CXCR

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  1. NBI-74330
    CAS: 855527-92-3 Formula: C32H27F4N5O3 Molecular Weight: 605.58
    ◐ .Made to order · 8–12 wks Item #: N646511
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    Technical Identifiers
    IUPAC Name
    N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide
    SMILES
    CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC(=C(C=C5)F)C(F)(F)F
    InChIKey
    XMRGQUDUVGRCBS-UHFFFAOYSA-N
    InChI
    1S/C32H27F4N5O3/c1-3-44-24-11-9-23(10-12-24)41-30(39-29-25(31(41)43)7-5-15-38-29)20(2)40(19-22-6-4-14-37-18-22)28(42)17-21-8-13-27(33)26(16-21)32(34,3show more
  2. Ladarixin, Interleukin-8 receptor B modulator
    CAS: 849776-05-2 PubChem CID: 11372270 Formula: C11H12F3NO6S2 Molecular Weight: 375.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: L647680
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    Technical Identifiers
    IUPAC Name
    [4-[(2R)-1-(methanesulfonamido)-1-oxopropan-2-yl]phenyl] trifluoromethanesulfonate
    SMILES
    C[C@H](C1=CC=C(C=C1)OS(=O)(=O)C(F)(F)F)C(=O)NS(=O)(=O)C
    InChIKey
    DDLPYOCJHQSVSZ-SSDOTTSWSA-N
    InChI
    1S/C11H12F3NO6S2/c1-7(10(16)15-22(2,17)18)8-3-5-9(6-4-8)21-23(19,20)11(12,13)14/h3-7H,1-2H3,(H,15,16)/t7-/m1/s1
    Synonyms
    Ladarixin | Q27276351 | CHEMBL189475 | 849776-05-2 (free) | DEH7Q6472O | AC6925 | LADARIXIN [WHO-DD] | A857904 | Lada...
  3. CXCR2-IN-2
    CAS: 1838123-21-9 PubChem CID: 100951623 Formula: C18H23ClN2O5S Molecular Weight: 414.90
    ◐ .Made to order · 8–12 wks Item #: C648383
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    IUPAC Name
    1-[4-chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea
    SMILES
    CC1=CCCC1NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)C3(CCOC3)C)O
    InChIKey
    DNXKACKCTLURQN-ACJLOTCBSA-N
    InChI
    1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,1show more
  4. AZD8797
    CAS: 911715-90-7 PubChem CID: 11965767 Formula: C19H25N5OS2 Molecular Weight: 403.56
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A649378
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    IUPAC Name
    (2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
    SMILES
    CC(C)CC(CO)NC1=NC(=NC2=C1SC(=N2)N)SC(C)C3=CC=CC=C3
    InChIKey
    ZMQSLMZOWVGBSM-GXTWGEPZSA-N
    InChI
    1S/C19H25N5OS2/c1-11(2)9-14(10-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,25H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t1show more
    Synonyms
    (R)-2-((2-Amino-5-(((S)-1-phenylethyl)thio)thiazolo[4,5-d]pyrimidin-7-yl)amino)-4-methylpentan-1-ol | (2R)-2-[[2-amin...
  5. SCH 546738
    CAS: 906805-42-3 PubChem CID: 11995774 Formula: C23H31Cl2N7O Molecular Weight: 492.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: S649861
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    Technical Identifiers
    IUPAC Name
    3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide
    SMILES
    CCC1CN(CCN1C2CCN(CC2)CC3=CC=C(C=C3)Cl)C4=NC(=C(N=C4Cl)C(=O)N)N
    InChIKey
    UYDYJFWSPRQEAX-KRWDZBQOSA-N
    InChI
    1S/C23H31Cl2N7O/c1-2-17-14-31(23-20(25)28-19(22(27)33)21(26)29-23)11-12-32(17)18-7-9-30(10-8-18)13-15-3-5-16(24)6-4-15/h3-6,17-18H,2,7-14H2,1H3,(H2,26show more
    Synonyms
    HY-10017 | AKOS016005318 | 3-Amino-6-chloro-5-((3S)-4-(1-((4-chlorophenyl)methyl)piperidin-4-yl)-3-ethylpiperazin-1-y...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for CXCR?
Compounds associated with CXCR are grouped here under the GPCR/G Protein classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does CXCR sit within GPCR/G Protein?
CXCR is one target listing within the GPCR/G Protein classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from CXCR?
For compounds listed under CXCR, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for CXCR?
Browse the parent GPCR/G Protein listing to reach targets neighbouring CXCR, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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