Apoptosis

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  1. Zoledronic Acid Disodium Salt Tetrahydrate
    CAS: 165800-07-7 PubChem CID: 21123000 Formula: C5H8N2Na2O7P2.4H2O Molecular Weight: 388.11
    ◐ .Made to order · 8–12 wks Item #: Z275198
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    IUPAC Name
    disodium;(1-hydroxy-2-imidazol-1-yl-1-phosphonatoethyl)phosphonic acid;tetrahydrate
    SMILES
    C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)([O-])[O-].O.O.O.O.[Na+].[Na+]
    InChIKey
    IEJZOPBVBXAOBH-UHFFFAOYSA-L
    InChI
    1S/C5H10N2O7P2.2Na.4H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;;;;;;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);;;4*1H2/q;2*+1;;;;/p-2
    Synonyms
    Zoledronate Disodium | CGP-42446A | Zoledronate disodium salt
  2. Ritonavir, Cytochrome P450 3A inhibitor
    CAS: 155213-67-5 EC Number: 605-001-5 Formula: C37H48N6O5S2 Molecular Weight: 720.94
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R126586
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    IUPAC Name
    1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,show more
    SMILES
    CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
    InChIKey
    NCDNCNXCDXHOMX-XGKFQTDJSA-N
    InChI
    1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-2show more
    Synonyms
    2,4,7,12-Tetraazatridecan-13-oic acid, 10-hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-di...
  3. AEE788 (NVP-AEE788), Vascular endothelial growth factor receptor 1 inhibitor
    CAS: 497839-62-0 Formula: C27H32N6 Molecular Weight: 440.58
    ● In Stock — US warehouse, ships to EU* Item #: A126830
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    IUPAC Name
    6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
    SMILES
    CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4NC(C)C5=CC=CC=C5
    InChIKey
    OONFNUWBHFSNBT-HXUWFJFHSA-N
    InChI
    1S/C27H32N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,17,19-20H,3,13-16,18H2,1-2show more
    Synonyms
    6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[3,2-e]pyrimidin-4-amine | 7,9-Dimethyl-...
  4. GDC-0068, Serine/threonine-protein kinase AKT inhibitor
    CAS: 1001264-89-6 Formula: C24H32ClN5O2 Molecular Weight: 458
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: G127588
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    IUPAC Name
    (2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one
    SMILES
    CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
    InChIKey
    GRZXWCHAXNAUHY-NSISKUIASA-N
    InChI
    1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3show more
    Synonyms
    RG7440 | GDC0068 | GDC 0068 | RG-7440 | RG 7440 | DTXSID9041152 | Ipatasertib; GDC-0068 | NCGC00182063-03 | AS-17027 ...
  5. NVP-ADW742
    CAS: 475488-23-4 Formula: C28H31N5O Molecular Weight: 453.58
    ● In Stock — US warehouse, ships to EU* Item #: N126810
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    IUPAC Name
    5-(3-phenylmethoxyphenyl)-7-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
    SMILES
    C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
    InChIKey
    LSFLAQVDISHMNB-UHFFFAOYSA-N
    InChI
    1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23Hshow more
    Synonyms
    5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | AS-56233 |...
  6. Licofelone
    CAS: 156897-06-2 EC Number: 694-581-3 Formula: C23H22ClNO2 Molecular Weight: 379.88
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: L129298
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    IUPAC Name
    2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid
    SMILES
    CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C
    InChIKey
    UAWXGRJVZSAUSZ-UHFFFAOYSA-N
    InChI
    1S/C23H22ClNO2/c1-23(2)13-19-22(15-6-4-3-5-7-15)21(16-8-10-17(24)11-9-16)18(12-20(26)27)25(19)14-23/h3-11H,12-14H2,1-2H3,(H,26,27)
    Synonyms
    ML-3000 | 2,2-Dimethyl-6-(4-chlorophenyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)acetic acid | 2,3-Dihydro-6-(4-chlo...
