CXCR

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  1. Decursin
    CAS: 5928-25-6 Formula: C19H20O5 Molecular Weight: 328.36
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: D424943
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    IUPAC Name
    [(3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] 3-methylbut-2-enoate
    SMILES
    CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C
    InChIKey
    CUKSFECWKQBVED-INIZCTEOSA-N
    InChI
    1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
    Synonyms
    2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b')dipyran-7-yl ester, (S)- | Ambap5...
  2. Kynurenic acid, Agonist of GPR35
    CAS: 492-27-3 EC Number: 207-751-5 Formula: C10H7NO3 Molecular Weight: 189.17
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: K424259
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    IUPAC Name
    4-oxo-1H-quinoline-2-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
    InChIKey
    HCZHHEIFKROPDY-UHFFFAOYSA-N
    InChI
    1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
    Synonyms
    AMY18102 | BDBM81975 | Oprea1_032085 | Tox21_500716 | HCZHHEIFKROPDY-UHFFFAOYSA- | LP00716 | KYA | 4-Hydroxy-2-quinol...
  3. MSX-127
    CAS: 6616-56-4 EC Number: 663-907-6 Formula: C16H24N2O4 Molecular Weight: 308.37
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M425330
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    IUPAC Name
    2,5-bis(morpholin-4-ylmethyl)benzene-1,4-diol
    SMILES
    C1COCCN1CC2=CC(=C(C=C2O)CN3CCOCC3)O
    InChIKey
    DGGCIZWVIVXHFR-UHFFFAOYSA-N
    InChI
    1S/C16H24N2O4/c19-15-10-14(12-18-3-7-22-8-4-18)16(20)9-13(15)11-17-1-5-21-6-2-17/h9-10,19-20H,1-8,11-12H2
    Synonyms
    MSX-127NSC23026 | A913780 | HY-103009 | Oprea1_481211 | 2,5-Bis(4-morpholinylmethyl)-1,4-benzenediol # | AE-848/31997...
  4. MSX-130
    CAS: 4051-59-6 Formula: C36H26N4 Molecular Weight: 514.62
    2mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: M423853
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    Technical Identifiers
    IUPAC Name
    2-[4-(4,5-diphenyl-1H-imidazol-2-yl)phenyl]-4,5-diphenyl-1H-imidazole
    SMILES
    C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C4=NC(=C(N4)C5=CC=CC=C5)C6=CC=CC=C6)C7=CC=CC=C7
    InChIKey
    MKRQQXYFSWSAIS-UHFFFAOYSA-N
    InChI
    1S/C36H26N4/c1-5-13-25(14-6-1)31-32(26-15-7-2-8-16-26)38-35(37-31)29-21-23-30(24-22-29)36-39-33(27-17-9-3-10-18-27)34(40-36)28-19-11-4-12-20-28/h1-24Hshow more
    Synonyms
    1H-​Imidazole,2,​2'-​(1,​4-​phenylene)​bis[4,​5-​diphenyl-
  5. MSX-122, C-X-C chemokine receptor type 4 antagonist
    CAS: 897657-95-3 Formula: C16H16N6 Molecular Weight: 292.34
    ● In Stock — US warehouse, ships to EU* Item #: M413551
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    Technical Identifiers
    IUPAC Name
    N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]pyrimidin-2-amine
    SMILES
    C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
    InChIKey
    PXZXYRKDDXKDTK-UHFFFAOYSA-N
    InChI
    1S/C16H16N6/c1-7-17-15(18-8-1)21-11-13-3-5-14(6-4-13)12-22-16-19-9-2-10-20-16/h1-10H,11-12H2,(H,17,18,21)(H,19,20,22)
    Synonyms
    Q27264343 | XKB65795 | UNII-69D634Q702 | BDBM194510 | DB12715 | N,N'-(1,4-phenylenebis(methylene))bis(pyrimidin-2-ami...
  6. MSX-127
    CAS: 6616-56-4 Formula: C16H24N2O4 Molecular Weight: 308.37
    ● In Stock — US warehouse, ships to EU* Item #: M412305
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    Technical Identifiers
    IUPAC Name
    2,5-bis(morpholin-4-ylmethyl)benzene-1,4-diol
    SMILES
    C1COCCN1CC2=CC(=C(C=C2O)CN3CCOCC3)O
    InChIKey
    DGGCIZWVIVXHFR-UHFFFAOYSA-N
    InChI
    1S/C16H24N2O4/c19-15-10-14(12-18-3-7-22-8-4-18)16(20)9-13(15)11-17-1-5-21-6-2-17/h9-10,19-20H,1-8,11-12H2
    Synonyms
    MSX-127NSC23026 | A913780 | HY-103009 | Oprea1_481211 | 2,5-Bis(4-morpholinylmethyl)-1,4-benzenediol # | AE-848/31997...
