Bis(cyclohexanone)oxalyldihydrazone - Reagent grade , CAS No.370-81-0

CAS: 370-81-0 Cat. No.: B110707 Molecular Weight: 278.35 Beilstein Registry Number: 2388004 EC Number: 206-729-2
AVAILABLE TO ORDER
GRADE & PURITY Reagent Grade ? General reagent-grade purity suitable for most laboratory work. Use as a dependable default when no specific higher grade is required.
Synonyms
OXALIC ACID, BIS(CYCLOHEXYLIDENEHYDRAZIDE) | UNII-5N16U7E0AO | Ethanedioic acid, bis(cyclohexylidene hydrazide) | Cupferazone | DSRJIHMZAQEUJV-UHFFFAOYSA-N | AS-75478 | InChI=1/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
B110707-5g
5
$9.90
25g
B110707-25g
≥10
$13.90
100g
B110707-100g
2
$39.90
Enter a quantity for the sizes you want to add.
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Why this grade

Reagent grade Reagent Grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

A stain used in the quantitative spectroscopic determination of copper.

Specifications

Synonyms
OXALIC ACID, BIS(CYCLOHEXYLIDENEHYDRAZIDE) | UNII-5N16U7E0AO | Ethanedioic acid, bis(cyclohexylidene hydrazide) | Cupferazone | DSRJIHMZAQEUJV-UHFFFAOYSA-N | AS-75478 | InChI=1/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2, (
Specifications & Purity
Reagent grade
Biochemical and Physiological Mechanisms
Bis(cyclohexanone)oxaldihydrazone used in the quantitative spectroscopic determination of copper as well as for the experimental study of mitochondrial metabolism.
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Reagent Grade
Names and Identifiers
Pubchem Sid488181018
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181018
Canonical SmilesC1CCC(=NNC(=O)C(=O)NN=C2CCCCC2)CC1
IUPAC NameN,N'-bis(cyclohexylideneamino)oxamide
InChIKeyDSRJIHMZAQEUJV-UHFFFAOYSA-N
INCHI1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
Isomeric SMILES C1CCC(=NNC(=O)C(=O)NN=C2CCCCC2)CC1
WGK Germany 3
RTECS RO2520000
Molecular Weight 278.35
Beilstein 2388004
Reaxy-Rn 2388004
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2388004&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives
Direct ParentAlpha amino acids and derivatives
Alternative Parents Semioxamazones  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Alpha-amino acid or derivatives - Semioxamazone - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
External Descriptors a small molecule
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

22 results found

Lot NumberCertificate TypeDateItem
D2623166Certificate of AnalysisMay 07, 2026 B110707
D2623165Certificate of AnalysisMay 07, 2026 B110707
C2604114Certificate of AnalysisMar 20, 2026 B110707
L2109420Certificate of AnalysisSep 09, 2025 B110707
B2525502Certificate of AnalysisFeb 27, 2025 B110707
B2520322Certificate of AnalysisFeb 24, 2025 B110707
B2520327Certificate of AnalysisFeb 24, 2025 B110707
L2404313Certificate of AnalysisDec 06, 2024 B110707
L2404312Certificate of AnalysisDec 06, 2024 B110707
I2410279Certificate of AnalysisSep 12, 2024 B110707
B2418106Certificate of AnalysisFeb 28, 2024 B110707
H2405030Certificate of AnalysisFeb 28, 2024 B110707
G2412066Certificate of AnalysisDec 18, 2023 B110707
L2308109Certificate of AnalysisDec 18, 2023 B110707
H2322050Certificate of AnalysisAug 29, 2023 B110707
B2303067Certificate of AnalysisFeb 07, 2023 B110707
B2303065Certificate of AnalysisFeb 07, 2023 B110707
B2303061Certificate of AnalysisFeb 07, 2023 B110707
B2303060Certificate of AnalysisFeb 07, 2023 B110707
B2302984Certificate of AnalysisFeb 07, 2023 B110707
L2109421Certificate of AnalysisDec 14, 2021 B110707
L2320022Certificate of AnalysisDec 14, 2021 B110707

