EBI2/GPR183

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  1. NIBR 189
    CAS: 1599432-08-2 EC Number: 853-277-2 Formula: C21H21BrN2O3 Molecular Weight: 429.31
    ● In Stock — US warehouse, ships to EU* Item #: N287719
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    Technical Identifiers
    IUPAC Name
    (E)-3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)piperazin-1-yl]prop-2-en-1-one
    SMILES
    COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)C=CC3=CC=C(C=C3)Br
    InChIKey
    OFHXXBRBGWUOHR-NYYWCZLTSA-N
    InChI
    1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+
    Synonyms
    EX-A1054 | SCHEMBL16598583 | (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one | BDBM50011...
  2. 7α,25-dihydroxycholesterol, Agonist of GPR183
    CAS: 64907-22-8 Formula: C27H46O3 Molecular Weight: 418.652
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: D130221
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    Technical Identifiers
    IUPAC Name
    (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenantshow more
    SMILES
    CC(CCCC(C)(C)O)C1CCC2C1(CCC3C2C(C=C4C3(CCC(C4)O)C)O)C
    InChIKey
    BQMSKLCEWBSPPY-IKVTXIKFSA-N
    InChI
    1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20show more
    Synonyms
    9beta,14beta,17alpha-cholest-5-ene-3beta,7alpha,25-triol | 3beta,7alpha,25-Trihydroxycholest-5-ene | cholest-5-en-3be...
  3. NIBR 189
    CAS: 1599432-08-2 EC Number: 853-277-2 Formula: C21H21BrN2O3 Molecular Weight: 429.31
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N421918
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (E)-3-(4-bromophenyl)-1-[4-(4-methoxybenzoyl)piperazin-1-yl]prop-2-en-1-one
    SMILES
    COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C(=O)C=CC3=CC=C(C=C3)Br
    InChIKey
    OFHXXBRBGWUOHR-NYYWCZLTSA-N
    InChI
    1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+
    Synonyms
    EX-A1054 | SCHEMBL16598583 | (2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one | BDBM50011...
  4. ML401
    CAS: 1597489-14-9 PubChem CID: 73169083 Formula: C20H20BrClN2O Molecular Weight: 419.7
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: M648811
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    Technical Identifiers
    IUPAC Name
    (E)-3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one
    SMILES
    C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C=CC3=CC=C(C=C3)Br
    InChIKey
    NXTNVQJKGHAGAX-BJMVGYQFSA-N
    InChI
    1S/C20H20BrClN2O/c21-18-6-1-16(2-7-18)5-10-20(25)24-13-11-23(12-14-24)15-17-3-8-19(22)9-4-17/h1-10H,11-15H2/b10-5+
    Synonyms
    GPR183 | (E)-3-(4-Bromophenyl)-1-(4-(4-Chlorobenzyl)Piperazin-1-Yl)Prop-2-En-1-One
  5. GSK682753A
    CAS: 1334294-76-6 PubChem CID: 126843232 Formula: C23H21Cl3N2O3 Molecular Weight: 479.78
    ◐ .Made to order · 8–12 wks Item #: G647476
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    Technical Identifiers
    IUPAC Name
    8-[(E)-3-(4-chlorophenyl)prop-2-enoyl]-3-[(3,4-dichlorophenyl)methyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one
    SMILES
    C1CN(CCC12CN(C(=O)O2)CC3=CC(=C(C=C3)Cl)Cl)C(=O)C=CC4=CC=C(C=C4)Cl
    InChIKey
    RDDLWMWIRXGSJM-XBXARRHUSA-N
    InChI
    1S/C23H21Cl3N2O3/c24-18-5-1-16(2-6-18)4-8-21(29)27-11-9-23(10-12-27)15-28(22(30)31-23)14-17-3-7-19(25)20(26)13-17/h1-8,13H,9-12,14-15H2/b8-4+
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under EBI2/GPR183?
This listing collects compounds associated with EBI2/GPR183 within our GPCR/G Protein area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for EBI2/GPR183?
Consider the reported potency of each EBI2/GPR183 compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for EBI2/GPR183 compounds?
Each EBI2/GPR183 product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search EBI2/GPR183 compounds by activity or structure?
Yes. Filter the EBI2/GPR183 listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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