Autophagy

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  1. Sertaconazole nitrate, Cytochrome P450 51 inhibitor
    CAS: 99592-39-9 PubChem CID: 200103 Formula: C20H15Cl3N2OS·HNO3 Molecular Weight: 500.78
    ● In Stock — US warehouse, ships to EU* Item #: S129395
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    IUPAC Name
    1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
    SMILES
    C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-]
    InChIKey
    HAAITRDZHUANGT-UHFFFAOYSA-N
    InChI
    1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)
    Synonyms
    HMS1571A12 | CAS-99592-39-9 | A851341 | 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H...
  2. GSK2126458 (GSK458), Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
    CAS: 1086062-66-9 EC Number: 629-873-1 Formula: C25H17F2N5O3S Molecular Weight: 505.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: G127233
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    IUPAC Name
    2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide
    SMILES
    COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
    InChIKey
    CGBJSGAELGCMKE-UHFFFAOYSA-N
    InChI
    1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3
    Synonyms
    A25172 | CHEBI:95093 | HMS3656D09 | N-[2-Methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide | ...
  3. GSK690693, Protein kinase C (PKC) inhibitor
    CAS: 937174-76-0 EC Number: 804-554-1 Formula: C21H27N7O3 Molecular Weight: 425.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: G127527
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    IUPAC Name
    4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3S)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
    SMILES
    CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
    InChIKey
    KGPGFQWBCSZGEL-ZDUSSCGKSA-N
    InChI
    1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,2show more
    Synonyms
    (R)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-yl-MeO)-1H-imidazo[4,5-c]pyridin-4-yl)-2-Me-but-3-yn-2...
  4. Retinoic acid
    CAS: 302-79-4 EC Number: 206-129-0 Formula: C20H28O2 Molecular Weight: 300.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R106320
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    IUPAC Name
    (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
    SMILES
    CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
    InChIKey
    SHGAZHPCJJPHSC-YCNIQYBTSA-N
    InChI
    1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
    Synonyms
    (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid | TRETINOIN COMPONENT OF...
  5. Nimodipine, Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2;Gating inhibitor of Ca v1.3;Gating inhibitor of Ca v1.4;Activator of CFTR;Antagonist of Mineralocorticoid receptor;Allosteric modulator of P2X4
    CAS: 66085-59-4 EC Number: 266-127-0 Formula: C21H26N2O7 Molecular Weight: 418.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N129506
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    3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
    InChIKey
    UIAGMCDKSXEBJQ-UHFFFAOYSA-N
    InChI
    1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
    Synonyms
    Nimodipine ap | SPECTRUM1503600 | 2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-d...
  6. N-octanoyl-D-erythro-sphingosine
    CAS: 74713-59-0 Formula: C26H51NO3 Molecular Weight: 425.688
    ● In Stock — US warehouse, ships to EU* Item #: N130616
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    IUPAC Name
    N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]octanamide
    SMILES
    CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
    InChIKey
    APDLCSPGWPLYEQ-WRBRXSDHSA-N
    InChI
    1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21show more
    Synonyms
    BSPBio_001569 | HMS1361O11 | N-octanoylsphing-4-enine | SCHEMBL14020687 | DTXSID701318293 | SR-01000946565 | N-Octano...
  7. Zoledronic Acid Disodium Salt Tetrahydrate
    CAS: 165800-07-7 PubChem CID: 21123000 Formula: C5H8N2Na2O7P2.4H2O Molecular Weight: 388.11
    ◐ .Made to order · 8–12 wks Item #: Z275198
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    IUPAC Name
    disodium;(1-hydroxy-2-imidazol-1-yl-1-phosphonatoethyl)phosphonic acid;tetrahydrate
    SMILES
    C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)([O-])[O-].O.O.O.O.[Na+].[Na+]
    InChIKey
    IEJZOPBVBXAOBH-UHFFFAOYSA-L
    InChI
    1S/C5H10N2O7P2.2Na.4H2O/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7;;;;;;/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14);;;4*1H2/q;2*+1;;;;/p-2
    Synonyms
    Zoledronate Disodium | CGP-42446A | Zoledronate disodium salt
  8. Nicardipine hydrochloride
    CAS: 54527-84-3 EC Number: 259-198-4 Formula: C26H29N3O6·HCl Molecular Weight: 515.99
    ● In Stock — US warehouse, ships to EU* Item #: N129547
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    IUPAC Name
    5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl
    InChIKey
    AIKVCUNQWYTVTO-UHFFFAOYSA-N
    InChI
    1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16Hshow more
    Synonyms
    Nicardipine (Hydrochloride) | NICARDIPINE HYDROCHLORIDE [MI] | HMS1569M07 | Loxen | MLS001146898 | NICARDIPINE HYDROC...
