CDK

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  1. CDK5 inhibitor 20-223
    CAS: 865317-30-2 PubChem CID: 69761759 Formula: C19H19N3O Molecular Weight: 305.37
    ◐ .Made to order · 8–12 wks Item #: C647987
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    IUPAC Name
    N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-naphthalen-2-ylacetamide
    SMILES
    C1CC(C1)C2=CC(=NN2)NC(=O)CC3=CC4=CC=CC=C4C=C3
    InChIKey
    AGVIDDQHAQSPIZ-UHFFFAOYSA-N
    InChI
    1S/C19H19N3O/c23-19(20-18-12-17(21-22-18)15-6-3-7-15)11-13-8-9-14-4-1-2-5-16(14)10-13/h1-2,4-5,8-10,12,15H,3,6-7,11H2,(H2,20,21,22,23)
  2. WEE1-IN-5
    CAS: 2243882-74-6 Formula: C26H28Cl2N6O Molecular Weight: 511.45
    ◐ .Made to order · 8–12 wks Item #: W648831
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    SMILES
    O=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
  3. BGG463
    CAS: 890129-26-7 PubChem CID: 67406169 Formula: C30H29F3N6O3 Molecular Weight: 578.58
    ◐ .Made to order · 8–12 wks Item #: B648906
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    IUPAC Name
    6-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
    SMILES
    CC(=O)NC1=CC(=NC=N1)OC2=CC3=C(C=C2)C(=CC=C3)C(=O)NC4=CC(=C(C=C4)CN5CCN(CC5)C)C(F)(F)F
    InChIKey
    MZZJNOOADWVFPD-UHFFFAOYSA-N
    InChI
    1S/C30H29F3N6O3/c1-19(40)36-27-16-28(35-18-34-27)42-23-8-9-24-20(14-23)4-3-5-25(24)29(41)37-22-7-6-21(26(15-22)30(31,32)33)17-39-12-10-38(2)11-13-39/hshow more
  4. Casein Kinase inhibitor A51
    CAS: 2079068-74-7 PubChem CID: 126558497 Formula: C18H25ClN6 Molecular Weight: 360.88
    ◐ .Made to order · 8–12 wks Item #: C649030
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    IUPAC Name
    4-N-[5-chloro-4-[5-(cyclopropylmethyl)-1-methylpyrazol-4-yl]pyrimidin-2-yl]cyclohexane-1,4-diamine
    SMILES
    CN1C(=C(C=N1)C2=NC(=NC=C2Cl)NC3CCC(CC3)N)CC4CC4
    InChIKey
    RVZJFCNYSSUDCU-UHFFFAOYSA-N
    InChI
    1S/C18H25ClN6/c1-25-16(8-11-2-3-11)14(9-22-25)17-15(19)10-21-18(24-17)23-13-6-4-12(20)5-7-13/h9-13H,2-8,20H2,1H3,(H,21,23,24)
  5. CDK8-IN-1
    CAS: 1629633-48-2 PubChem CID: 86274989 Formula: C11H8F3N3O Molecular Weight: 255.20
    ◐ .Made to order · 8–12 wks Item #: C649452
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    IUPAC Name
    4-pyridin-4-yl-3-(trifluoromethyl)-1H-pyrrole-2-carboxamide
    SMILES
    C1=CN=CC=C1C2=CNC(=C2C(F)(F)F)C(=O)N
    InChIKey
    RKTPHHQXNCHBCF-UHFFFAOYSA-N
    InChI
    1S/C11H8F3N3O/c12-11(13,14)8-7(5-17-9(8)10(15)18)6-1-3-16-4-2-6/h1-5,17H,(H2,15,18)
  6. ABC1183
    CAS: 1042735-18-1 PubChem CID: 134500787 Formula: C18H14N4OS Molecular Weight: 334.39
    ◐ .Made to order · 8–12 wks Item #: A649618
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    IUPAC Name
    4-[4-amino-2-(4-methylanilino)-1,3-thiazole-5-carbonyl]benzonitrile
    SMILES
    CC1=CC=C(C=C1)NC2=NC(=C(S2)C(=O)C3=CC=C(C=C3)C#N)N
    InChIKey
    CUDLEXBIVZPJBU-UHFFFAOYSA-N
    InChI
    1S/C18H14N4OS/c1-11-2-8-14(9-3-11)21-18-22-17(20)16(24-18)15(23)13-6-4-12(10-19)5-7-13/h2-9H,20H2,1H3,(H,21,22)
    Synonyms
    BCP30547 | Benzonitrile, 4-[[4-amino-2-[(4-methylphenyl)amino]-5-thiazolyl]carbonyl]- | ABC1183 | ABC-1183 | SB18692 ...
  7. CP-10
    CAS: 2366268-80-4 EC Number: 958-152-7 PubChem CID: 138911323 Formula: C44H49N13O7 Molecular Weight: 871.94
    ◐ .Made to order · 8–12 wks Item #: C650023
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    IUPAC Name
    4-[2-[2-[4-[[4-[6-[(6-acetyl-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]pyridin-3-yl]piperazin-1-yl]methyl]triazol-1-yl]ethoxy]ethyshow more
    SMILES
    CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCN(CC4)CC5=CN(N=N5)CCOCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O)C9CCCC9)C(=O)C
    InChIKey
    PACRWHUPEPCFHX-UHFFFAOYSA-N
    InChI
    1S/C44H49N13O7/c1-26-32-23-47-44(50-39(32)56(29-6-3-4-7-29)42(62)37(26)27(2)58)48-35-12-10-30(22-46-35)54-17-15-53(16-18-54)24-28-25-55(52-51-28)19-21show more
  8. PROTAC CDK9 Degrader-1
    CAS: 2118356-96-8 PubChem CID: 132472236 Formula: C33H35N5O7 Molecular Weight: 613.7
    ◐ .Made to order · 8–12 wks Item #: P650019
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    Technical Identifiers
    IUPAC Name
    N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-[4-[5-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxypentoxy]phenyl]acetamide
    SMILES
    C1CC(C1)C2=CC(=NN2)NC(=O)CC3=CC=C(C=C3)OCCCCCOC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O
    InChIKey
    WCEHIDWONYOKOJ-UHFFFAOYSA-N
    InChI
    1S/C33H35N5O7/c39-28-15-14-25(31(41)35-28)38-32(42)23-8-5-9-26(30(23)33(38)43)45-17-3-1-2-16-44-22-12-10-20(11-13-22)18-29(40)34-27-19-24(36-37-27)21-show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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