Bim-IN-1 - ≥99% , CAS No.B658688

CAS: B658688 Cat. No.: B658688 Formula: C₁₉H₂₀Cl₂FNO₂S Molecular Weight: 416.34

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity.

Appearance:Solid

IC50& Target:Bim

In Vitro:Bim-IN-1 (compound 63, mouse embryonic fibroblasts; 0, 25, 50 μM; 72 hours) demonstrates strong reduction of Bim expression levels at a low micromolar level with low toxicity. MCE has not independently confirmed the accuracy of these methods. They ar

Biological Activity:Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity.

Specifications

Specifications & Purity

≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

Canonical Smiles

FC1=CC(C2N(S(=O)(CC3=CC=C(Cl)C=C3Cl)=O)CCCCC2)=CC=C1

Molecular Weight

416.34

Chemical and Physical Properties

• Solubility: DMSO : 200 mg/mL (480.38 mM; Need ultrasonic)