CD73

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  1. Adenosine 5'-(α,β-methylene)diphosphate sodium salt
    CAS: 89016-30-8 Formula: C11H16N5NaO9P2 Molecular Weight: 447.21
    ◐ .Made to order · 8–12 wks Item #: A286760
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    Technical Identifiers
    IUPAC Name
    sodium;[[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methyl-hydroxyphosphinate
    SMILES
    C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(CP(=O)(O)[O-])O)O)O)N.[Na+]
    InChIKey
    RFGZKSPLJPHQMI-RDJRRFHDSA-M
    InChI
    1S/C11H17N5O9P2.Na/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(show more
    Synonyms
    AMPCP, APCP | α,β-Methyleneadenosine 5'-diphosphate monosodium salt
  2. LY-3475070
    CAS: 2375815-63-5 Formula: C15H18N4O2 Molecular Weight: 286.33
    ● In Stock — US warehouse, ships to EU* Item #: L414499
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    Technical Identifiers
    IUPAC Name
    5-[6-methyl-5-[(1S,2R)-2-propan-2-ylcyclopropyl]pyridazin-3-yl]-1H-pyrimidine-2,4-dione
    SMILES
    CC1=NN=C(C=C1C2CC2C(C)C)C3=CNC(=O)NC3=O
    InChIKey
    WHRUIISQCORGKK-KOLCDFICSA-N
    InChI
    1S/C15H18N4O2/c1-7(2)9-4-11(9)10-5-13(19-18-8(10)3)12-6-16-15(21)17-14(12)20/h5-7,9,11H,4H2,1-3H3,(H2,16,17,20,21)/t9-,11+/m1/s1
  3. Mupadolimab (anti-CD73), Antibody of Ecto-5'-Nucleotidase
    CAS: 2451856-97-4
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170487
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    Technical Identifiers
    Associated targets
    NT5E
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    5' nucleotidase (CD73) | 5'-NT | 5-NT | 5'-Nucleotidase | 5'-nucleotidase, ecto (CD73) | CD73 antigen | CD73 | E5NT |...
  4. Oleclumab (anti-CD73), Antibody of Ecto-5'-Nucleotidase
    CAS: 1803176-05-7
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170578
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    NT5E
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    5'-NT | EC 3.1.3.5 | Ecto-5'-nucleotidase
  5. AB680, Inhibitor of Ecto-5'-Nucleotidase
    CAS: 2105904-82-1 PubChem CID: 130205852 Formula: C20H24ClFN4O9P2 Molecular Weight: 580.82
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: A607317
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    Technical Identifiers
    IUPAC Name
    [[(2R,3S,4R,5R)-5-[6-chloro-4-[[(1S)-1-(2-fluorophenyl)ethyl]amino]pyrazolo[3,4-b]pyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]metshow more
    SMILES
    CC(C1=CC=CC=C1F)NC2=CC(=NC3=C2C=NN3C4C(C(C(O4)COP(=O)(CP(=O)(O)O)O)O)O)Cl
    InChIKey
    MFYLCAMJNGIULC-KCVUFLITSA-N
    InChI
    1S/C20H24ClFN4O9P2/c1-10(11-4-2-3-5-13(11)22)24-14-6-16(21)25-19-12(14)7-23-26(19)20-18(28)17(27)15(35-20)8-34-37(32,33)9-36(29,30)31/h2-7,10,15,17-18show more
    Synonyms
    UNII-J6K8WSV73A | [[(2~{R},3~{S},4~{R},5~{R})-5-[6-chloranyl-4-[[(1~{S})-1-(2-fluorophenyl)ethyl]amino]pyrazolo[3,4-b...
  6. Adenosine 5′-(α,β-methylene)diphosphate, Inhibitor of Ecto-5'-Nucleotidase
    CAS: 3768-14-7 PubChem CID: 92199 Formula: C11H17N5O9P2 Molecular Weight: 425.23
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: M607522
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    Technical Identifiers
    IUPAC Name
    [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid
    SMILES
    Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]3O
    InChIKey
    OLCWZBFDIYXLAA-IOSLPCCCSA-N
    InChI
    1S/C11H17N5O9P2/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,1show more
    Synonyms
    AMP-CP | AMPCP | 5'-O-[(R)-hydroxy(phosphonomethyl)phosphoryl]adenosine | [4-(4-propylcyclohexyl)phenyl]boronic acid ...
  7. CD73-IN-4
    CAS: 2216764-29-1 PubChem CID: 135348940 Formula: C16H23ClN5O7P Molecular Weight: 463.81
    ◐ .Made to order · 8–12 wks Item #: C647604
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    Technical Identifiers
    IUPAC Name
    [(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethylphosphonic acid
    SMILES
    C1CCC(C1)NC2=C3C=NN(C3=NC(=N2)Cl)C4C(C(C(O4)COCP(=O)(O)O)O)O
    InChIKey
    IVHVIBKVJIZKOC-RTWAVKEYSA-N
    InChI
    1S/C16H23ClN5O7P/c17-16-20-13(19-8-3-1-2-4-8)9-5-18-22(14(9)21-16)15-12(24)11(23)10(29-15)6-28-7-30(25,26)27/h5,8,10-12,15,23-24H,1-4,6-7H2,(H,19,20,2show more
  8. CD73-IN-1
    CAS: 2132396-40-6 PubChem CID: 130406413 Formula: C18H17N3O4S Molecular Weight: 371.41
    ◐ .Made to order · 8–12 wks Item #: C649018
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    Technical Identifiers
    IUPAC Name
    5-[(2-cyclopropyl-1H-indol-6-yl)sulfamoyl]-2-hydroxybenzamide
    SMILES
    C1CC1C2=CC3=C(N2)C=C(C=C3)NS(=O)(=O)C4=CC(=C(C=C4)O)C(=O)N
    InChIKey
    YUGALILHRFUCAY-UHFFFAOYSA-N
    InChI
    1S/C18H17N3O4S/c19-18(23)14-9-13(5-6-17(14)22)26(24,25)21-12-4-3-11-7-15(10-1-2-10)20-16(11)8-12/h3-10,20-22H,1-2H2,(H2,19,23)
  9. PSB-12379
    CAS: 1802226-78-3 PubChem CID: 122207761 Formula: C18H23N5O9P2 Molecular Weight: 515.35
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: P649737
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [[(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid
    SMILES
    C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)COP(=O)(CP(=O)(O)O)O)O)O
    InChIKey
    DMBYYIJBPDWQFF-SCFUHWHPSA-N
    InChI
    1S/C18H23N5O9P2/c24-14-12(7-31-34(29,30)10-33(26,27)28)32-18(15(14)25)23-9-22-13-16(20-8-21-17(13)23)19-6-11-4-2-1-3-5-11/h1-5,8-9,12,14-15,18,24-25H,show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for CD73?
Compounds associated with CD73 are grouped here under the Immunology/Inflammation classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does CD73 sit within Immunology/Inflammation?
CD73 is one target listing within the Immunology/Inflammation classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from CD73?
For compounds listed under CD73, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for CD73?
Browse the parent Immunology/Inflammation listing to reach targets neighbouring CD73, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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