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Chemical and Physical Properties
SolubilityInsoluble in water.
SensitivityMoisture Sensitive
Melt Point(°C)213°C
Molecular Weight278.350 g/mol
XLogP31.600
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass278.174 Da
Monoisotopic Mass278.174 Da
Topological Polar Surface Area82.900 Ų
Heavy Atom Count20
Formal Charge0
Complexity373.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Ziyang He, Qiang Huang, Liucheng Mao, Hongye Huang, Meiying Liu, Junyu Chen, Fengjie Deng, Naigen Zhou, Xiaoyong Zhang, Yen Wei.  (2020)  Direct surface modification of nanodiamonds with ionic copolymers for fast adsorptive removal of copper ions with high efficiency.  Colloid and Interface Science Communications,      [PMID:] [10.1016/j.colcom.2020.100278]
2. Yan Liu, Hongye Huang, Defu Gan, Linru Guo, Meiying Liu, Junyu Chen, Fengjie Deng, Naigen Zhou, Xiaoyong Zhang, Yen Wei.  (2018)  A facile strategy for preparation of magnetic graphene oxide composites and their potential for environmental adsorption.  CERAMICS INTERNATIONAL,      [PMID:] [10.1016/j.ceramint.2018.07.081]
3. Zhanying Li, Lin Shao, Zehai Ruan, Wenbin Hu, Lingbin Lu, Yongjun Chen.  (2018)  Converting untreated waste office paper and chitosan into aerogel adsorbent for the removal of heavy metal ions.  CARBOHYDRATE POLYMERS,      [PMID:29773376] [10.1016/j.carbpol.2018.04.003]
4. Qiang Huang, Jiao Zhao, Meiying Liu, Junyu Chen, Xiaoli Zhu, Ting Wu, Jianwen Tian, Yuanqing Wen, Xiaoyong Zhang, Yen Wei.  (2017)  Preparation of polyethylene polyamine@tannic acid encapsulated MgAl-layered double hydroxide for the efficient removal of copper (II) ions from aqueous solution.  Journal of the Taiwan Institute of Chemical Engineers,      [PMID:] [10.1016/j.jtice.2017.10.019]
5. Qiang Huang, Meiying Liu, Jiao Zhao, Junyu Chen, Guangjian Zeng, Hongye Huang, Jianwen Tian, Yuanqing Wen, Xiaoyong Zhang, Yen Wei.  (2017)  Facile preparation of polyethylenimine-tannins coated SiO2 hybrid materials for Cu2+ removal.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2017.08.233]
6. Huang Qiang, Liu Meiying, Guo Ren, Mao Liucheng, Wan Qing, Zeng Guangjian, Huang Hongye, Deng Fengjie, Zhang Xiaoyong, Wei Yen.  (2016)  Facile synthesis and characterization of poly(levodopa)-modified silica nanocomposites via self-polymerization of levodopa and their adsorption behavior toward Cu2+.  JOURNAL OF MATERIALS SCIENCE,  51  (21): (9625-9637).  [PMID:] [10.1007/s10853-016-0178-z]
7. Ang Li, Runjun Lin, Chong Lin, Bianyang He, Tingting Zheng, Lingbin Lu, Yang Cao.  (2016)  An environment-friendly and multi-functional absorbent from chitosan for organic pollutants and heavy metal ion.  CARBOHYDRATE POLYMERS,      [PMID:27185140] [10.1016/j.carbpol.2016.04.070]
8. Xiaoliang Zhang, Xiaohong Chen, Xiaofang Shi, Xiaochun Li, Hua-Zhong Yu.  (2024)  Microscale quantitation of heavy metals by back-scattering interferometry in conjunction with photothermal effect using a single laser beam.  TALANTA,      [PMID:39721133] [10.1016/j.talanta.2024.127390]
9. Meiting Li, Zhuoyin Liu, Dan Peng, Yadong Liu, Lili Cheng, Baizhu Chen, Jie Liu.  (2025)  Multifunctional porous organic polymer-based hybrid nanoparticles for sonodynamically enhanced cuproptosis and synergistic tumor therapy.  Acta Biomaterialia,      [PMID:39993518] [10.1016/j.actbio.2025.02.045]
10. Fang Li, Nuotong Shen, Qingcheng Li, Chen Yang, Limin Zhang, Mingjin Wang.  (2024)  Multiplexed microfluidic chip based flow injection analysis system for simultaneous determination of Fe(III), Mn(II) and Cu(II).  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.112346]
11. Yaojun Ju, Yichen Yan, Xinhui Wang, Shan Li, Jialei Wang, Zixiao Wang, Yuling Dong, Junping Wang.  (2025)  Acer truncatum Bunge seeds oil ameliorated cuprizone induced cognitive decline and brain white matter impairment by improving sphingomyelin metabolism and neuroinflammation via activation of TREM2 signaling pathway.  Food & Function,      [PMID:41284332] [10.1039/D5FO03220B]
12. Fei Chen, Sisi Wu, Jian Kuang, Sijia Xiang, Shenghu Wang, Siming Yuan, Kaiming Cao, Lu Yu, Wenming Yang, Liqin Tang, Yangzhong Liu.  (2026)  Rosmarinic Acid Is an hCtr1 Inhibitor that Interferes with Copper Transport Activity.  INORGANIC CHEMISTRY,      [PMID:41494012] [10.1021/acs.inorgchem.5c04906]
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