Calcium Channel

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  1. GSK-1016790A, Activator of TRPV4
    CAS: 942206-85-1 Formula: C28H32Cl2N4O6S2 Molecular Weight: 655.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: G275374
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    IUPAC Name
    N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
    SMILES
    CC(C)CC(C(=O)N1CCN(CC1)C(=O)C(CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3
    InChIKey
    IVYQPSHHYIAUFO-VXKWHMMOSA-N
    InChI
    1S/C28H32Cl2N4O6S2/c1-17(2)13-21(31-26(36)24-14-18-5-3-4-6-23(18)41-24)27(37)33-9-11-34(12-10-33)28(38)22(16-35)32-42(39,40)25-8-7-19(29)15-20(25)30/hshow more
    Synonyms
    GSK101 | HY-19608 | GSK 1016790A | N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]pipera...
  2. Lomerizine Dihydrochloride
    CAS: 101477-54-7 PubChem CID: 122125 Formula: C27H30F2N2O3·2HCl Molecular Weight: 541.46
    ● In Stock — US warehouse, ships to EU* Item #: L157774
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    IUPAC Name
    1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
    SMILES
    COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl
    InChIKey
    LOGVKVSFYBBUAJ-UHFFFAOYSA-N
    InChI
    1S/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3show more
    Synonyms
    101477-54-7, 101477-55-8(free base) | Tox21_112172 | Lomerizine Dihydrochloride, 98% | Terranas (TN) | DTXCID9026427 ...
  3. Nemadipine A
    CAS: 54280-71-6 EC Number: 637-254-2 Formula: C19H18F5NO4 Molecular Weight: 419.34
    ◐ .Made to order · 8–12 wks Item #: N275975
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    IUPAC Name
    diethyl 2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CCOC(=O)C1=C(NC(=C(C1C2=C(C(=C(C(=C2F)F)F)F)F)C(=O)OCC)C)C
    InChIKey
    QABNLWXKUCMDBP-UHFFFAOYSA-N
    InChI
    1S/C19H18F5NO4/c1-5-28-18(26)9-7(3)25-8(4)10(19(27)29-6-2)11(9)12-13(20)15(22)17(24)16(23)14(12)21/h11,25H,5-6H2,1-4H3
    Synonyms
    Diethyl2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  4. Nimodipine, Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2;Gating inhibitor of Ca v1.3;Gating inhibitor of Ca v1.4;Activator of CFTR;Antagonist of Mineralocorticoid receptor;Allosteric modulator of P2X4
    CAS: 66085-59-4 EC Number: 266-127-0 Formula: C21H26N2O7 Molecular Weight: 418.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N129506
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    IUPAC Name
    3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
    InChIKey
    UIAGMCDKSXEBJQ-UHFFFAOYSA-N
    InChI
    1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
    Synonyms
    Nimodipine ap | SPECTRUM1503600 | 2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-d...
  5. Nicardipine, Antagonist of A 3 receptor;Channel blocker of K v1.4
    CAS: 55985-32-5 EC Number: 259-932-3 Formula: C26H29N3O6 Molecular Weight: 479.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N275193
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    IUPAC Name
    5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
    InChIKey
    ZBBHBTPTTSWHBA-UHFFFAOYSA-N
    InChI
    1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4show more
    Synonyms
    Bio1_001066 | IDI1_000540 | KBio2_006988 | KBio3_002443 | Dagan | SCHEMBL34277 | YC-93 free base | CAS-55985-32-5 | C...
  6. Nicardipine hydrochloride
    CAS: 54527-84-3 EC Number: 259-198-4 Formula: C26H29N3O6·HCl Molecular Weight: 515.99
    ● In Stock — US warehouse, ships to EU* Item #: N129547
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    IUPAC Name
    5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl
    InChIKey
    AIKVCUNQWYTVTO-UHFFFAOYSA-N
    InChI
    1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16Hshow more
    Synonyms
    Nicardipine (Hydrochloride) | NICARDIPINE HYDROCHLORIDE [MI] | HMS1569M07 | Loxen | MLS001146898 | NICARDIPINE HYDROC...
