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Apelin Receptor (APJ)

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  1. ML 221, Antagonist of apelin receptor
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    ML 221, Antagonist of apelin receptor
    CAS: 877636-42-5 Formula: C17H11N3O6S Molecular Weight: 385.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M286930
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    Technical Identifiers
    IUPAC Name
    [4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate
    SMILES
    C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    UASIRTUMPRQVFY-UHFFFAOYSA-N
    InChI
    1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2
    Synonyms
    5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one | ML221 | 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4...
  2. Apelin-36 (rat, mouse)
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    Apelin-36 (rat, mouse)
    CAS: 230299-95-3 PubChem CID: 131954568 Formula: C₁₈₅H₃₀₄N₆₈O₄₃S Molecular Weight: 4200.93
    ◐ .Made to order · 8–12 wks Item #: A288544
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    Technical Identifiers
    IUPAC Name
    2-[[1-[2-[[1-[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[1-[2-[[5-amino-2-[[2-[[2-[[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[5-amino-2-[[2-[2-[[2-[[1-[2-[[2-[[2-[[2-[[2-[show more
    SMILES
    CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NCC(=O)N2CCCC2C(=O)Nshow more
    InChIKey
    NRXGOOSANFUBIE-UHFFFAOYSA-N
    InChI
    1S/C185H304N68O43S/c1-98(2)82-109(189)148(266)246-144(100(5)6)172(290)238-122(46-21-24-67-188)174(292)251-78-35-58-135(251)169(287)235-119(53-31-74-21show more
  3. ELA-11 (human)
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    ELA-11 (human)
    CAS: 1784687-32-6 PubChem CID: 127043376 Formula: C58H90N16O13S2 Molecular Weight: 1283.57
    ◐ .Made to order · 8–12 wks Item #: E288238
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyshow more
    SMILES
    CC(C)CC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)N4CCCC4C(=O)O)NC(=O)C5CCCN5C(=O)C(CCSC)NCshow more
    InChIKey
    XXKPNJFJXZBRMX-HDKAIKTRSA-N
    InChI
    1S/C58H90N16O13S2/c1-32(2)25-39(68-52(81)43-16-10-21-72(43)54(83)38(19-24-89-5)66-47(76)36(59)30-88)49(78)67-40(27-35-28-62-31-64-35)50(79)70-42(29-75show more
  4. Apelin 17 TFA, Agonist of apelin receptor
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    Apelin 17 TFA, Agonist of apelin receptor
    CAS: 217082-57-0 PubChem CID: 118856244 Formula: C96H156N34O20S• XCF3COOH Molecular Weight: 2138.56（free basis）
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: A276194
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[[1-[2-[[1-[2-[[6-amino-2-[[2-[[2-[[2-[[2-[[1-[2-[[5-amino-2-[[5-carbamimidamido-2-[[5-carbamimidamido-2-[[2-(2,6-diaminohexanoylamino)-3-phenylpropshow more
    SMILES
    CC(C)CC(C(=O)NC(CO)C(=O)NC(CC1=CNC=N1)C(=O)NC(CCCCN)C(=O)NCC(=O)N2CCCC2C(=O)NC(CCSC)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)Cshow more
    InChIKey
    SVWSKJCJNAIKNH-UHFFFAOYSA-N
    InChI
    1S/C96H156N34O20S/c1-55(2)47-67(83(140)127-71(53-131)86(143)125-69(50-58-51-109-54-115-58)85(142)116-60(26-11-13-38-98)78(135)114-52-76(133)128-43-18-show more
    Synonyms
    Apelin-17 (human, bovine) TFA
  5. Apelin 13
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    Apelin 13
    CAS: 217082-58-1 Formula: C69H111N23O16S Molecular Weight: 1550.84
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A422612
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylidshow more
    SMILES
    CC(C)CC(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NCC(=O)N2CCCC2C(=O)NC(CCSC)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)Cshow more
    InChIKey
    XXCCRHIAIBQDPX-PEWBXTNBSA-N
    InChI
    1S/C69H111N23O16S/c1-39(2)32-47(86-58(98)44(17-9-26-78-68(73)74)83-63(103)52-20-12-29-91(52)65(105)45(18-10-27-79-69(75)76)84-56(96)42(71)22-23-54(72)show more
  6. ML 221, Antagonist of apelin receptor
    Wish List Compare
    ML 221, Antagonist of apelin receptor
    CAS: 877636-42-5 Formula: C17H11N3O6S Molecular Weight: 385.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M426631
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate
    SMILES
    C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    UASIRTUMPRQVFY-UHFFFAOYSA-N
    InChI
    1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2
    Synonyms
    5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one
  7. [Pyr1]-Apelin-13 trifluoroacetate salt, Agonist of apelin receptor
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    [Pyr1]-Apelin-13 trifluoroacetate salt, Agonist of apelin receptor
    CAS: 217082-60-5 PubChem CID: 25085173 Formula: C69H108N22O16S · xC2HF3O2 Molecular Weight: 分子量:1533.80 (free base basis）
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: P275806
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylidshow more
    SMILES
    CC(C)CC(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(CCCCN)C(=O)NCC(=O)N2CCCC2C(=O)NC(CCSC)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)Cshow more
    InChIKey
    GGMAXEWLXWJGSF-PEWBXTNBSA-N
    InChI
    1S/C69H108N22O16S/c1-39(2)32-47(85-57(96)43(17-9-26-76-68(71)72)82-63(102)52-20-12-29-90(52)65(104)45(18-10-27-77-69(73)74)83-58(97)44-22-23-54(93)80-show more
    Synonyms
    (Glp1)-Apelin-13, human, bovine | Pyr-apelin-13 | (Pyr1)-Apelin-13 (human, bovine, mouse, rat) trifluoroacetate (H-Py...
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Frequently Asked Questions

How is the Apelin Receptor (APJ) listing put together?
It draws on reported Apelin Receptor (APJ) annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Apelin Receptor (APJ) modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Apelin Receptor (APJ) entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Apelin Receptor (APJ) compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Apelin Receptor (APJ) work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Apelin Receptor (APJ) compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Apelin Receptor (APJ) compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.
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