Aldometanib - ≥99% , CAS No.A659456

CAS: A659456 Cat. No.: A659456 Molecular Weight: 593.45

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis

Appearance:Solid

In Vitro:Aldometanib (0-1000 nM; 2 h) activates AMPK by preventing aldolase from binding to FBP to engender a pseudo-starvation signal. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisC

In Vivo:Aldometanib (oral; 0-10 mpk) reduces blood glucose in lean mice. Aldometanib (oral; 2-10 mpk; twice daily; for a week) reduces blood glucose and alleviates fatty liver in obese hyperglycaemic mice. Aldometanib alleviates fatty liver and nonalcoh

Biological Activity:Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis

Specifications

Specifications & Purity

≥99%

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CCCCCCCCCCCCCCCCN1C=C[N+](CC2=C(Cl)C=CC=C2Cl)=C1C.[I-]
• Molecular Weight: 593.45

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (168.51 mM; ultrasonic and warming and heat to 60°C)