BIS-TRIS(Bis-Tris) - Ultra pure, ≥99%(T), suitable where a calcium phosphate-DNA complex formation is desirable , CAS No.6976-37-0

CAS: 6976-37-0 Cat. No.: B755530 Formula: C₈H₁₉NO₅ Molecular Weight: 209.24 Beilstein Registry Number: 2205275 EC Number: 686-880-2

GRADE & PURITY Ultra pure, ≥99%(T), suitable where a calcium phosphate-DNA complex formation is desirable

Storage

Room temperature

Shipped In

Normal

Overview

A zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature. Useful in the pH 5.8-7.3 range. Has a pK_a of 6.50 at 25°C. Suitable for fractionation of hemoglobin.

Absorbance (100 mM, H₂O, 280 nm):≤0.04.

An inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature (absorbance: <0.04 at 280 nm, 100 mM, H₂O). Suitable for fractionation of hemoglobin. Has a pK_a of 6.5 at 25°C.

Specifications

Specifications & Purity

Ultra pure, ≥99%(T), suitable where a calcium phosphate-DNA complex formation is desirable

Storage

Room temperature

Shipped In

Normal

Grade

Ultra pure

Purity

≥99%(T)

Names and Identifiers

Canonical Smiles

C(CO)N(CCO)C(CO)(CO)CO

IUPAC Name

2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol

InChIKey

OWMVSZAMULFTJU-UHFFFAOYSA-N

INCHI

1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2

Isomeric SMILES

C(CO)N(CCO)C(CO)(CO)CO

WGK Germany

3

Molecular Weight

209.24

Beilstein

2205275

Reaxy-Rn

2205275

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2205275&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Alkanolamines
          • Level6 1,2-aminoalcohols

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Alkanolamines
• Direct Parent: 1,2-aminoalcohols
• Alternative Parents: Trialkylamines Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Tertiary aliphatic amine - Tertiary amine - 1,2-aminoalcohol - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
• External Descriptors: pentol

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: water: soluble
• Melt Point(°C): 103-104°C
• Molecular Weight: 209.240 g/mol
• XLogP3: -3.300
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 209.126 Da
• Monoisotopic Mass: 209.126 Da
• Topological Polar Surface Area: 104.000 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 125.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1