  9. Linagliptin, Dipeptidyl peptidase IV inhibitor
    CAS: 668270-12-0 EC Number: 620-351-9 Formula: C25H28N8O2 Molecular Weight: 472.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: L127331
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    IUPAC Name
    8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
    SMILES
    CC#CCN1C2=C(N=C1N3CCCC(C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
    InChIKey
    LTXREWYXXSTFRX-QGZVFWFLSA-N
    InChI
    1S/C25H28N8O2/c1-4-5-13-32-21-22(29-24(32)31-12-8-9-17(26)14-31)30(3)25(35)33(23(21)34)15-20-27-16(2)18-10-6-7-11-19(18)28-20/h6-7,10-11,17H,8-9,12-15show more
    Synonyms
    BI 1356 | 8-((3R)-3-AMINOPIPERIDIN-1-YL)-7-(BUT-2-YN-1-YL)-3-METHYL-1-((4-METHYLQUINAZOLIN-2-YL)METHYL)-3,7-DIHYDRO-1...
  10. Licochalcone A
    CAS: 58749-22-7 EC Number: 635-678-2 Formula: C21H22O4 Molecular Weight: 338.4
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: L139040
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    IUPAC Name
    (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
    SMILES
    CC(C)(C=C)C1=C(C=C(C(=C1)C=CC(=O)C2=CC=C(C=C2)O)OC)O
    InChIKey
    KAZSKMJFUPEHHW-DHZHZOJOSA-N
    InChI
    1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+
    Synonyms
    BDBM50068270 | CHEBI:125689 | MFCD01417903 | SCHEMBL114042 | (2E)-3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-metho...
  11. Zebularine
    CAS: 3690-10-6 PubChem CID: 100016 Formula: C9H12N2O5 Molecular Weight: 228.20
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: Z135482
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    IUPAC Name
    1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
    SMILES
    C1=CN(C(=O)N=C1)C2C(C(C(O2)CO)O)O
    InChIKey
    RPQZTTQVRYEKCR-WCTZXXKLSA-N
    InChI
    1S/C9H12N2O5/c12-4-5-6(13)7(14)8(16-5)11-3-1-2-10-9(11)15/h1-3,5-8,12-14H,4H2/t5-,6-,7-,8-/m1/s1
    Synonyms
    PYRIMIDIN-2-ONE .BETA.-D-RIBOFURANOSIDE | 1-beta-D-Ribofuranosyl-2(1H)-pyrimidino ne | 1-Pentofuranosylpyrimidin-2(1H...
  12. ZSTK474, PI3-kinase class I inhibitor
    CAS: 475110-96-4 PubChem CID: 11647372 Formula: C19H21F2N7O2 Molecular Weight: 417.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Z126804
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    IUPAC Name
    4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
    SMILES
    C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5
    InChIKey
    HGVNLRPZOWWDKD-UHFFFAOYSA-N
    InChI
    1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
    Synonyms
    BRD-K63068307-001-01-4 | TCMDC-137004 | 4,4''-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diy...
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Frequently Asked Questions

Which compounds are listed for Autophagy?
Compounds associated with Autophagy are grouped here under the Autophagy classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Autophagy sit within Autophagy?
Autophagy is one target listing within the Autophagy classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Autophagy?
For compounds listed under Autophagy, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Autophagy?
Browse the parent Autophagy listing to reach targets neighbouring Autophagy, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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