Anagrelide HCl - 10mM in DMSO , Phosphodiesterase 3 inhibitor, CAS No.58579-51-4, Phosphodiesterase 3 inhibitor

CAS: 58579-51-4 Cat. No.: A408166 Molecular Weight: 292.55 EC Number: 680-360-9

GRADE & PURITY 10mM in DMSO

Synonyms

BL-4162A | 6,7-dichloroimidazo[2,1-b]quinazolin-2(1H,3H,5H)-one hydrochloride

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Anagrelide HCl Anagrelide (BL-4162A) is a drug used for the treatment of essential thrombocytosis.
In vitro

Anagrelide is an oral imidazoquinazoline agent with an anti-cyclic AMP phosphodiesterase activity and inhibits platelet aggregation in both humans and animals. Anagrelide works by inhibiting the maturation of platelets from megakaryocytes.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

BL-4162A | 6, 7-dichloroimidazo[2, 1-b]quinazolin-2(1H, 3H, 5H)-one hydrochloride

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Anagrelide (BL-4162A) is a drug used for the treatment of essential thrombocytosis.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Phosphodiesterase 3 inhibitor

Names and Identifiers

• Isomeric SMILES: C1C2=C(C=CC(=C2Cl)Cl)N=C3N1CC(=O)N3.Cl
• WGK Germany: 3
• Molecular Weight: 292.55
• Reaxy-Rn: 4614131
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4614131&ln=

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro Water: 100 mg/mL DMSO: Insoluble; Ethanol: Insoluble