9-6-12-25-18(15-22(28)29)23(30)26-19(24(31)33-2)13-16-7-4-3-5-8-16;/h3-5,7-8,10-11,14,18-19,25,27H,6,9,12-13,15H2,1-2H3,(H,26,30)(H,28,29);1H2/t18-,19-;/m0./s1
Isomeric SMILES COC1=C(C=C(C=C1)CCCN[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OC)O.O
PubChem CID 56843846
Molecular Weight 476.52

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
D2501135Certificate of AnalysisMar 25, 2025 A352729
D2501136Certificate of AnalysisMar 25, 2025 A352729
D2501137Certificate of AnalysisMar 25, 2025 A352729
D2525028Certificate of AnalysisMar 25, 2025 A352729
K2407263Certificate of AnalysisOct 25, 2024 A352729
K2407264Certificate of AnalysisOct 25, 2024 A352729
K2407265Certificate of AnalysisOct 25, 2024 A352729
K2407266Certificate of AnalysisOct 25, 2024 A352729
Chemical and Physical Properties
SensitivityAir sensitive;Moisture sensitive.
Melt Point(°C)>64° C (dec.)
Citations of This Product
References
1. Cai Shuangfeng, Xie Ningning, Zheng Ling, Li Quan, Zhang Siyu, Huang Qinghua, Luo Wei, Wu Mei, Wang Yidan, Du Yilun, Deng Shao-ping, Cai Lei.  (2024)  Sweet taste receptors play roles in artificial sweetener-induced enhanced urine output in mice.  npj Science of Food,  (1): (1-7).  [PMID:38182603] [10.1038/s41538-023-00236-9]
Solution Calculators
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