ANGPTL

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  1. Evinacumab (anti-ANGPTL3), INHIBITOR of Angiopoietin-related protein 3 inhibitor
    CAS: 1446419-85-7
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab169262
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ANGPTL3
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG4SP
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    Recombinant Evinacumab Antibody | Anti-ANGPTL3 Reference Antibody | Evinacumab | REGN1500 | Evinacumab(anti-ANGPTL3) ...
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Technical Details Quality & specification info on every product page
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Pack Size Options Multiple packaging sizes with pricing access from listing
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the ANGPTL listing put together?
It draws on reported ANGPTL annotations within Metabolic Enzyme/Protease and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an ANGPTL modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the ANGPTL entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for ANGPTL compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For ANGPTL work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the ANGPTL compound I need is not listed?
Search by CAS number or SMILES first, since analogs of ANGPTL compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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