CaMK

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  1. GSK-3 Inhibitor XIII, Inhibitor of aurora kinase A;Inhibitor of glycogen synthase kinase 3 beta;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinase
    CAS: 404828-08-6 Formula: C18H19N5 Molecular Weight: 305.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: G338805
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    Synonyms
    (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine
  2. TX-1123
    CAS: 157397-06-3 PubChem CID: 403661 Formula: C20H24O3 Molecular Weight: 312.4
    ◐ .Made to order · 8–12 wks Item #: T339226
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    IUPAC Name
    2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione
    SMILES
    CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O
    InChIKey
    VUEUMQIBGLKJJD-UHFFFAOYSA-N
    InChI
    1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3
    Synonyms
    2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
  3. K-252a
    CAS: 99533-80-9 EC Number: 640-127-4 Formula: C27H21N3O5 Molecular Weight: 467.47
    Solid ≥97%(HPLC)
    ◐ .Made to order · 8–12 wks Item #: K139531
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    IUPAC Name
    methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,2show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O
    InChIKey
    KOZFSFOOLUUIGY-SOLYNIJKSA-N
    InChI
    1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11show more
    Synonyms
    K 252 | methyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]...
  4. A 484954
    CAS: 142557-61-7 EC Number: 802-826-4 Formula: C13H15N5O3 Molecular Weight: 289.29
    ● In Stock — US warehouse, ships to EU* Item #: A288912
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    IUPAC Name
    7-amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
    SMILES
    CCN1C(=O)C2=CC(=C(N=C2N(C1=O)C3CC3)N)C(=O)N
    InChIKey
    HWODCHXORCTEGU-UHFFFAOYSA-N
    InChI
    1S/C13H15N5O3/c1-2-17-12(20)8-5-7(10(15)19)9(14)16-11(8)18(13(17)21)6-3-4-6/h5-6H,2-4H2,1H3,(H2,14,16)(H2,15,19)
    Synonyms
    7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide | A 484954 | HY-11009...
  5. Syntide 2
    CAS: 108334-68-5 PubChem CID: 5748289 Formula: C68H122N20O18 Molecular Weight: 1507.82
    ● In Stock — US warehouse, ships to EU* Item #: S118927
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    IUPAC Name
    (2S)-6-amino-2-[[(2S)-6-amino-2-[[2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2show more
    SMILES
    CC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCC(=O)NC(show more
    InChIKey
    NKBRRWBNPNUBDD-TYKVATLISA-N
    InChI
    1S/C68H122N20O18/c1-35(2)29-46(83-57(95)42-21-16-26-73-42)60(98)77-40(10)56(94)81-44(22-17-27-74-68(71)72)59(97)87-54(41(11)90)65(103)84-47(30-36(3)4)show more
    Synonyms
    Pro-leu-ala-arg-thr-leu-ser-val-ala-gly-leu-pro-gly-lys-lys | Syntide-2, Protein Kinase Substrate | DTXSID70148504 | ...
  6. A-3 hydrochloride
    CAS: 78957-85-4 EC Number: 636-054-2 Formula: C12H14Cl2N2O2S Molecular Weight: 321.22
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ◐ .Made to order · 8–12 wks Item #: A276438
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    IUPAC Name
    N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride
    SMILES
    C1=CC2=C(C=CC=C2Cl)C(=C1)S(=O)(=O)NCCN.Cl
    InChIKey
    VWAGIWCLJAQLAL-UHFFFAOYSA-N
    InChI
    1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H
    Synonyms
    Tox21_501027 | FT-0645250 | NCGC00094317-01 | N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride | LP01...
