Blarcamesine(AVex-73) - Moligand™, ≥98% , Agonist of sigma non-opioid intracellular receptor 1, CAS No.195615-83-9, Agonist of sigma non-opioid intracellular receptor 1

CAS: 195615-83-9 Cat. No.: B608105 Formula: C19H23NO Molecular Weight: 281.39
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
1-(2,2-Diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine | AVex-73 | AE-37
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Germany (EU)
USA*
Price
Qty
1mg
B608105-1mg
Made to order · 8–12 wks
€17.27
5mg
B608105-5mg
Made to order · 8–12 wks
€34.62
25mg
B608105-25mg
Made to order · 8–12 wks
€91.89
100mg
B608105-100mg
Made to order · 8–12 wks
€257.63
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.

Specifications

Synonyms
1-(2,2-Diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine | AVex-73 | AE-37
Specifications & Purity
Moligand™, ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of sigma non-opioid intracellular receptor 1
Purity
≥98%
Names and Identifiers
Canonical SmilesCN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3
IUPAC Name1-(2,2-diphenyloxolan-3-yl)-N,N-dimethylmethanamine
InChIKeyBOTHKNZTGGXFEQ-UHFFFAOYSA-N
INCHI1S/C19H23NO/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,18H,13-15H2,1-2H3
Isomeric SMILES CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3
Alternate CAS 195615-83-9
MeSH Entry Terms ANAVEX2-73;blarcamesine;tetrahydro-N, N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride
Molecular Weight 281.39

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassDiphenylmethanes
Intermediate Tree Nodes Not available
Direct ParentDiphenylmethanes
Alternative Parents Aralkylamines  Oxolanes  Trialkylamines  Oxacyclic compounds  Dialkyl ethers  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Diphenylmethane - Aralkylamine - Oxolane - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Organoheterocyclic compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Amine - Organic nitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Molecular Weight281.400 g/mol
XLogP33.500
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass281.178 Da
Monoisotopic Mass281.178 Da
Topological Polar Surface Area12.500 Ų
Heavy Atom Count21
Formal Charge0
Complexity298.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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