DAGL

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  1. RHC-80267, Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β
    CAS: 83654-05-1 PubChem CID: 5063 Formula: C20H34N4O4 Molecular Weight: 394.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R274741
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    IUPAC Name
    (cyclohexylideneamino) N-[6-[(cyclohexylideneamino)oxycarbonylamino]hexyl]carbamate
    SMILES
    C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
    InChIKey
    RXSVYGIGWRDVQC-UHFFFAOYSA-N
    InChI
    1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
    Synonyms
    BCBcMAP01_000181 | HMS3676J18 | HMS3268I22 | SCHEMBL23015112 | (Hexane-1,6-diyldiimino)bis{[(cyclohexylideneamino)oxy...
  2. RHC-80267, Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β
    CAS: 83654-05-1 PubChem CID: 5063 Formula: C20H34N4O4 Molecular Weight: 394.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R426166
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    Technical Identifiers
    IUPAC Name
    (cyclohexylideneamino) N-[6-[(cyclohexylideneamino)oxycarbonylamino]hexyl]carbamate
    SMILES
    C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
    InChIKey
    RXSVYGIGWRDVQC-UHFFFAOYSA-N
    InChI
    1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
    Synonyms
    BCBcMAP01_000181 | HMS3676J18 | HMS3268I22 | SCHEMBL23015112 | (Hexane-1,6-diyldiimino)bis{[(cyclohexylideneamino)oxy...
  3. KT-109, Inhibitor of αβ-Hydrolase 6;Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β
    CAS: 1402612-55-8 PubChem CID: 53364540 Formula: C27H26N4O Molecular Weight: 422.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: K611360
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    IUPAC Name
    (2-benzylpiperidin-1-yl)-[4-(4-phenylphenyl)triazol-1-yl]methanone
    SMILES
    C1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC=C5
    InChIKey
    JKJMWHULJIOKPJ-UHFFFAOYSA-N
    InChI
    1S/C27H26N4O/c32-27(30-18-8-7-13-25(30)19-21-9-3-1-4-10-21)31-20-26(28-29-31)24-16-14-23(15-17-24)22-11-5-2-6-12-22/h1-6,9-12,14-17,20,25H,7-8,13,18-1show more
    Synonyms
    KT109
  4. DO34, Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β
    CAS: 1848233-58-8 PubChem CID: 129188708 Formula: C26H28F3N5O4 Molecular Weight: 531.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: D609937
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    Technical Identifiers
    IUPAC Name
    tert-butyl 3-benzyl-4-[4-[4-(trifluoromethoxy)phenyl]triazole-1-carbonyl]piperazine-1-carboxylate
    SMILES
    CC(C)(C)OC(=O)N1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)OC(F)(F)F
    InChIKey
    CQGMWUWJVBKTRM-UHFFFAOYSA-N
    InChI
    1S/C26H28F3N5O4/c1-25(2,3)38-24(36)32-13-14-33(20(16-32)15-18-7-5-4-6-8-18)23(35)34-17-22(30-31-34)19-9-11-21(12-10-19)37-26(27,28)29/h4-12,17,20H,13-show more
    Synonyms
    DO-34
  5. Methanone, [4-(2'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl][2-(phenylMethyl)-1-piperidinyl]-
    CAS: 1402612-56-9 PubChem CID: 53364485 Formula: C28H28N4O2 Molecular Weight: 452.55
    ◐ .Made to order · 8–12 wks Item #: M1021379
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    Technical Identifiers
    IUPAC Name
    (2-benzylpiperidin-1-yl)-[4-[4-(2-methoxyphenyl)phenyl]triazol-1-yl]methanone
    SMILES
    COC1=CC=CC=C1C2=CC=C(C=C2)C3=CN(N=N3)C(=O)N4CCCCC4CC5=CC=CC=C5
    InChIKey
    MXVVJNJNDCJCFS-UHFFFAOYSA-N
    InChI
    1S/C28H28N4O2/c1-34-27-13-6-5-12-25(27)22-14-16-23(17-15-22)26-20-32(30-29-26)28(33)31-18-8-7-11-24(31)19-21-9-3-2-4-10-21/h2-6,9-10,12-17,20,24H,7-8,show more