  7. AR 420626
    CAS: 1798310-55-0 Formula: C21H18Cl2N2O3 Molecular Weight: 417.29
    ● In Stock — US warehouse, ships to EU* Item #: A287232
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    IUPAC Name
    N-(2,5-dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide
    SMILES
    CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl
    InChIKey
    GGTYQECCGLBHGS-UHFFFAOYSA-N
    InChI
    1S/C21H18Cl2N2O3/c1-11-18(21(27)25-15-10-12(22)7-8-13(15)23)20(17-6-3-9-28-17)19-14(24-11)4-2-5-16(19)26/h3,6-10,20,24H,2,4-5H2,1H3,(H,25,27)
    Synonyms
    N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide | AR420626
  8. W-13 hydrochloride
    CAS: 88519-57-7 PubChem CID: 16760706 Formula: C14H17ClN2O2S•HCl Molecular Weight: 349.27
    ● In Stock — US warehouse, ships to EU* Item #: W288803
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    IUPAC Name
    N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide;hydrochloride
    SMILES
    C1=CC2=C(C=CC(=C2)S(=O)(=O)NCCCCN)C(=C1)Cl.Cl
    InChIKey
    QKAALLVQBOLELJ-UHFFFAOYSA-N
    InChI
    1S/C14H17ClN2O2S.ClH/c15-14-5-3-4-11-10-12(6-7-13(11)14)20(18,19)17-9-2-1-8-16;/h3-7,10,17H,1-2,8-9,16H2;1H
    Synonyms
    N-(4-aminobutyl)-5-chloro-2-naphthalene sulfonamide hydro chloride | N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonami...
  9. STO609, Inhibitor of calcium/calmodulin dependent protein kinase kinase 1;Inhibitor of calcium/calmodulin dependent protein kinase kinase 2
    CAS: 52029-86-4 PubChem CID: 3467590 Formula: C19H10N2O3 Molecular Weight: 314.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: S395991
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    IUPAC Name
    11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
    InChIKey
    MYKOWOGZBMOVBJ-UHFFFAOYSA-N
    InChI
    1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24)
    Synonyms
    11-oxo-3,10-diazapentacyclo[10.7.1.02,10.04,9.016,20]icosa-1(20),2,4,6,8,12,14,16,18-nonaene-17-carboxylic acid | 7H-...
  10. KN-62, Allosteric modulator of P2X7
    CAS: 127191-97-3 Formula: C38H35N5O6S2 Molecular Weight: 721.84
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: K125637
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    IUPAC Name
    [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-5-sulfonate
    SMILES
    CN(C(CC1=CC=C(C=C1)OS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C(=O)N4CCN(CC4)C5=CC=CC=C5)S(=O)(=O)C6=CC=CC7=C6C=CN=C7
    InChIKey
    RJVLFQBBRSMWHX-DHUJRADRSA-N
    InChI
    1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37show more
    Synonyms
    KN62 | KN-62 | MFCD00083180 | NCGC00162398-03 | [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylp...
  11. KN-93, Inhibitor of calcium/calmodulin-dependent protein kinase II alpha subunit
    CAS: 139298-40-1 Formula: C26H29ClN2O4S Molecular Weight: 599.03
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: K125309
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    IUPAC Name
    N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
    SMILES
    CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC
    InChIKey
    LLLQTDSSHZREGW-AATRIKPKSA-N
    InChI
    1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+
    Synonyms
    AMY3402 | (2-[N -(2-hydroxyethyl)]-N -(4-methoxybenzenesulfonyl)]amino-N -(4-chlorocinnamyl)-N -methylbenzylamine) | ...
  12. Trifluoperazine Dihydrochloride, Serotonin 2c (5-HT2c) receptor antagonist
    CAS: 440-17-5 EC Number: 207-123-0 PubChem CID: 66064 Formula: C21H24F3N3S·2HCl Molecular Weight: 480.42
    ● In Stock — US warehouse, ships to EU* Item #: T162449
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    IUPAC Name
    10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;dihydrochloride
    SMILES
    CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl
    InChIKey
    BXDAOUXDMHXPDI-UHFFFAOYSA-N
    InChI
    1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
    Synonyms
    D00799 | EU-0101232 | AI3-50137 | Jatroneural | MFCD00012656 | NSC17474 | Triphthasine | EN300-122645 | FT-0600798 | ...
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Frequently Asked Questions

How is the CaMK listing put together?
It draws on reported CaMK annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CaMK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CaMK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CaMK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CaMK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CaMK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CaMK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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