  7. MSX-130
    CAS: 4051-59-6 Formula: C36H26N4 Molecular Weight: 514.62
    ● In Stock — US warehouse, ships to EU* Item #: M412306
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    Technical Identifiers
    IUPAC Name
    2-[4-(4,5-diphenyl-1H-imidazol-2-yl)phenyl]-4,5-diphenyl-1H-imidazole
    SMILES
    C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C4=NC(=C(N4)C5=CC=CC=C5)C6=CC=CC=C6)C7=CC=CC=C7
    InChIKey
    MKRQQXYFSWSAIS-UHFFFAOYSA-N
    InChI
    1S/C36H26N4/c1-5-13-25(14-6-1)31-32(26-15-7-2-8-16-26)38-35(37-31)29-21-23-30(24-22-29)36-39-33(27-17-9-3-10-18-27)34(40-36)28-19-11-4-12-20-28/h1-24Hshow more
    Synonyms
    1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene
  8. MSX-122, C-X-C chemokine receptor type 4 antagonist
    CAS: 897657-95-3 Formula: C16H16N6 Molecular Weight: 292.34
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M426733
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    Technical Identifiers
    IUPAC Name
    N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]pyrimidin-2-amine
    SMILES
    C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
    InChIKey
    PXZXYRKDDXKDTK-UHFFFAOYSA-N
    InChI
    1S/C16H16N6/c1-7-17-15(18-8-1)21-11-13-3-5-14(6-4-13)12-22-16-19-9-2-10-20-16/h1-10H,11-12H2,(H,17,18,21)(H,19,20,22)
    Synonyms
    Q27264343 | XKB65795 | UNII-69D634Q702 | BDBM194510 | DB12715 | N,N'-(1,4-phenylenebis(methylene))bis(pyrimidin-2-ami...
  9. Motixafortide (BL-8040)
    CAS: 664334-36-5 Formula: C97H144FN33O19S2 Molecular Weight: 2159.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    ◐ .Made to order · 8–12 wks Item #: M425344
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    IUPAC Name
    (3S,6S,9S,12S,15R,20R,23S,26S,29S,32S)-3,6-bis(4-aminobutyl)-N-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]-15-[[(2S)-2-[[(2S)-5-carbamimidamido-show more
    SMILES
    C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CC=C5C=show more
    InChIKey
    JJVZSYKFCOBILL-MKMRYRNGSA-N
    InChI
    1S/C97H144FN33O19S2/c98-60-33-31-58(32-34-60)78(135)119-65(19-8-42-113-93(104)105)79(136)121-68(21-10-44-115-95(108)109)83(140)126-73(51-56-25-30-57-1show more
    Synonyms
    CHEBI:145536 | L-ARGININAMIDE, N2-(4-FLUOROBENZOYL)-L-ARGINYL-L-ARGINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-CYSTEINYL-L-TYR...
  10. Navarixin (SCH-527123), Interleukin-8 receptor A antagonist
    CAS: 473727-83-2 Formula: C21H23N3O5 Molecular Weight: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N414035
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    IUPAC Name
    2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
    SMILES
    CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    InChIKey
    RXIUEIPPLAFSDF-CYBMUJFWSA-N
    InChI
    1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
    Synonyms
    Navarixin | SCH 527123,CAS:473727-83-2 | s8506 | (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-...
  11. Navarixin (SCH-527123), Interleukin-8 receptor A antagonist
    CAS: 473727-83-2 Formula: C21H23N3O5 Molecular Weight: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N424121
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    Technical Identifiers
    IUPAC Name
    2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
    SMILES
    CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    InChIKey
    RXIUEIPPLAFSDF-CYBMUJFWSA-N
    InChI
    1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
    Synonyms
    MK-7123 | PS-291822Benzamide,2-​hydroxy-​N,​N-​dimethyl-​3-​[[2-​[[(1R)​-​1-​(5-​methyl-​2-​furanyl)​propyl]​amino]​-�...
  12. Nicotinamide N-Oxide
    CAS: 1986-81-8 EC Number: 217-859-4 Formula: C6H6N2O2 Molecular Weight: 138.12
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N422414
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    Technical Identifiers
    IUPAC Name
    1-oxidopyridin-1-ium-3-carboxamide
    SMILES
    C1=CC(=C[N+](=C1)[O-])C(=O)N
    InChIKey
    USSFUVKEHXDAPM-UHFFFAOYSA-N
    InChI
    1S/C6H6N2O2/c7-6(9)5-2-1-3-8(10)4-5/h1-4H,(H2,7,9)
    Synonyms
    3-Pyridinecarboxamide, 1-oxide | Nicotinamide N-oxide | InChI=1/C6H6N2O2/c7-6(9)5-2-1-3-8(10)4-5/h1-4H,(H2,7,9) | Nic...
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Frequently Asked Questions

Which compounds are listed for CXCR?
Compounds associated with CXCR are grouped here under the GPCR/G Protein classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does CXCR sit within GPCR/G Protein?
CXCR is one target listing within the GPCR/G Protein classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from CXCR?
For compounds listed under CXCR, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for CXCR?
Browse the parent GPCR/G Protein listing to reach targets neighbouring CXCR, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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