Antipyrine - 10mM in DMSO , Cyclooxygenase-1 inhibitor, CAS No.60-80-0, Cyclooxygenase-1 inhibitor

CAS: 60-80-0 Cat. No.: A408977 Formula: C₁₁H₁₂N₂O Molecular Weight: 188.23 Beilstein Registry Number: 157775 EC Number: 200-486-6

GRADE & PURITY 10mM in DMSO

Synonyms

Phenazone | 1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Antipyrine Antipyrine (Phenazone) is an analgesic and antipyretic agent; selective COX-3 inhibitor.
In vitro

Antipyrine is an analgesic and antipyretic.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

Phenazone | 1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Antipyrine (Phenazone) is an analgesic and antipyretic agent; selective COX-3 inhibitor.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Cyclooxygenase-1 inhibitor

Product Properties

ALogP

0.4

Names and Identifiers

Isomeric SMILES

CC1=CC(=O)N(N1C)C2=CC=CC=C2

WGK Germany

1

RTECS

CD2450000

Molecular Weight

188.23

Beilstein

157775

Reaxy-Rn

157775

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=157775&ln=

Associated Targets(Human)

NAPRT Tchem Nicotinate phosphoribosyltransferase (2 Activities)

Discover Target: NAPRT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Refractive Index: 1.5697
• Boil Point(°C): 319°C
• Melt Point(°C): 114°C

Frequently Asked Questions

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 60-80-0, the molecular formula is C11H12N2O, and the molecular weight is 188.23 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.