  7. Lidocaine hydrochloride
    CAS: 73-78-9 Formula: C14H22N2O.HCl Molecular Weight: 270.8
    ● In Stock — US warehouse, ships to EU* Item #: L276132
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    IUPAC Name
    2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride
    SMILES
    CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl
    InChIKey
    IYBQHJMYDGVZRY-UHFFFAOYSA-N
    InChI
    1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
    Synonyms
    Rucaina hydrochloride | Xilina hydrochloride | Xyloneural | Lidocaine hydrochloride | Lidothesin | Xycaine hydrochlor...
  8. Linalool, Activator of TRPM8
    CAS: 78-70-6 EC Number: 201-134-4 Formula: C10H18O Molecular Weight: 154.25
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: L106905
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    IUPAC Name
    3,7-dimethylocta-1,6-dien-3-ol
    SMILES
    CC(=CCCC(C)(C=C)O)C
    InChIKey
    CDOSHBSSFJOMGT-UHFFFAOYSA-N
    InChI
    1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3
    Synonyms
    LINALOOL [FHFI] | NCGC00091688-03 | WLN: 1U1XQ1&3UY1&1 | (1)-3,7-Dimethyl-1,6-octadien-3-ol | EPA Pesticide Chemical ...
  9. GW441756
    CAS: 504433-23-2 Formula: C17H13N3O Molecular Weight: 275.3
    ● In Stock — US warehouse, ships to EU* Item #: G129825
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    IUPAC Name
    (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
    SMILES
    CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
    InChIKey
    NXNQLECPAXXYTR-LCYFTJDESA-N
    InChI
    1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
    Synonyms
    GW441756 hydrochloride | 3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one | BRD-K04146668-...
  10. Zinc protoporphyrin
    CAS: 15442-64-5 PubChem CID: 439935 Formula: C34H32N4O4Zn Molecular Weight: 626.03
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: Z282553
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    IUPAC Name
    zinc;3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,23-diid-2-yl]propanoic acid
    SMILES
    CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C(=C3CCC(=O)O)C)CCC(=O)O.[Zn+2]
    InChIKey
    FUTVBRXUIKZACV-UHFFFAOYSA-L
    InChI
    1S/C34H34N4O4.Zn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;show more
    Synonyms
    Zinc protoporphyrin | Protoporphyrin IX zinc(II), guanylate cyclase inhibitor | C03184 | MFCD00011612 | PROTOPORPHYRI...
  11. Ginkgolide B, Channel blocker of 5-HT 3A;Channel blocker of 5-HT 3AB;Channel blocker of glycine receptor α1 subunit;Channel blocker of glycine receptor α2 subunit;Channel blocker of glycine receptor α3 subunit;Channel blocker of glycine receptor β subunit;Antagonist of
    CAS: 15291-77-7 EC Number: 604-876-0 Formula: C20H24O10 Molecular Weight: 424.4
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: G101969
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    IUPAC Name
    8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
    SMILES
    CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O
    InChIKey
    SQOJOAFXDQDRGF-UHFFFAOYSA-N
    InChI
    1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3
    Synonyms
    Ginkgolide B | Ginkolide B | Ginklide B | 1-Hydroxy-(1beta)-Ginkgolide A | Gingko lactone | 7-Deoxyginkgolide C | BN-...
  12. Zerumbone
    CAS: 471-05-6 PubChem CID: 5470187 Formula: C15H22O Molecular Weight: 218.33
    ● In Stock — US warehouse, ships to EU* Item #: Z275052
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    IUPAC Name
    (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
    SMILES
    CC1=CCC(C=CC(=O)C(=CCC1)C)(C)C
    InChIKey
    GIHNTRQPEMKFKO-SKTNYSRSSA-N
    InChI
    1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
    Synonyms
    C20262 | erumbone | BDBM50241296 | Zerumbone | MS-23207 | SCHEMBL12831266 | SRCZ-00151 | HB4130 | CCG-208558 | (E,E,E...
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Frequently Asked Questions

How is the Apoptosis listing put together?
It draws on reported Apoptosis annotations within Apoptosis and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Apoptosis modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Apoptosis entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Apoptosis compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Apoptosis work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Apoptosis compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Apoptosis compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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