CDK

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  1. JH-XI-10-02
    CAS: 2209085-22-1 PubChem CID: 133081965 Formula: C53H69N5O9 Molecular Weight: 920.14
    ◐ .Made to order · 8–12 wks Item #: J647710
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    IUPAC Name
    3-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-N-[(3S,8R,10S,13S,14S,17S)-17-isoquinolin-7-yl-1show more
    SMILES
    CC12CCC(CC1CCC3C2CCC4(C3CCC4C5=CC6=C(C=C5)C=CN=C6)C)N(C)C(=O)CCOCCOCCOCCOCCNC7=CC=CC8=C7C(=O)N(C8=O)C9CCC(=O)NC9=O
    InChIKey
    JECHBTRAPARMGI-KMIZWFMDSA-N
    InChI
    1S/C53H69N5O9/c1-52-19-15-38(32-37(52)9-10-39-42-12-11-41(53(42,2)20-16-43(39)52)35-8-7-34-17-21-54-33-36(34)31-35)57(3)47(60)18-23-64-25-27-66-29-30-show more
  2. CDK12-IN-3
    CAS: 2220184-50-7 Formula: C23H28F2N8O Molecular Weight: 470.52
    ◐ .Made to order · 8–12 wks Item #: C647924
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    IUPAC Name
    2-[(2S)-1-[6-[(4,5-difluoro-1H-benzimidazol-2-yl)methylamino]-9-propan-2-ylpurin-2-yl]piperidin-2-yl]ethanol
    SMILES
    CC(C)N1C=NC2=C(N=C(N=C21)N3CCCCC3CCO)NCC4=NC5=C(N4)C=CC(=C5F)F
    InChIKey
    KULPPFCRBINTBS-AWEZNQCLSA-N
    InChI
    1S/C23H28F2N8O/c1-13(2)33-12-27-20-21(26-11-17-28-16-7-6-15(24)18(25)19(16)29-17)30-23(31-22(20)33)32-9-4-3-5-14(32)8-10-34/h6-7,12-14,34H,3-5,8-11H2,show more
  3. CCT-251921
    CAS: 1607837-31-9 PubChem CID: 74222277 Formula: C21H23ClN6O Molecular Weight: 410.90
    Solid ≥98%
    ◐ .Made to order · 8–12 wks Item #: C647937
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    IUPAC Name
    8-[2-amino-3-chloro-5-(1-methylindazol-5-yl)pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
    SMILES
    CN1C2=C(C=C(C=C2)C3=CN=C(C(=C3N4CCC5(CCNC5=O)CC4)Cl)N)C=N1
    InChIKey
    VPJXPDLMACOGIZ-UHFFFAOYSA-N
    InChI
    1S/C21H23ClN6O/c1-27-16-3-2-13(10-14(16)11-26-27)15-12-25-19(23)17(22)18(15)28-8-5-21(6-9-28)4-7-24-20(21)29/h2-3,10-12H,4-9H2,1H3,(H2,23,25)(H,24,29)
    Synonyms
    8-(2-Amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one
  4. NCT02
    CAS: 790245-61-3 EC Number: 840-752-4 PubChem CID: 2501755 Formula: C17H16N2O2S Molecular Weight: 312.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: N648209
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    Synonyms
    2-(6,7-Dihydro-5H-indeno[5,6-b]furan-3-yl)-N-(5-methylthiazol-2-yl)acetamide
  5. (-)-Enitociclib
    CAS: 1610358-59-2 Formula: C19H18F2N4O2S Molecular Weight: 404.43
    ◐ .Made to order · 8–12 wks Item #: E648346
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    IUPAC Name
    5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine
    SMILES
    COC1=C(C=CC(=C1)F)C2=CC(=NC=C2F)NC3=NC=CC(=C3)CS(=N)(=O)C
    InChIKey
    YZCUMZWULWOUMD-UHFFFAOYSA-N
    InChI
    1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)
    Synonyms
    (+)-BAY-1251152 | BR164331 | (-)-5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]-2-pyridin...
  6. AMG 925 HCl
    CAS: 1401034-19-2 PubChem CID: 121371122 Formula: C26H30ClN7O2 Molecular Weight: 508.02
    ◐ .Made to order · 8–12 wks Item #: A648345
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    IUPAC Name
    2-hydroxy-1-[2-[[8-(4-methylcyclohexyl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-yl]amino]-7,8-dihydro-5H-1,6-naphthyridishow more
    SMILES
    CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5.Cl
    InChIKey
    JJDSFFVYZSLRLY-UHFFFAOYSA-N
    InChI
    1S/C26H29N7O2.ClH/c1-16-2-5-18(6-3-16)33-22-13-27-10-8-19(22)20-12-28-26(31-25(20)33)30-23-7-4-17-14-32(24(35)15-34)11-9-21(17)29-23;/h4,7-8,10,12-13,show more
  7. DIF-3
    CAS: 113411-17-9 PubChem CID: 3081033 Formula: C13H17ClO4 Molecular Weight: 272.72
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: D648796
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    IUPAC Name
    1-(3-chloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
    SMILES
    CCCCCC(=O)C1=C(C(=C(C=C1O)OC)Cl)O
    InChIKey
    JWBMZIJMSBFBIY-UHFFFAOYSA-N
    InChI
    1S/C13H17ClO4/c1-3-4-5-6-8(15)11-9(16)7-10(18-2)12(14)13(11)17/h7,16-17H,3-6H2,1-2H3
    Synonyms
    J-002961 | Dif-3 (dictyostelium) | Differentiation-inducing factor 3 | DTXSID50150408 | HY-145669 | 1-(3-chloro-2,6-d...
  8. LY3177833
    CAS: 1627696-51-8 PubChem CID: 81689696 Formula: C16H12FN5O Molecular Weight: 309.30
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: L648774
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    IUPAC Name
    (3R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)-2H-isoindol-1-one
    SMILES
    CC1(C2=C(C=C(C=C2)C3=CNN=C3)C(=O)N1)C4=NC=NC=C4F
    InChIKey
    KNLVLWZENYQYRT-MRXNPFEDSA-N
    InChI
    1S/C16H12FN5O/c1-16(14-13(17)7-18-8-19-14)12-3-2-9(10-5-20-21-6-10)4-11(12)15(23)22-16/h2-8H,1H3,(H,20,21)(H,22,23)/t16-/m1/s1
  9. KB-0742 dihydrochloride
    CAS: 2416874-75-2 PubChem CID: 155819527 Formula: C16H27Cl2N5 Molecular Weight: 360.33
    ◐ .Made to order · 8–12 wks Item #: K649087
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    IUPAC Name
    (1S,3S)-3-N-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine;dihydrochloride
    SMILES
    CCC(CC)C1=NC2=CC=NN2C(=C1)NC3CCC(C3)N.Cl.Cl
    InChIKey
    OTUPXOLLHVLWQF-NJHZPMQHSA-N
    InChI
    1S/C16H25N5.2ClH/c1-3-11(4-2)14-10-16(19-13-6-5-12(17)9-13)21-15(20-14)7-8-18-21;;/h7-8,10-13,19H,3-6,9,17H2,1-2H3;2*1H/t12-,13-;;/m0../s1
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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