CX3CR1

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  1. Alirocumab (anti-PCSK9)
    CAS: 1245916-14-6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% 75mg/ml in buffer
    ● In Stock — US warehouse, ships to EU* Item #: A302291
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    PCSK9
    Reactive species
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    C(C(COP(=O)(O)O)O)O.[Na].[Na]
    InChIKey
    CATWCRUATKKAAQ-UHFFFAOYSA-N
    InChI
    1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
    Synonyms
    BCP25199 | CID 88214187 | 1245916-14-6 | B0084-007210 | SCHEMBL7870957 | BA165582
  2. JMS-17-2, Antagonist of CX 3CR1
    CAS: 1380392-05-1 Formula: C25H26ClN3O Molecular Weight: 419.95
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: J412197
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    Technical Identifiers
    IUPAC Name
    5-[3-[4-(4-chlorophenyl)piperidin-1-yl]propyl]pyrrolo[1,2-a]quinoxalin-4-one
    SMILES
    C1CN(CCC1C2=CC=C(C=C2)Cl)CCCN3C4=CC=CC=C4N5C=CC=C5C3=O
    InChIKey
    WOSMCMULWWHMIV-UHFFFAOYSA-N
    InChI
    1S/C25H26ClN3O/c26-21-10-8-19(9-11-21)20-12-17-27(18-13-20)14-4-16-29-23-6-2-1-5-22(23)28-15-3-7-24(28)25(29)30/h1-3,5-11,15,20H,4,12-14,16-18H2
    Synonyms
    5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one
  3. JMS-17-2, Antagonist of CX 3CR1
    CAS: 1380392-05-1 Formula: C25H26ClN3O Molecular Weight: 419.95
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: J421437
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    Technical Identifiers
    IUPAC Name
    5-[3-[4-(4-chlorophenyl)piperidin-1-yl]propyl]pyrrolo[1,2-a]quinoxalin-4-one
    SMILES
    C1CN(CCC1C2=CC=C(C=C2)Cl)CCCN3C4=CC=CC=C4N5C=CC=C5C3=O
    InChIKey
    WOSMCMULWWHMIV-UHFFFAOYSA-N
    InChI
    1S/C25H26ClN3O/c26-21-10-8-19(9-11-21)20-12-17-27(18-13-20)14-4-16-29-23-6-2-1-5-22(23)28-15-3-7-24(28)25(29)30/h1-3,5-11,15,20H,4,12-14,16-18H2
    Synonyms
    5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one
  4. Alirocumab (anti-PCSK9), Antibody of proprotein convertase subtilisin/kexin type 9
    CAS: 1245916-14-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab169266
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    PCSK9
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    C(C(COP(=O)(O)O)O)O.[Na].[Na]
    InChIKey
    CATWCRUATKKAAQ-UHFFFAOYSA-N
    InChI
    1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
    Synonyms
    Recombinant Alirocumab Antibody | REGN 727 | SAR 236553 | Alirocumab (anti-PCSK9) | Anti-PCSK9 Reference Antibody (al...
  5. AZD8797
    CAS: 911715-90-7 PubChem CID: 11965767 Formula: C19H25N5OS2 Molecular Weight: 403.56
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A649378
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    Technical Identifiers
    IUPAC Name
    (2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
    SMILES
    CC(C)CC(CO)NC1=NC(=NC2=C1SC(=N2)N)SC(C)C3=CC=CC=C3
    InChIKey
    ZMQSLMZOWVGBSM-GXTWGEPZSA-N
    InChI
    1S/C19H25N5OS2/c1-11(2)9-14(10-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,25H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t1show more
    Synonyms
    (R)-2-((2-Amino-5-(((S)-1-phenylethyl)thio)thiazolo[4,5-d]pyrimidin-7-yl)amino)-4-methylpentan-1-ol | (2R)-2-[[2-amin...
  6. E6130
    CAS: 1427058-33-0 PubChem CID: 71293692 Formula: C28H37ClF3N3O3 Molecular Weight: 556.06
    ◐ .Made to order · 8–12 wks Item #: E651519
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[(3S,4R)-1-[[2-chloro-6-(trifluoromethyl)phenyl]methyl]-3-[[1-(cyclohexen-1-ylmethyl)piperidin-4-yl]carbamoyl]-4-methylpyrrolidin-3-yl]acetic acid
    SMILES
    CC1CN(CC1(CC(=O)O)C(=O)NC2CCN(CC2)CC3=CCCCC3)CC4=C(C=CC=C4Cl)C(F)(F)F
    InChIKey
    JTJKDYLEMNXXER-UZTOHYMASA-N
    InChI
    1S/C28H37ClF3N3O3/c1-19-15-35(17-22-23(28(30,31)32)8-5-9-24(22)29)18-27(19,14-25(36)37)26(38)33-21-10-12-34(13-11-21)16-20-6-3-2-4-7-20/h5-6,8-9,19,21show more
    Synonyms
    1427058-33-0 | CHC05833 | HY-107456 | SCHEMBL14760920 | E6130 | 2-[(3S,4R)-1-{[2-Chloro-6-(trifluoromethyl)phenyl]met...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under CX3CR1?
This listing collects compounds associated with CX3CR1 within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CX3CR1?
Consider the reported potency of each CX3CR1 compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CX3CR1 compounds?
Each CX3CR1 product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CX3CR1 compounds by activity or structure?
Yes. Filter the CX3CR1 listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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