AMT hydrochloride - ≥98% , CAS No.21463-31-0

CAS: 21463-31-0 Cat. No.: A287779 Molecular Weight: 166.67
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
SMR000326965 | EU-0100085 | CCG-221389 | J-014084 | 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride | NCGC00260770-01 | MLS000862202 | WAA46331 | AMTHYDROCHLORIDE | AMT hydrochloride | AMT (hydrochloride) | 6-methyl-5,6-dihydro-4H-1,3-thiazin-2
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
A287779-1mg
2
$57.90
5mg
A287779-5mg
2
$199.90
10mg
A287779-10mg
2
$339.90
25mg
A287779-25mg
2
$679.90
50mg
A287779-50mg
1
$1,085.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
SMR000326965 | EU-0100085 | CCG-221389 | J-014084 | 2-Amino-5, 6-dihydro-6-methyl-4H-1, 3-thiazine hydrochloride | NCGC00260770-01 | MLS000862202 | WAA46331 | AMTHYDROCHLORIDE | AMT hydrochloride | AMT (hydrochloride) | 6-methyl-5, 6-dihydro-4H-1, 3-thiazin-2
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Potent, selective and reversible inhibitor of iNOS (IC50= 3.6 nM; approximately 30 and 40 times selective over nNOS and eNOS respectively).
Storage
Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
Canonical SmilesCC1CCN=C(S1)N.Cl
IUPAC Name6-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine;hydrochloride
InChIKeyHVJCRMIQAMEJNM-UHFFFAOYSA-N
INCHI1S/C5H10N2S.ClH/c1-4-2-3-7-5(6)8-4;/h4H,2-3H2,1H3,(H2,6,7);1H
Isomeric SMILES CC1CCN=C(S1)N.Cl
Molecular Weight 166.67
Reaxy-Rn 5390939
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5390939&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassThiazines
Subclass1,3-thiazines
Intermediate Tree Nodes Not available
Direct Parent1,3-thiazines
Alternative Parents Isothioureas  Propargyl-type 1,3-dipolar organic compounds  Carboximidamides  Azacyclic compounds  Organopnictogen compounds  Hydrochlorides  Hydrocarbon derivatives  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents Meta-thiazine - Isothiourea - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Aliphatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 1,3-thiazines. These are organic compounds containing 1,3-thiazine, a six-member ring with a nitrogen and a sulfur atoms in ring positions 1 and 3 respectively, as well as two double bonds.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
F2404107Certificate of AnalysisMar 04, 2024 A287779
F2404108Certificate of AnalysisMar 04, 2024 A287779
F2404109Certificate of AnalysisMar 04, 2024 A287779
F2404110Certificate of AnalysisMar 04, 2024 A287779
F2404111Certificate of AnalysisMar 04, 2024 A287779
F2404112Certificate of AnalysisMar 04, 2024 A287779
F2404113Certificate of AnalysisMar 04, 2024 A287779
F2404114Certificate of AnalysisMar 04, 2024 A287779
F2404115Certificate of AnalysisMar 04, 2024 A287779
F2404116Certificate of AnalysisMar 04, 2024 A287779
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: None, Max Conc. mM: 10
Molecular Weight166.670 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass166.033 Da
Monoisotopic Mass166.033 Da
Topological Polar Surface Area63.700 Ų
Heavy Atom Count9
Formal Charge0
Complexity111.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Documents & Articles
Citations of This Product
References
1. Chaoli Tang, Dachao Fu, Rujing Wang, Xiaoyu Zhang, Liman Wei, Mingjun Li, Chengpan Li, Qiao Cao, Xiangyu Chen.  (2024)  An Electrochemical Microfluidic System for On-site Continuous Monitoring of Soil Phosphate.  IEEE SENSORS JOURNAL,      [PMID:] [10.1109/JSEN.2023.3348807]
Solution Calculators
Reviews

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