  7. Zonisamide-d4
    CAS: 1020720-04-0 PubChem CID: 45040707 Formula: C8H4D4N2O3S Molecular Weight: 216.25
    ● In Stock — US warehouse, ships to EU* Item #: Z334653
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    IUPAC Name
    (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide
    SMILES
    C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N
    InChIKey
    UBQNRHZMVUUOMG-RHQRLBAQSA-N
    InChI
    1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)/i1D,2D,3D,4D
    Synonyms
    1-[(~2~H_4_)-1,2-Benzoxazol-3-yl]methanesulfonamide | 3-(Sulfamoylmethyl)-1,2-benzisoxazole-d4 | 1020720-04-0 | 1,2-B...
  8. N106
    CAS: 862974-25-2 Formula: C17H14N4O3S Molecular Weight: 354.38
    ● In Stock — US warehouse, ships to EU* Item #: N287217
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    IUPAC Name
    N-(4-methoxy-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
    SMILES
    COC1=CC=C(C=C1)C2=NN=C(O2)NC3=NC4=C(C=CC=C4S3)OC
    InChIKey
    FBCSWQRNKAYAGY-UHFFFAOYSA-N
    InChI
    1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H,1-2H3,(H,18,19,21)
    Synonyms
    4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine | N-106
  9. Lercanidipine hydrochloride hemihydrate, Voltage-gated L-type calcium channel blocker
    CAS: 132866-11-6 Formula: C36H41N3O6 · HCl · 0.5H2O Molecular Weight: 657.2
    ● In Stock — US warehouse, ships to EU* Item #: L122339
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    IUPAC Name
    5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochlshow more
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
    InChIKey
    WMFYOYKPJLRMJI-UHFFFAOYSA-N
    InChI
    1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12show more
    Synonyms
    CAS-132866-11-6 | 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophe...
  10. NS-638
    CAS: 150493-34-8 Formula: C15H11ClF3N3 Molecular Weight: 325.72
    ● In Stock — US warehouse, ships to EU* Item #: N302954
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    IUPAC Name
    1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine
    SMILES
    C1=CC(=CC=C1CN2C3=C(C=C(C=C3)C(F)(F)F)N=C2N)Cl
    InChIKey
    GXQCVUZORDAARJ-UHFFFAOYSA-N
    InChI
    1S/C15H11ClF3N3/c16-11-4-1-9(2-5-11)8-22-13-6-3-10(15(17,18)19)7-12(13)21-14(22)20/h1-7H,8H2,(H2,20,21)
    Synonyms
    AKOS032947353 | 2-Amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole | 1H-Benzimidazol-2-amine, 1-((4-chlorophen...
  11. Taurolithocholic Acid-d5 Sodium Salt (Major)
    CAS: 1265476-97-8 PubChem CID: 46782976 Formula: C26H39D5NNaO5S Molecular Weight: 510.72
    ≥95%,≥95 atom% D Deuterated from d0-d6
    ◐ .Made to order · 8–12 wks Item #: T358194
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    Technical Identifiers
    IUPAC Name
    sodium;2-[[(4R)-4-[(3R,5R,8R,10S,13R,14S)-2,2,3,4,4-pentadeuterio-3-hydroxy-10,13-dimethyl-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenashow more
    SMILES
    CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C.[Na+]
    InChIKey
    YAERYJYXPRIDTO-SDXLJUFPSA-M
    InChI
    1S/C26H45NO5S.Na/c1-17(4-9-24(29)27-14-15-33(30,31)32)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3;/h17-23,28H,4-16H2,1-3H3,(H,27show more
    Synonyms
    2-[[(3α,5β)-3-Hydroxy-24-oxocholan-24-yl-d5]amino]ethanesulfonic Acid Sodium Salt | N-(3α-Hydroxy-5β-cholan-24-oyl)ta...
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Frequently Asked Questions

How is the Calcium Channel listing put together?
It draws on reported Calcium Channel annotations within Membrane Transporter/Ion Channel and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Calcium Channel modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Calcium Channel entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Calcium Channel compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Calcium Channel work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Calcium Channel compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Calcium Channel compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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