  6. 2-[(2,2-Dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]acetic acid
    CAS: 1620582-23-1 Formula: C26H27NO6S Molecular Weight: 481.600
    ◐ .Made to order · 8–12 wks Item #: D957067
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    Technical Identifiers
    IUPAC Name
    2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]acetic acid
    SMILES
    CC1(CCC2=C(O1)C=CC(=C2)S(=O)(=O)N(CC3=CC=C(C=C3)OC4=CC=CC=C4)CC(=O)O)C
    InChIKey
    FOEGBOXMDBPYEV-UHFFFAOYSA-N
    InChI
    1S/C26H27NO6S/c1-26(2)15-14-20-16-23(12-13-24(20)33-26)34(30,31)27(18-25(28)29)17-19-8-10-22(11-9-19)32-21-6-4-3-5-7-21/h3-13,16H,14-15,17-18H2,1-2H3,show more
  7. Carbamic acid, N-(5-((2-phenylethyl)((4-(4-(trifluoromethoxy)phenyl)-1H-1,2,3-triazol-1-yl)carbonyl)amino)pentyl)-, 1,1-dimethylethyl ester
    CAS: 1402612-61-6 Formula: C28H34F3N5O4 Molecular Weight: 561.600
    ◐ .Made to order · 8–12 wks Item #: C963678
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    Technical Identifiers
    IUPAC Name
    tert-butyl N-[5-[2-phenylethyl-[4-[4-(trifluoromethoxy)phenyl]triazole-1-carbonyl]amino]pentyl]carbamate
    SMILES
    CC(C)(C)OC(=O)NCCCCCN(CCC1=CC=CC=C1)C(=O)N2C=C(N=N2)C3=CC=C(C=C3)OC(F)(F)F
    InChIKey
    NUWWTGPNHRKNPN-UHFFFAOYSA-N
    InChI
    1S/C28H34F3N5O4/c1-27(2,3)40-25(37)32-17-8-5-9-18-35(19-16-21-10-6-4-7-11-21)26(38)36-20-24(33-34-36)22-12-14-23(15-13-22)39-28(29,30)31/h4,6-7,10-15,show more
  8. DO34 analog
    CAS: 2098969-71-0 PubChem CID: 129201716
    ◐ .Made to order · 8–12 wks Item #: D1440523
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    Technical Identifiers
    IUPAC Name
    tert-butyl 3-benzyl-4-[4-[4-(trifluoromethoxy)phenyl]triazole-2-carbonyl]piperazine-1-carboxylate
    SMILES
    CC(C)(C)OC(=O)N1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3N=CC(=N3)C4=CC=C(C=C4)OC(F)(F)F
    InChIKey
    ZCLTTXIIPQGUKN-UHFFFAOYSA-N
    InChI
    1S/C26H28F3N5O4/c1-25(2,3)38-24(36)32-13-14-33(20(17-32)15-18-7-5-4-6-8-18)23(35)34-30-16-22(31-34)19-9-11-21(12-10-19)37-26(27,28)29/h4-12,16,20H,13-show more
  9. O-7460
    CAS: 1572051-31-0 PubChem CID: 132285144 Formula: C18H23ClINO3 Molecular Weight: 463.74
    ◐ .Made to order · 8–12 wks Item #: O1430818
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    IUPAC Name
    [1-[fluoro(methyl)phosphoryl]oxy-3-propan-2-yloxypropan-2-yl] (Z)-octadec-9-enoate
    SMILES
    CCCCCCCCC=CCCCCCCCC(=O)OC(COC(C)C)COP(=O)(C)F
    InChIKey
    ZLEFMXNNQCABDB-SEYXRHQNSA-N
    InChI
    1S/C25H48FO5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(27)31-24(21-29-23(2)3)22-30-32(4,26)28/h12-13,23-24H,5-11,14-22H2,1-4H3/b13-12-
  10. DO34
    CAS: 1848233-58-8 PubChem CID: 129188708 Formula: C26H28F3N5O4 Molecular Weight: 531.53
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: D1495095
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  11. KT109
    CAS: 1402612-55-8 EC Number: 110-028-6 PubChem CID: 53364540 Formula: C27H26N4O Molecular Weight: 422.52
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: K1498757
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for DAGL?
Compounds associated with DAGL are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does DAGL sit within Metabolic Enzyme/Protease?
DAGL is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from DAGL?
For compounds listed under DAGL, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for DAGL?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring DAGL, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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