Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+ -dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis .
| Isomeric SMILES | C[C@@H]1CC[C@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)C3=CC=CN3)C)C)O[C@@H]1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC |
|---|---|
| Molecular Weight | 523.62 |
| Reaxy-Rn | 1096801 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1096801&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Geng Xiao-Ling, Li Jing-Yu, Xu Huan-Yu, Wu Jiang-Ping, Tao De-Liang, Chen Jin-Ming, Fan Ying-Ying, Yang Xin, Song Jun-Ke, Zhao Guang-Hui. (2025) Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite. Parasites & Vectors, 18 (1): (1-15). [PMID:40731026] [10.1186/s13071-025-06966-x] |
| 2. Wang Zengbao, Li Taifeng, Jiang Yingying, Wang Xue, Li Hongmei, Zhao Xiaomin, Zhang Xiao, Zhao Ningning. (2025) EtSERPIN1 binding with chicken ANXA2 is essential for Eimeria tenella attachment and invasion process. VETERINARY RESEARCH, 56 (1): (1-13). [PMID:40640951] [10.1186/s13567-025-01532-w] |
| 3. Yanping Dai, Xiaoqin Gao. (2025) AKT2/mTOR/VEGF Signaling Attenuates Aging-Related Male Infertility by Suppressing Epididymal Autophagy and Apoptosis via Extracellular Vesicle-Mediated Sperm Rescue. FASEB JOURNAL, 39 (16): (e70901). [PMID:40810376] [10.1096/fj.202500818R] |
| 4. Wang Bingxiang, Zhao Ningning, Sun Lingyu, Tan Qianqian, Xiao Qianqian, Chen Junpeng, Li Jinxuan, Zhang Xiao, Zhao Xiaomin. (2023) A candidate virulence factor of Eimeria tenella (EtROP30) predicted by virulence enhancement of transgenic Toxoplasma gondii. PARASITOLOGY RESEARCH, 123 (1): (1-6). [PMID:38095706] [10.1007/s00436-023-08079-9] |
| 5. Xiangyang Li, Linru Chen, Xiaoyue Zeng, Kaixin Wu, Jiayu Huang, Mengmeng Liao, Yue Xi, Guohui Zhu, Xiuying Zeng, Xuewen Hou, Zhisheng Zhang, Xinxiang Peng. (2023) Wounding induces a peroxisomal H2O2 decrease via glycolate oxidase-catalase switch dependent on glutamate receptor-like channel-supported Ca2+ signaling in plants. PLANT JOURNAL, [PMID:37596913] [10.1111/tpj.16427] |
| 6. Feng Yuqing, Lu Jinfang, Peng Xujun, Ge Yanni, Zhang Ran, Li Huiling. (2023) Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis. MOLECULAR MEDICINE, 29 (1): (1-17). [PMID:36653745] [10.1186/s10020-022-00591-5] |
| 7. Zhifen Wu, Jian Pan, Jurong Yang, Dongshan Zhang. (2022) LncRNA136131 suppresses apoptosis of renal tubular epithelial cells in acute kidney injury by targeting the miR-378a-3p/Rab10 axis. Aging-US, [PMID:35482482] [10.18632/aging.204036] |
| 8. Lixiao Zhou, Ziying Yu, Yinyin Xia, Shuqun Cheng, Jieying Gao, Wei Sun, Xuejun Jiang, Jun Zhang, Lejiao Mao, Xia Qin, Zhen Zou, Jingfu Qiu, Chengzhi Chen. (2022) Repression of autophagy leads to acrosome biogenesis disruption caused by a sub-chronic oral administration of polystyrene nanoparticles. ENVIRONMENT INTERNATIONAL, [PMID:35381522] [10.1016/j.envint.2022.107220] |
| 9. Wu Binxin, Gao Furong, Lin Jianhua, Lu Lixia, Xu Huiming, Xu Guo-Tong. (2021) Conditioned Medium of Human Amniotic Epithelial Cells Alleviates Experimental Allergic Conjunctivitis Mainly by IL-1ra and IL-10. Frontiers in Immunology, [PMID:34880869] [10.3389/fimmu.2021.774601] |
| 10. Yan Lin, Meng Zhang, Tianxing Lin, Luying Wang, Guanggao Wang, Tianbao Chen, Songkun Su. (2021) Royal jelly from different floral sources possesses distinct wound-healing mechanisms and ingredient profiles. Food & Function, 12 (23): (12059-12076). [PMID:34783324] [10.1039/D1FO00586C] |
| 11. Xuke Yang, Jichao Yang, Mengyu Lyu, Yaqiong Li, Anqi Liu, Bang Shen. (2024) The α subunit of AMP-activated protein kinase is critical for the metabolic success and tachyzoite proliferation of Toxoplasma gondii. Microbial Biotechnology, 17 (4): (e14455). [PMID:38635138] [10.1111/1751-7915.14455] |
| 12. Yanni Ge, Ran Zhang, Yuqing Feng, Huiling Li. (2020) Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury. Molecular Therapy-Nucleic Acids, [PMID:32074940] [10.1016/j.omtn.2020.01.011] |
| 13. Zhen Peng, Yimin Cheng. (2026) Hexavalent Chromium Inhibits Human Sperm Motility by Targeting Lysine Glutarylation and Mitochondrial Function. JOURNAL OF APPLIED TOXICOLOGY, [PMID:41500245] [10.1002/jat.70043] |
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View Moligand™ grade guide →
